Results 111 to 120 of about 147,872 (284)
Human Vaccines & Immunotherapeutics, 2020 Conserved Moraxella catarrhalis (Mcat) proteins, oligopeptide permease (Opp)A, hemagglutinin (Hag), outer membrane protein (OMP) CD, Pilin A clade 2 (PilA2), and Moraxella surface protein (Msp) 22 have been studied as vaccine candidates.
Dabin Ren +4 more
doaj +1 more source
Lung organoids as a human system for Mycobacteria infection modeling and drug testing
The FEBS Journal, EarlyView.Mycobacterial infections, including tuberculosis (TB) and infections by nontuberculous mycobacteria (NTM), are still public health issues. In 2023, TB caused 1.25 million deaths, while NTM remain a clinical challenge for patients with cystic fibrosis (CF).
Stephen Adonai Leon‐Icaza +4 more
wiley +1 more source
Autocatalytic Activation of Influenza Hemagglutinin
Journal of Molecular Biology, 2006 Enveloped viruses contain surface proteins that mediate fusion between the viral and target cell membranes following an activating stimulus. Acidic pH induces the influenza virus fusion protein hemagglutinin (HA) via irreversible refolding of a trimeric conformational state leading to exposure of hydrophobic fusion peptides on each trimer subunit ...
Lee, Jeong H +2 more
openaire +4 more sources
Structural basis for a human broadly neutralizing influenza A hemagglutinin stem-specific antibody including H17/18 subtypes [PDF]
, 2022 Yulu Chen +12 more
openalex +1 more source
The FEBS Journal, EarlyView.Current methods to control porcine reproductive and respiratory syndrome, a disease affecting pigs, are insufficient and a safer, more effective vaccine is needed. This study describes the design and plant production of a self‐assembling protein nanoparticle vaccine candidate against this disease.
Jordan T. VanderBurgt +5 more
wiley +1 more source
Vaccines, 2018 The first exposure to influenza is thought to impact subsequent immune responses later in life. The consequences of this can be seen during influenza epidemics and pandemics with differences in morbidity and mortality for different birth cohorts.
Ewan P. Plant +5 more
doaj +1 more source
The FEBS Journal, EarlyView.This study investigates the potential of encapsulin as an antigen display platform for the development of a candidate Salmonella vaccine for poultry. Encapsulin constructs were transiently expressed in Nicotiana benthamiana where they accumulated to high levels.
Carly A. Charron +6 more
wiley +1 more source
Influenza A Hemagglutinin Passage Bias Sites and Host Specificity Mutations
Cells, 2019 Animal studies aimed at understanding influenza virus mutations that change host specificity to adapt to replication in mammalian hosts are necessarily limited in sample numbers due to high cost and safety requirements.
Raphael T. C. Lee +4 more
doaj +1 more source
Genome Sequence of an H9N2 Avian Influenza Virus Strain with Hemagglutinin-Neuraminidase Combination, Isolated from a Quail in Guangxi, Southern China [PDF]
, 2017 Liji Xie +10 more
openalex +1 more source