Results 41 to 50 of about 138,640 (301)

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

XPO1 blockade with KPT-330 promotes apoptosis in cutaneous T-cell lymphoma by activating the p53–p21 and p27 pathways

Scientific Reports
Dysregulated nuclear-cytoplasmic trafficking has been shown to play a role in oncogenesis in several types of solid tumors and hematological malignancies. Exportin 1 (XPO1) is responsible for the nuclear export of several proteins and RNA species, mainly
Nitin Chakravarti, Amy Boles, Rachel Burzinski, Paola Sindaco, Colleen Isabelle, Kathleen McConnell, Anjali Mishra, Pierluigi Porcu   +7 more
doaj   +1 more source

Utility of neurotoxicity investigations in CD19 and BCMA CART recipients with ICANS

Blood Immunology & Cellular Therapy
: Immune effector cell–associated neurotoxicity syndrome (ICANS) is a potentially life-threatening toxicity of chimeric antigen receptor T-cell (CART) therapy, graded according to American Society for Transplantation and Cellular Therapy (ASTCT ...
Lauren N. Scott, Benjamin Hane, William Wesson, Pilar Thangwaritorn, Raeef Rahman, Marc Hoffmann, Forat Lutfi, Zahra Mahmoudjafari, Sunil Abhyankar, Dinesh Pal Mudaranthakam, Muhammad Umair Mushtaq, Joseph McGuirk, Al-Ola Abdallah, Muhammad Mahdi Nashatizadeh, Nausheen Ahmed   +14 more
doaj   +1 more source

Plerixafor (a CXCR4 antagonist) following myeloablative allogeneic hematopoietic stem cell transplantation enhances hematopoietic recovery

Journal of Hematology & Oncology, 2016
Background The binding of CXCR4 with its ligand (stromal-derived factor-1) maintains hematopoietic stem/progenitor cells (HSPCs) in a quiescent state.
Michael M. B. Green, Nelson Chao, Saurabh Chhabra, Kelly Corbet, Cristina Gasparetto, Ari Horwitz, Zhiguo Li, Jagadish Kummetha Venkata, Gwynn Long, Alice Mims, David Rizzieri, Stefanie Sarantopoulos, Robert Stuart, Anthony D. Sung, Keith M. Sullivan, Luciano Costa, Mitchell Horwitz, Yubin Kang   +17 more
doaj   +1 more source

BRAF inhibitor and hairy cell leukemia-related transient acantholytic dermatosis [PDF]

, 2020
Grover disease (GD) is an acquired, nonfamilial, nonimmune mediated, transient or persistent acantholytic dermatosis. Herein, we present a 72-year-old man who had clinical and histopathologic findings of GD following two weeks of treatment with ...
Durkin, John R, Elwood, Hillary, Singh, Amy Garcia, Tchanque-Fossuo, Catherine N   +3 more
core  

Viruses associated with pneumonia in adults. [PDF]

, 2012
Viral pneumonia, which is typically associated with disease in childhood, is increasingly recognized as causing problems in adults. Certain viruses, such as influenza virus, can attack fully immunocompetent adults, but many viruses take advantage of more-
Cesario, Thomas C
core   +1 more source

Real‐World Pediatric Blinatumomab Administration: Access to Outpatient Care Delivery and Impact of a Hospital‐Dispensed Model

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Blinatumomab has been shown to be highly effective for patients with pediatric B‐ALL and has recently become standard of care therapy. Due to its past use in the clinical trial setting, there is limited information available about real‐world administration.
Katelyn Oranges, Kelly A. Duffy, Sara McDonough, Evelyn Kurpiewski, R. Jennifer Randall, Allison Barz Leahy, Haley M. Newman, Joyce P. Lee, Stephen P. Hunger, Anne F. Reilly, David T. Teachey, Susan R. Rheingold, Daniel J. Zheng   +12 more
wiley   +1 more source

Processed human amniotic fluid retains its antibacterial activity

Journal of Translational Medicine, 2019
Background Human amniotic fluid (AF) contains numerous nutrients, trophic factors and defense proteins that provide a nurturing and protective environment for fetal development.
Yong Mao, Jan Pierce, Anya Singh-Varma, Michael Boyer, Joachim Kohn, Jo-Anna Reems   +5 more
doaj   +1 more source

Eosinophilic dermatosis of hematologic malignancy: a case report [PDF]

, 2020
Eosinophilic dermatosis of hematologic malignancy (EDHM) is a dermatosis characterized by tissue eosinophilia that has been previously reported as insect bite-like reaction.
Almeida, FT, Brito, C, Caldas, R, Ferreira, O, Rodrigues, AP   +4 more
core  

Determination of itraconazole and hydroxyitraconazole in plasma by use of liquid chromatography-tandem mass spectrometry with on-line solid-phase extraction [PDF]

, 2003
In this paper a method for the simultaneous quantification of the anti-fungal drug itraconazole and its co-active metabolite hydroxyitraconazole in plasma employing liquid chromatography tandem-mass spectrometry and automated solid-phase extraction is ...
Schiel, Xaver, Spöhrer, Ute, Vogeser, Michael   +2 more
core   +1 more source