Results 31 to 40 of about 147,872 (284)
Mitogenicity of influenza hemagglutinin glycoproteins and influenza viruses bearing H2-hemagglutinin [PDF]
Infection and Immunity, 1981 The hemagglutinin glycoprotein is responsible for the mitogenic effect of influenza A viruses of the H2N2 subtype. This was indicated by the ability of viruses bearing the H2-hemagglutinin glycoprotein, regardless of its associated neuraminidase, to induce lymphocyte proliferation in normal spleen cell suspensions and by the ability of antisera with ...
R B, Armstrong +4 more
openaire +2 more sources
γδ T Cells Provide Protective Function in Highly Pathogenic Avian H5N1 Influenza A Virus Infection
Frontiers in Immunology, 2018 Given the high mortality rate (>50%) and potential danger of intrapersonal transmission, highly pathogenic avian influenza (HPAI) H5N1 epidemics still pose a significant threat to humans.
Peng Dong +11 more
doaj +1 more source
Pharmaceutics, 2021 Sialic acid that presents on the surface of lung epithelial cells is considered as one of the main binding targets for many respiratory viruses, including influenza and the current coronavirus (SARS-CoV-2) through the viral surface protein hemagglutinin.
Haya A. Alfassam +13 more
doaj +1 more source
Heterologous prime-boost vaccination with H3N2 influenza viruses of swine favors cross-clade antibody responses and protection [PDF]
, 2017 The emergence of multiple novel lineages of H1 and H3 influenza A viruses in swine has confounded control by inactivated vaccines. Because of substantial genetic and geographic heterogeneity among circulating swine influenza viruses, one vaccine strain ...
Claes, Gerwin +8 more
core +2 more sources
Prediction of Antigenic Distance in Influenza A Using Attribute Network Embedding
Viruses, 2023 Owing to the rapid changes in the antigenicity of influenza viruses, it is difficult for humans to obtain lasting immunity through antiviral therapy. Hence, tracking the dynamic changes in the antigenicity of influenza viruses can provide a basis for ...
Fujun Peng, Yuanling Xia, Weihua Li
doaj +1 more source
Sequence variation in the haemagglutinin-neuraminidase gene of human parainfluenza virus type 3 isolates in the UK [PDF]
, 1995 The sequence variation in a 934 base-pair region of the gene encoding the haemagglutinin-neuraminidase of five human parainfluenza virus type 3 (HPIV3) isolates was determined together with that of a prototype UK strain. All of the clinical isolates were
A. J. Easton +6 more
core +2 more sources
eLife, 2019 A longstanding question is how influenza virus evolves to escape human immunity, which is polyclonal and can target many distinct epitopes. Here, we map how all amino-acid mutations to influenza’s major surface protein affect viral neutralization by ...
Juhye M Lee +11 more
doaj +1 more source
Tropical Animal Science Journal, 2022 Virus H9N2 has become the most common subtype of low pathogenic avian influenza (LPAI) in poultry and shows the ability to infect humans. One of the important factors triggering the virus pandemic is the live bird market (LBM).
N. R. Maharani, H. Susetya, M. H. Wibowo
doaj +1 more source
An Open Receptor-Binding Cavity of Hemagglutinin-Esterase-Fusion Glycoprotein from Newly-Identified Influenza D Virus: Basis for Its Broad Cell Tropism. [PDF]
, 2016 Influenza viruses cause seasonal flu each year and pandemics or epidemic sporadically, posing a major threat to public health. Recently, a new influenza D virus (IDV) was isolated from pigs and cattle. Here, we reveal that the IDV utilizes 9-O-acetylated
Chen, Xi +8 more
core +3 more sources
Protein Palmitoylation and Its Role in Bacterial and Viral Infections
Frontiers in Immunology, 2018 S-palmitoylation is a reversible, enzymatic posttranslational modification of proteins in which palmitoyl chain is attached to a cysteine residue via a thioester linkage.
Justyna Sobocińska +3 more
doaj +1 more source