Results 11 to 20 of about 17,475 (217)
On the origin of influenza A hemagglutinin [PDF]
Indian Journal of Microbiology, 2009 Recent advances in phylogenetic methods have produced some reassessments of the ages of the most recent common ancestor of hemagglutinin proteins in known strains of influenza A. This paper applies Bayesian phylogenetic analysis implemented in BEAST to date the nodes on the influenza A hemagglutinin tree.
Gatherer, Derek
core +7 more sources
Journal of Biomedical Science, 2012 Background Avian influenza H5N1 virus is highly pathogenic partially because its H5 hemagglutinin contains a polybasic cleavage site that can be processed by proteases in multiple organs.
Tsai Henry J, Chi Li-Ann, Yu Alice L
doaj +2 more sources
Characterization of Hemagglutinin Negative Botulinum Progenitor Toxins
Toxins, 2017 Botulism is a disease involving intoxication with botulinum neurotoxins (BoNTs), toxic proteins produced by Clostridium botulinum and other clostridia. The 150 kDa neurotoxin is produced in conjunction with other proteins to form the botulinum progenitor
Suzanne R. Kalb +4 more
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Pseudotype-based neutralization assays for influenza: a systematic analysis [PDF]
Frontiers in Immunology, 2015 The use of vaccination against the influenza virus remains the most effective method of mitigating the significant morbidity and mortality caused by this virus.
George William Carnell +6 more
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Influenza hemagglutinin membrane anchor [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2018 Viruses with membranes fuse them with cellular membranes, to transfer their genomes into cells at the beginning of infection. For Influenza virus, the membrane glycoprotein involved in fusion is the hemagglutinin (HA), the 3D structure of which is known from X-ray crystallographic studies.
Steve Gamblin +2 more
exaly +5 more sources
Hemagglutinin-mediated Influenza Viral Entry: Identification of Molecular Determinants on Host Tropism [PDF]
, 2012 Influenza A virus causes seasonal flu in humans and occasionally pandemics in humans and poultry, resulting in high mortality diseases and huge economic loss.
Minxiu Wang (151839)
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Hemagglutinin Structure and Activities [PDF]
Cold Spring Harbor Perspectives in Medicine, 2020 Hemagglutinins (HAs) are the receptor-binding and membrane fusion glycoproteins of influenza viruses. They recognize sialic acid-containing, cell-surface glycoconjugates as receptors but have limited affinity for them, and, as a consequence, virus attachment to cells requires their interaction with several virus HAs. Receptor-bound virus is transferred
Steven J, Gamblin +5 more
openaire +2 more sources
Next-Generation Influenza HA Immunogens and Adjuvants in Pursuit of a Broadly Protective Vaccine
Viruses, 2021 Influenza virus, a highly mutable respiratory pathogen, causes significant disease nearly every year. Current vaccines are designed to protect against circulating influenza strains of a given season.
Kaito A. Nagashima, Jarrod J. Mousa
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Viruses, 2020 Despite the possible relationships between tracheal infection and concomitant infection of the terminal part of the lower respiratory tract (bronchioles/alveoli), the behavior of avian influenza viruses (AIVs), such as H5N1, in the conducting airways is ...
Tomo Daidoji +5 more
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Repositioning Drugs on Human Influenza A Viruses Based on a Novel Nuclear Norm Minimization Method
Frontiers in Physiology, 2021 Influenza A viruses, especially H3N2 and H1N1 subtypes, are viruses that often spread among humans and cause influenza pandemic. There have been several big influenza pandemics that have caused millions of human deaths in history, and the threat of ...
Hang Liang +8 more
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