Results 11 to 20 of about 604 (128)

Multiparameter flow cytometry to detect hematogones and to assess B-lymphocyte clonality in bone marrow samples from patients with non-Hodgkin lymphomas [PDF]

Hematology Reports, 2014
Hematogones are precursors of B-lymphocytes detected in small numbers in the bone marrow. Flow cytometry is the most useful tool to identify hematogones and, so far, 4-color methods have been published.
Giovanni Carulli, Virginia Ottaviano, Valentina Guerri, Stefano Giuntini, Paola Sammuri, Eugenio M. Ciancia, Antonio Azzarà   +6 more
doaj   +2 more sources

Hematogônias: distinção com blastos da leucemia linfóide aguda de células B por citometria de fluxo Hematogones: differentiation from B-lineage acute lymphoblastic leukemia by flow cytometry

Revista Brasileira de Hematologia e Hemoterapia, 2006
Hematogônias são precursores normais de linhagem B que apresentam características morfológicas e, algumas vezes, imunológicas similares aos linfoblastos das leucemias linfóides agudas (LLA).
Fátima M. G. Jorge, Jesamar C. Matos, Maria Helena Pitombeira, Francisco D. Rocha Filho   +3 more
doaj   +2 more sources

Hematogones in immune thrombocytopenic purpura: diagnostic implication

The Turkish Journal of Pediatrics, 2011
Hematogones (HGs) are benign immature B cells in bone marrow with a variety of benign and malignant conditions, including idiopathic thrombocytopenic purpura, leukemia, lymphoma, red blood cell aplasia, iron deficiency anemia, amegakaryocytosis ...
Arzu Akyay, Mesude Falay, Seda Oztürkmen, Zafer Biçakci, Betül Tavil, Gülsüm Ozet, Lale Olcay   +6 more
doaj   +3 more sources

Persistent <i>BCR::ABL1</i>-positive preleukemic stem cells drive late clonal evolution in Philadelphia chromosome-positive ALL. [PDF]

Hemasphere
HemaSphere, Volume 10, Issue 5, May 2026.
Martin JE, Cliquot J, Kim R, Mathis S, Cayuela JM, Passet M, Gaillard B, Himberlin C, Baruchel A, Itzykson R, Soulier J, Boissel N, Raffoux E, Cornillet-Lefebvre P, Clappier E.   +14 more
europepmc   +2 more sources

Daratumumab and isatuximab differentially affect CD38 detection on plasma cells in myeloma: Anti-CD38 nanobody (clone JK36) and CD319 combination improve flow cytometric identification of plasma cells after targeted therapies. [PDF]

Br J Haematol
Daratumumab and isatuximab differentially affect plasma cell identification by anti‐CD38 detection antibodies. HB‐7 and JK36 bind to CD38 epitopes E1 and E3, respectively, and co‐staining of plasma cells in the absence of CD38‐directed drugs results in a diagonal staining pattern (top left).
Shameli A, Catey T, Woodings V, Koepke O, Fromm JR, Cherian S.   +5 more
europepmc   +2 more sources

Harmonization on defining B-cell recovery post CD19-CAR T-cell therapy in B-cell acute lymphoblastic leukemia: An international consensus statement. [PDF]

Hemasphere
Abstract Relapse following CD19‐targeting chimeric antigen receptor T‐cell therapy (CD19‐CAR) remains a major barrier to long‐term cure in relapsed/refractory B‐cell acute lymphoblastic leukemia, with nearly 50% of patients relapsing within 6 months. Early B‐cell recovery (BCR), as detected by the re‐emergence of CD19‐positive cells, has been strongly ...
Lamble A, Bohling SD, Davis KL, Talleur AC, McNerney KO, Naik S, Kumar P, Thomas R, Wang HW, Yuan CM, Jacoby E, Baruchel A, Ghorashian S, Pulsipher MA, Schultz L, Gardner RA, Shah NN.   +16 more
europepmc   +2 more sources

Transition from Morphocytochemical Diagnosis to Immunophenotypic Diagnosis of Acute Leukemia: A Flow Cytometry Experience from Southern Odisha

Medical Journal of Dr. D.Y. Patil Vidyapeeth, 2023
Background: In today’s generation of targeted therapy, traditional reporting of acute leukemia by morphology using the FAB system of classification has limited uses due to a lack of standardization and use in risk stratification.
Chaitali Patnaik, Prasanta Purohit, Samira K. Behera, Swayamprabha Pradhan   +3 more
doaj   +1 more source

CpG-Activated Regulatory B-Cell Progenitors Alleviate Murine Graft-Versus-Host-Disease

Frontiers in Immunology, 2022
Development of Graft Versus Host Disease (GVHD) represents a major impediment in allogeneic hematopoietic stem cell transplantation (HSCT). The observation that the presence of bone marrow and circulating hematogones correlated with reduced GVHD risks ...
Viviane A. Agbogan, Pauline Gastineau, Emmanuel Tejerina, Saoussen Karray, Flora Zavala   +4 more
doaj   +1 more source

A mobile application based on efficient lightweight CNN model for classification of B-ALL cancer from non-cancerous cells: A design and implementation study

Informatics in Medicine Unlocked, 2023
Background: B-cell acute lymphoblastic leukemia (B-ALL) is one of the most widespread cancers, and its definitive diagnosis demands invasive and costly diagnostic tests with side effects for patients.
Azamossadat Hosseini, Mohammad Amir Eshraghi, Tania Taami, Hamidreza Sadeghsalehi, Zahra Hoseinzadeh, Mustafa Ghaderzadeh, Mohammad Rafiee   +6 more
doaj   +1 more source

CD86, the double agent: Significance of CD86 expression in B-cell malignancies. [PDF]

Int J Cancer
Abstract Bypassing the anti‐tumor functions of the immune system is one of the keys to tumor survival. Tumors, especially hematological tumors, produce or express factors that retune T and B cells to inhibit the immune response. Coreceptors CD28 and CTLA‐4, and their ligands, CD80 and CD86, are involved in the immunological synapse and play an ...
Barna G, Szalóki G, Márk Á, Hunyadi A, Kriston C.   +4 more
europepmc   +2 more sources