Results 31 to 40 of about 267,118 (262)

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

IMPACT OF COVID-19 ON OUTCOMES OF PATIENTS WITH HEMATOLOGIC MALIGNANCIES: A MULTI-CENTER, RETROSPECTIVE STUDY [PDF]

, 2022
Objectives: Patients with hematologic malignancies have a high risk of coronavirus disease 2019 (COVID-19) mortality. This study aimed to investigate the impact of COVID-19 on mortality rates in patients with various hematologic malignancies and to ...
Idris Ince, Erman Ozturk, İbrahim Halil Açar, Emine Gulturk, Nazli Demir, Muzeyyen Aslaner Ak, Sebnem Izmir Güner, Mesut Gocer, Aysun Senturk Yikilmaz, Omer Ekinci, Birol Guvenc, Figen Atalay, Yildiz Ipek, Gulden Sincan, Ali Dogan   +14 more
core   +3 more sources

XPO1 blockade with KPT-330 promotes apoptosis in cutaneous T-cell lymphoma by activating the p53–p21 and p27 pathways

Scientific Reports
Dysregulated nuclear-cytoplasmic trafficking has been shown to play a role in oncogenesis in several types of solid tumors and hematological malignancies. Exportin 1 (XPO1) is responsible for the nuclear export of several proteins and RNA species, mainly
Nitin Chakravarti, Amy Boles, Rachel Burzinski, Paola Sindaco, Colleen Isabelle, Kathleen McConnell, Anjali Mishra, Pierluigi Porcu   +7 more
doaj   +1 more source

Targeting Oncogenic Drivers and Signaling Pathways in Hematologic Malignancies

, 2023
oncogenic drivers; signaling; pathways; hematologic malignancies ...

core  

S100A8 and S100A9 in Hematologic Malignancies: From Development to Therapy [PDF]

, 2023
S100A8 and S100A9 are multifunctional proteins that can initiate various signaling pathways and modulate cell function both inside and outside immune cells, depending on their receptors, mediators, and molecular environment.
Jaebok Choi, Abdul-Jalil Dania, Dania, Abdul-Jalil, Sena Kim, Razmkhah, Farnaz, Kim, Sena, Choi, Jaebok, Farnaz Razmkhah, Lim, Sora, Sora Lim   +9 more
core   +1 more source

Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan, Michael Abele, Calogero Virgone, Michaela Kuhlen, Ricardo Lopez‐Almarez, Tal Ben‐Ami, Ewa Bien, Maja Cesen, Malgorzata A. Krawczyk, Andrea Ferrari, Gianni Bisogno, Yves Reguerre, Dominik T. Schneider, Louise Galmiche, Jorg Fuchs, Sarah Braungart, Bilgehan Yalcin, Ines B. Brecht, Daniel Orbach   +18 more
wiley   +1 more source

Hyperinflammatory differentiation syndrome with hemophagocytic lymphohistiocytosis-like features following menin inhibition in acute myeloid leukemia

Haematologica
Not available.
Kuo-Kai Chin, Ying Liu, Yanming Zhang, William T. Johnson, Yannis K. Valtis, Varun Narendra, Anthony F. Daniyan, Mark B. Geyer, Tamanna Z. Haque, Scott E. Millman, Aaron J. Stonestrom, Sheng F. Cai, Martin S. Tallman, Wenbin Xiao, Eytan M. Stein   +14 more
doaj   +1 more source

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach   +15 more
wiley   +1 more source

Utility of neurotoxicity investigations in CD19 and BCMA CART recipients with ICANS

Blood Immunology & Cellular Therapy
: Immune effector cell–associated neurotoxicity syndrome (ICANS) is a potentially life-threatening toxicity of chimeric antigen receptor T-cell (CART) therapy, graded according to American Society for Transplantation and Cellular Therapy (ASTCT ...
Lauren N. Scott, Benjamin Hane, William Wesson, Pilar Thangwaritorn, Raeef Rahman, Marc Hoffmann, Forat Lutfi, Zahra Mahmoudjafari, Sunil Abhyankar, Dinesh Pal Mudaranthakam, Muhammad Umair Mushtaq, Joseph McGuirk, Al-Ola Abdallah, Muhammad Mahdi Nashatizadeh, Nausheen Ahmed   +14 more
doaj   +1 more source

Plerixafor (a CXCR4 antagonist) following myeloablative allogeneic hematopoietic stem cell transplantation enhances hematopoietic recovery

Journal of Hematology & Oncology, 2016
Background The binding of CXCR4 with its ligand (stromal-derived factor-1) maintains hematopoietic stem/progenitor cells (HSPCs) in a quiescent state.
Michael M. B. Green, Nelson Chao, Saurabh Chhabra, Kelly Corbet, Cristina Gasparetto, Ari Horwitz, Zhiguo Li, Jagadish Kummetha Venkata, Gwynn Long, Alice Mims, David Rizzieri, Stefanie Sarantopoulos, Robert Stuart, Anthony D. Sung, Keith M. Sullivan, Luciano Costa, Mitchell Horwitz, Yubin Kang   +17 more
doaj   +1 more source