Results 231 to 240 of about 194,742 (384)

The helicase domain of Polθ counteracts RPA to promote alt-NHEJ

Nature Structural & Molecular Biology, 2017
Pedro A. Mateos-Gómez, T. Kent, Sarah K. Deng, Shane McDevitt, E. Kashkina, Trung M. Hoang, R. Pomerantz, Agnel Sfeir   +7 more
semanticscholar   +1 more source

Ras pathways help buffer biological timekeeping against metabolic perturbations

The FEBS Journal, EarlyView.
Circadian clocks must be buffered (compensated) against conditions that could affect their rate (period). This figure shows rhythmic peaks of spore formation driven by the clock of the fungus Neurospora: The period is the same under different nutritional conditions in the wild‐type but not in a RasGEF mutant that disrupts an intracellular signaling ...
Patricia Lakin‐Thomas
wiley   +1 more source

Bidirectional eukaryotic DNA replication is established by quasi-symmetrical helicase loading

Science, 2017
Gideon Coster, J. Diffley
semanticscholar   +1 more source

Extension of Autographa californica nuclear polyhedrosis virus host range by interspecific replacement of a short DNA sequence in the p143 helicase gene.

, 1994
G. Croizier, L. Croizier, Olivier Argaud, Didier Poudevigne   +3 more
openalex   +2 more sources

TSC22D1 is a newly identified inhibitor of insulin secretion in pancreatic beta cells

The FEBS Journal, EarlyView.
TSC22D1 acts downstream of glucose signaling and negatively regulates insulin secretion in pancreatic beta cells. Mechanistically, TSC22D1 interacts with FoxO1. Elevated glucose levels enhance the TSC22D1–FoxO1 interaction indirectly by increasing the protein abundance of TSC22D1. Importantly, TSC22D1 and FoxO1 not only physically associate but also co‐
Sümbül Yıldırım, Amit Mhamane, Svenja Lösch, Annika Wieder, Ezgi Ermis, Ann‐Christine König, Sevgican Yilmaz, Stefanie M. Hauck, Fatih Kocabas, Julia Szendroedi, Stephan Herzig, Bilgen Ekim   +11 more
wiley   +1 more source

Identifying new targets for improving terpenoid biosynthesis in Yarrowia lipolytica through random genomic cytosine base editing. [PDF]

Microb Cell Fact
Li Z, Liu B, Lv R, Sun Z, Li Q, Zhang X.
europepmc   +1 more source

Encephalomyocarditis virus RNA polymerase preparations, with and without RNA helicase activity [PDF]

, 1991
T. M. Dmitrieva, K B Norkina, Vadim I. Agol   +2 more
openalex   +1 more source

Posttranslational modifications of phosphodiesterase type 4 enzymes represent novel points for therapeutic targeting

The FEBS Journal, EarlyView.
Enzymes from the phosphodiesterase type 4 family (PDE4) coordinate physiological events driven by the cyclic AMP s(cAMP) signaling pathway by tightly controlling cAMP dynamics in many cell types. Key to this strict regulation is the myriad of posttranslational modifications that alter PDE4 activity, cellular location, and binding partner selection ...
Madihah Hussain, Gonzalo S. Tejeda, George S. Baillie   +2 more
wiley   +1 more source

An overview of RecQ helicases and related diseases. [PDF]

Aging (Albany NY)
Yiu TC, Tu J, Cheung HH.
europepmc   +1 more source

Escherichia coli Rep protein and helicase IV [PDF]

, 1992
Janet E. Yancey-Wrona, Edger R. WOOD, James W. George, Karen Smith, Steven W. Matson   +4 more
openalex   +1 more source