Results 141 to 150 of about 6,574 (157)
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Viral hemagglutinin augments peptide‐specific cytotoxic T cell responses
European Journal of Immunology, 1993AbstractIn attempt to increase the induction of peptide‐specific cytolytic T cells (CTL) we investigated the effect of the Newcastle disease virus (NDV) hemagglutinin‐neuraminidase (HN) gene product on the activation of peptide‐specific CTL. Spleen cells of CH3 mice immunized against the influenza nucleoprotein peptide 50–63 (NP 50–63) were ...
P T Emmerson +4 more
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Immune recognition of influenza hemagglutinin as a viral and a neo-self-antigen
Immunologic Research, 1998To analyze mechanisms governing tolerance and autoimmunity to self-antigens, we have generated lineages of transgenic mice that express the influenza virus PR8 hemagglutinin (HA) as a neo-self-antigen. By comparing the HA-specific T and B cell responses that can be induced in HA Tg mice with those that are induced in non-Tg (BALB/c) mice, the ...
Andrew J. Caton +2 more
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Formation of noninfectious viral hemagglutinins in ascites tumor cells
Virology, 1960Abstract The replication of influenza virus in two strains of ascites tumor cells, Ehrlich's and Krebs 2, in vitro and in the mouse peritoneum was compared with growth of this virus in roller tube suspensions of minced chorioallantoic membrane. Extended incubation of tumor cells with influenza or Newcastle viruses resulted in a progressive cell ...
Eaton, M D, Jewell, M, Scala, A R
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Direct role of viral hemagglutinin in B-cell mitogenesis by influenza viruses
Journal of Virology, 1987The mitogenic activity of influenza virus is a function of the hemagglutinin (HA) molecule. Purified HA is mitogenic for murine B lymphocytes but not T lymphocytes. Furthermore, like the intact virus, HA of the H2 (but not H3) subtype is mitogenic only for B cells expressing the class II major histocompatibility complex glycoprotein I-E.
David C. Jackson +5 more
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Virus Research, 1985
We have analyzed the pronase-derived glycopeptides of the hemagglutinin glycoproteins expressed from SV40 vectors carrying cloned cDNA copies of the HA gene and of HA isolated from influenza virions (A/Jap/305/57). The glycopeptides derived from he HA glycoprotein obtained from cloned genes were heterogeneous, ranging in size from 3800 to 2800 daltons.
Richard W. Compans +2 more
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We have analyzed the pronase-derived glycopeptides of the hemagglutinin glycoproteins expressed from SV40 vectors carrying cloned cDNA copies of the HA gene and of HA isolated from influenza virions (A/Jap/305/57). The glycopeptides derived from he HA glycoprotein obtained from cloned genes were heterogeneous, ranging in size from 3800 to 2800 daltons.
Richard W. Compans +2 more
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Experientia, 1965
Une methode est decrite pour la mesure des hemagglutinines virales et des anticorps inhibiteurs des hemagglutinines au moyen d'un systeme photoelectrique et enregistreur automatique — le fragiligraphe. Une suspension des erythrocytes et du virus est introduite dans la microcuvette du fragiligraphe.
D. Danon, D. Danon, A. Kohn, A. Kohn
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Une methode est decrite pour la mesure des hemagglutinines virales et des anticorps inhibiteurs des hemagglutinines au moyen d'un systeme photoelectrique et enregistreur automatique — le fragiligraphe. Une suspension des erythrocytes et du virus est introduite dans la microcuvette du fragiligraphe.
D. Danon, D. Danon, A. Kohn, A. Kohn
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2014
The correlation between precise interactions of influenza A virus hemagglutinins with host cell surface glycans having terminal sialic acids and host range specificity has provoked the development of a high-throughput viral-receptor specificity assay.
Nongluk Sriwilaijaroen +2 more
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The correlation between precise interactions of influenza A virus hemagglutinins with host cell surface glycans having terminal sialic acids and host range specificity has provoked the development of a high-throughput viral-receptor specificity assay.
Nongluk Sriwilaijaroen +2 more
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Virus Research, 1984
The amino-terminal and the carboxy-terminal amino acids of the hemagglutinin-neuraminidase glycoprotein of the Ulster strain of Newcastle disease virus have been analyzed before and after proteolytic activation of the precursor HNo (Mr approximately 82K).
W. Schuy +3 more
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The amino-terminal and the carboxy-terminal amino acids of the hemagglutinin-neuraminidase glycoprotein of the Ulster strain of Newcastle disease virus have been analyzed before and after proteolytic activation of the precursor HNo (Mr approximately 82K).
W. Schuy +3 more
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Biochimica et Biophysica Acta (BBA) - General Subjects, 1986
The neuraminidase associated with the bifunctional protein, hemagglutinin-neuraminidase, of influenza virus has been characterized. The enzyme has a pH optimum of 4.5, does not require Ca2+ and is inactivated (98%) by incubation at 50 degrees C. The enzyme has a Km of 2.00 X 10(-3) M and 0.06 X 10(-3) M with the substrates 2-(3-methoxyphenyl)-N ...
Laurent F. Gabriel, D.Jit S. Arora
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The neuraminidase associated with the bifunctional protein, hemagglutinin-neuraminidase, of influenza virus has been characterized. The enzyme has a pH optimum of 4.5, does not require Ca2+ and is inactivated (98%) by incubation at 50 degrees C. The enzyme has a Km of 2.00 X 10(-3) M and 0.06 X 10(-3) M with the substrates 2-(3-methoxyphenyl)-N ...
Laurent F. Gabriel, D.Jit S. Arora
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Canadian Journal of Microbiology, 1971
Purified Sindbis virus is split into two components upon treatment with ether. These are (a) a hemagglutinin which sediments at 55 S and is non-infectious. This fraction was shown to be devoid of phospholipid and to contain the envelope structural protein of the virion; (b) a fraction sedimenting at 135 S, which is devoid of RNA, but contains viral ...
P. Faulkner, B. Arif
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Purified Sindbis virus is split into two components upon treatment with ether. These are (a) a hemagglutinin which sediments at 55 S and is non-infectious. This fraction was shown to be devoid of phospholipid and to contain the envelope structural protein of the virion; (b) a fraction sedimenting at 135 S, which is devoid of RNA, but contains viral ...
P. Faulkner, B. Arif
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