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Mitogenicity of influenza hemagglutinin glycoproteins and influenza viruses bearing H2-hemagglutinin [PDF]
The hemagglutinin glycoprotein is responsible for the mitogenic effect of influenza A viruses of the H2N2 subtype. This was indicated by the ability of viruses bearing the H2-hemagglutinin glycoprotein, regardless of its associated neuraminidase, to induce lymphocyte proliferation in normal spleen cell suspensions and by the ability of antisera with ...
R B, Armstrong +4 more
openaire +2 more sources
Canine distemper is a highly contagious viral disease in carnivores and represents a serious threat for both wild and domestic animals. The aim of our study was to monitor the occurrence of the canine distemper virus in wildlife from the Czech Republic ...
Eliška Kličková +5 more
doaj +1 more source
Influenza C virus hemagglutinin: comparison with influenza A and B virus hemagglutinins [PDF]
The complete nucleotide sequence of the influenza C/California/78 virus RNA 4 was obtained by using cloned cDNA derived from the RNA segment. This gene is 2,071 nucleotides long and can code for a polypeptide of 654 amino acids. Although there are no convincing sequence homologies between RNA 4 and the hemagglutinin genes of influenza A and B viruses ...
S, Nakada +4 more
openaire +2 more sources
Novel phylogenetic algorithm to monitor human tropism in Egyptian H5N1-HPAIV reveals evolution toward efficient human-to-human transmission [PDF]
Years of endemic infections with highly pathogenic avian influenza (HPAI) A subtype H5N1 virus in poultry and high numbers of infections in humans provide ample opportunity in Egypt for H5N1-HPAIV to develop pandemic potential.
Ursula Dietrich (351656) +24 more
core +1 more source
Avian influenza (AI) is one of the main threats to the poultry industry worldwide. Vaccination efforts are based on inactivated, live attenuated, and recombinant vaccines, where the virus hemagglutinin (HA) is the main component of any vaccine ...
Inkar Castellanos-Huerta +7 more
doaj +1 more source
Is seasonal vaccination a contributing factor to the selection of influenza epidemic variants?
Influenza A/H3N2 viruses are the most common and virulent subtypes for humans. Antigenic drift, changes in antigenicity through the accumulation of mutations in the hemagglutinin (HA) gene is chiefly responsible for the continuing circulation of A/H3N2 ...
Yong Chong, Hideyuki Ikematsu
doaj +1 more source
Phylogenetic analysis of B/Victoria hemagglutinin sequences. [PDF]
Phylogenetic analysis of B/Victoria hemagglutinin sequences.
Marius Surleac (8378823) +13 more
core +1 more source
The study of influenza virus evolution in humans has revealed a significant role of glycosylation profile alterations in the viral glycoproteins – hemagglutinin (HA) and neuraminidase (NA), in the emergence of both seasonal and pandemic strains.
Esteban Cruz +3 more
doaj +1 more source
N-Linked glycosylation of hemagglutinin (HA) has been demonstrated to regulate the virulence and receptor-binding specificity of avian influenza virus (AIV).
Liu-gang TAN +8 more
doaj +1 more source
Heterosubtypic neutralizing monoclonal antibodies cross-protective against H5N1 and H1N1 recovered from human IgM+ memory B cells [PDF]
Background: The hemagglutinin (HA) glycoprotein is the principal target of protective humoral immune responses to influenza virus infections but such antibody responses only provide efficient protection against a narrow spectrum of HA antigenic variants ...
Poon Leo L. M. +92 more
core +1 more source

