Results 31 to 40 of about 39,654 (286)

On the origin of influenza A hemagglutinin [PDF]

Indian Journal of Microbiology, 2009
Recent advances in phylogenetic methods have produced some reassessments of the ages of the most recent common ancestor of hemagglutinin proteins in known strains of influenza A. This paper applies Bayesian phylogenetic analysis implemented in BEAST to date the nodes on the influenza A hemagglutinin tree.
openaire   +2 more sources

Mitogenicity of influenza hemagglutinin glycoproteins and influenza viruses bearing H2-hemagglutinin [PDF]

Infection and Immunity, 1981
The hemagglutinin glycoprotein is responsible for the mitogenic effect of influenza A viruses of the H2N2 subtype. This was indicated by the ability of viruses bearing the H2-hemagglutinin glycoprotein, regardless of its associated neuraminidase, to induce lymphocyte proliferation in normal spleen cell suspensions and by the ability of antisera with ...
R B, Armstrong, G M, Butchko, S C, Kiley, M A, Phelan, F A, Ennis   +4 more
openaire   +2 more sources

Overview of Serological Techniques for Influenza Vaccine Evaluation: Past, Present and Future [PDF]

, 2014
Serological techniques commonly used to quantify influenza-specific antibodies include the Haemagglutination Inhibition (HI), Single Radial Haemolysis (SRH) and Virus Neutralization (VN) assays.
Callow, Calza, Chan, Cosma, De Jong, Farrohi, Ferrara, Fox, Frank, Fulton, Gross, Halloran, Harmon, Hierholzer, Johansson, Johansson, Kendal, Kilbourne, Montomoli, Okuno, O’Neill, Powers, Probert, Rowe, Schild, Schulman, Schulman, Scott, Sylte, Van Assen, Yewdell   +30 more
core   +3 more sources

Influenza C virus hemagglutinin: comparison with influenza A and B virus hemagglutinins [PDF]

Journal of Virology, 1984
The complete nucleotide sequence of the influenza C/California/78 virus RNA 4 was obtained by using cloned cDNA derived from the RNA segment. This gene is 2,071 nucleotides long and can code for a polypeptide of 654 amino acids. Although there are no convincing sequence homologies between RNA 4 and the hemagglutinin genes of influenza A and B viruses ...
S, Nakada, R S, Creager, M, Krystal, R P, Aaronson, P, Palese   +4 more
openaire   +2 more sources

One-way trip: Influenza virus' adaptation to gallinaceous poultry may limit its pandemic potential [PDF]

, 2014
We hypothesise that some influenza virus adaptations to poultry may explain why the barrier for human-to-human transmission is not easily overcome once the virus has crossed from wild birds to chickens.
Alexander, Baigent, Banks, Banks, Belser, Blumenkrantz, Bosch, Brass, Bullough, Butt, Castrucci, Cauldwell, Chan, Chen, Chen, Cheng, Chutinimitkul, Cohen, Connor, Costa, Cotter, Cowling, Cox, De Jong, Dorigatti, DuBois, Elderfield, England, Everitt, Gabbard, Galloway, Gambaryan, Gambaryan, Gao, Garten, Handel, Harvey, Hatta, Hay, Herfst, Hoffmann, Imai, Jia, Karron, Keleta, Killingley, Koerner, Koopmans, Krenn, Kuchipudi, Li, Li, Lin, Lin, Linster, Luke, Maines, Matrosovich, Matrosovich, Matrosovich, Matrosovich, Matsuoka, Munier, Neumann, O'Donnell, Pappas, Peiris, Perdue, Reed, Roberts, Robinson, Roche, Rogers, Rott, Russell, Russell, Schrauwen, Shelton, Shi, Skehel, Smeenk, Sorrell, Sorrell, Steinhauer, Stevens, Suguitan, Sun, Tellier, Tharakaraman, Thoennes, Tumpey, Vines, Wan, Wang, Washington, Webster, Wei, Xiong, Yen, Zhang, Zhou, Zhou   +101 more
core   +2 more sources

Hemagglutination and biofilm formation as virulence markers of uropathogenic Escherichia coli in acute urinary tract infections and urolithiasis

Indian Journal of Urology, 2013
Introduction: Urinary tract infections (UTI) are a major public health concern in developing countries. Most UTIs are caused by E. coli, accounting for up to 90% of community-acquired UTIs (CAUTI).
Uma B Maheswari, Sunitha Palvai, Pattepu Rajalingam Anuradha, Nagamani Kammili   +3 more
doaj   +1 more source

Cryo-electron Microscopy Structures of Chimeric Hemagglutinin Displayed on a Universal Influenza Vaccine Candidate

mBio, 2016
Influenza viruses expressing chimeric hemagglutinins (HAs) are important tools in the quest for a universal vaccine. Using cryo-electron tomography, we have determined the structures of a chimeric HA variant that comprises an H1 stalk and an H5 globular ...
Erin E. H. Tran, Kira A. Podolsky, Alberto Bartesaghi, Oleg Kuybeda, Giovanna Grandinetti, Teddy John Wohlbold, Gene S. Tan, Raffael Nachbagauer, Peter Palese, Florian Krammer, Sriram Subramaniam   +10 more
doaj   +1 more source

The Generation of a H9N2 Avian Influenza Virus with HA and C3d-P29 Protein Fusions and Vaccine Development Applications

Vaccines
Background: Maternal-derived antibody (MDA) interferes with immune responses, leading to the failure of H9N2 avian influenza vaccinations in poultry. So far, none of the commercially available H9N2 avian influenza vaccines used in poultry have been able ...
Xue Pan, Fan Zhou, Xiaona Shi, Qinfang Liu, Dawei Yan, Qiaoyang Teng, Chunxiu Yuan, Bangfeng Xu, Zhifei Zhang, Minghao Yan, Zejun Li   +10 more
doaj   +1 more source

Contemporary Avian Influenza A Virus Subtype H1, H6, H7, H10, and H15 Hemagglutinin Genes Encode a Mammalian Virulence Factor Similar to the 1918 Pandemic Virus H1 Hemagglutinin

mBio, 2014
Zoonotic avian influenza virus infections may lead to epidemics or pandemics. The 1918 pandemic influenza virus has an avian influenza virus-like genome, and its H1 hemagglutinin was identified as a key mammalian virulence factor.
Li Qi, Lindsey M. Pujanauski, A. Sally Davis, Louis M. Schwartzman, Daniel S. Chertow, David Baxter, Kelsey Scherler, Kevan L. Hartshorn, Richard D. Slemons, Kathie-Anne Walters, John C. Kash, Jeffery K. Taubenberger   +11 more
doaj   +1 more source

Glycan receptor specificity as a useful tool for characterization and surveillance of influenza A virus [PDF]

, 2014
Influenza A viruses are rapidly evolving pathogens with the potential for novel strains to emerge and result in pandemic outbreaks in humans. Some avian-adapted subtypes have acquired the ability to bind to human glycan receptors and cause severe ...
Jayaraman, Akila, Raman, Rahul, Sasisekharan, Ram, Sasisekharan, Viswanathan, Shriver, Zachary H., Tharakaraman, Kannan   +5 more
core   +1 more source