Advances in exosome biomarkers for cervical cancer
Cancer Medicine, Volume 11, Issue 24, Page 4966-4978, December 2022., 2022 Cancer‐derived exosomes may promote CC metastasis by boosting cellular epithelial‐mesenchymal transformation (EMT), controlling the proliferation, invasion, or migration of cancer cells, as well as influencing immune escape and aiding angiogenesis.
Zihan Ran +5 more
wiley +1 more source
Network Pharmacology, Molecular Docking, and MR Analysis: Targets and Mechanisms of Gegen Qinlian Decoction for Helicobacter pylori [PDF]
arXiv, 2023 Objective: The study explored therapeutic targets and mechanisms of Gegen Qinlian Decoction for Helicobacter pylori infection and related gastric cancer using network pharmacology, molecular docking, and Mendelian randomization. Methods: Medicinal components of Gegen Qinlian Decoction were extracted from TCMSP and HERB databases.
arxiv
Diagnosis of Helicobacter pylori using AutoEncoders for the Detection of Anomalous Staining Patterns in Immunohistochemistry Images [PDF]
arXiv, 2023 This work addresses the detection of Helicobacter pylori a bacterium classified since 1994 as class 1 carcinogen to humans. By its highest specificity and sensitivity, the preferred diagnosis technique is the analysis of histological images with immunohistochemical staining, a process in which certain stained antibodies bind to antigens of the ...
arxiv
Improving efficiency of inference in clinical trials with external control data [PDF]
, 2020 Suppose we are interested in the effect of a treatment in a clinical trial. The efficiency of inference may be limited due to small sample size. However, external control data are often available from historical studies. Motivated by an application to Helicobacter pylori infection, we show how to borrow strength from such data to improve efficiency of ...
arxiv +1 more source
Friend and foe: factors influencing the movement of the bacterium Helicobacter pylori along the parasitism-mutualism continuum. [PDF]
, 2014 Understanding the transition of bacterial species from commensal to pathogen, or vice versa, is a key application of evolutionary theory to preventative medicine.
Koskella, Britt, Lin, Derek
core +1 more source
Handling Noisy Labels via One-Step Abductive Multi-Target Learning and Its Application to Helicobacter Pylori Segmentation [PDF]
, 2020 Learning from noisy labels is an important concern in plenty of real-world scenarios. Various approaches for this concern first make corrections corresponding to potentially noisy-labeled instances, and then update predictive model with information of the made corrections.
arxiv +1 more source
Oxidative Stress Resulting From Helicobacter pylori Infection Contributes to Gastric Carcinogenesis. [PDF]
, 2017 Helicobacter pylori is a gram-negative, microaerophilic bacterium that infects the stomach and can lead to, among other disorders, the development of gastric cancer. The inability of the host to clear the infection results in a chronic inflammatory state
Butcher, Lindsay D +3 more
core +2 more sources
Clinical Pharmacology &Therapeutics, Volume 113, Issue 2, Page 423-434, February 2023., 2023 This study evaluated drug–drug interactions (DDIs) between antibiotic and nonantibiotic drugs listed with warnings of severe outcomes in the British National Formulary based on adverse drug reaction (ADR) detectable with routine International Classification of Diseases, Tenth Revision coding.
Tjeerd Pieter van Staa +4 more
wiley +1 more source
Offdiagonal Complexity: A computationally quick complexity measure for graphs and networks [PDF]
Physica A 375, 365 (2007), 2004 A vast variety of biological, social, and economical networks shows topologies drastically differing from random graphs; yet the quantitative characterization remains unsatisfactory from a conceptual point of view. Motivated from the discussion of small scale-free networks, a biased link distribution entropy is defined, which takes an extremum for a ...
arxiv +1 more source
Infectious aetiology of marginal zone lymphoma and role of anti-infective therapy [PDF]
, 2016 Marginal zone lymphomas have been associated with several infectious agents covering both viral and bacterial pathogens and in some cases a clear aetiological role has been established.
Annechini, Giorgia +3 more
core +1 more source