Results 71 to 80 of about 105,962 (297)
This observational study assessed the association between anti‐type 2 biologic agents and the occurrence of autoimmune diseases using a large real‐world claims database. Anti‐IL‐5 and anti‐IgE therapies were associated with an increased occurrence of autoimmune diseases, including rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE ...
Shoichiro Inokuchi
wiley +1 more source
Many roads to reservoirs? How susceptibility and shedding shape host competence in amphibians
Read the free Plain Language Summary for this article on the Journal blog. Abstract Host competence—the ability to acquire, harbour and transmit infections—drives pathogen spread and persistence in multi‐host communities. Evaluating species‐specific competence is critical for predicting transmission, particularly for generalist fungal pathogens like ...
Joseph A. DeMarchi +7 more
wiley +1 more source
Gastrointestinal parasites of a population of emus (Dromaius novaehollandiae) in Brazil
Emus are large flightless birds in the ratite group and are native to Australia. Since the mid-1980s, there has been increased interest in the captive breeding of emus for the production of leather, meat and oil.
S. S. M. Gallo +3 more
doaj +1 more source
A mucin-like peptide from Fasciola hepatica instructs dendritic cells with parasite specific Th1-polarizing activity [PDF]
Fasciolosis is a trematode zoonosis of interest in public health and cattle production. We report here the immunostimulatory effect of a 66 mer mucin-like peptide from Fasciola hepatica (Fhmuc), which synergizes with lipopolysaccharide (LPS) to promote ...
Brossard, Natalie +6 more
core +1 more source
Helminths and Immunological Tolerance [PDF]
Current immunosuppression regimens for solid-organ transplantation have shown disappointing efficacy in the prevention of chronic allograft rejection and carry unacceptable risks including toxicity, neoplasia, and life-threatening infection. Achievement of immunological tolerance (long-term antigen unresponsiveness in an immunocompetent host) presents ...
Johnston, Chris J.C. +4 more
openaire +5 more sources
Background Fasciola hepatica is the most common etiologic agent of fasciolosis, a parasitic disease that affects millions of ruminants worldwide and a zoonotic human infection of public health concern.
Judit Serrat +6 more
doaj +1 more source
Temporal Changes in Total Serum Immunoglobulin E Levels in East German Children and the Effect of Potential Predictors [PDF]
Background: Elevated total serum immunoglobulin E (IgE) levels are a prominent feature of allergic and parasitic diseases. An epidemiologic study was conducted in East German children to describe trends in the development of total serum IgE levels and ...
Brüske, Irene +5 more
core +1 more source
Homo sapiens, industrialisation and the environmental mismatch hypothesis
ABSTRACT For the vast majority of the evolutionary history of Homo sapiens, a range of natural environments defined the parameters within which selection shaped human biology. Although human‐induced alterations to the terrestrial biosphere have been evident for over 10,000 years, the pace and scale of change has accelerated dramatically since the onset
Daniel P. Longman, Colin N. Shaw
wiley +1 more source
SummaryIt has been estimated that chronic infections with viruses, bacteria and parasites contribute to 17·8% of the global burden of cancer, although only a relatively small proportion of the infection‐related cancers can be attributed to helminth infections.
Vennervald, B. J., Polman, K.
openaire +4 more sources
A cosmopolitan parasite of Rattus in the Galápagos rodents raises conservation concerns
We draw attention to a recent study that identified the invasive nematode Mastophorus muris, typically associated with Rattus, infecting two endemic Galápagos rats on islands where no invasive rodents have been previously recorded. This unexpected finding raises concerns about undetected rodent introductions and highlights the urgent need for ...
Jadyn Hartwig, C. Miguel Pinto
wiley +1 more source

