Results 11 to 20 of about 99,201 (311)
Immunotherapy in Hematologic Malignancies [PDF]
Current Oncology, 2020 The management of hematologic malignancies has traditionally relied on chemotherapy regimens, many of which are still in use today. However, with advancements in the knowledge of tumour pathophysiology, therapies are continually evolving. Monoclonal antibodies against specific targets on tumour cells are now widely used to treat hematologic ...R R, Kansara, C, Spezialiopenaire +3 more sourcesDevelopment and validation of a novel circular RNA as an independent prognostic factor in acute myeloid leukemia
BMC Medicine, 2021 Background Although there are many clinical and molecular biomarkers in acute myeloid leukemia (AML), the novel and reliable biomarkers are still required to predict the overall survival at the time of disease diagnosis.Jinghan Wang, Jiajia Pan, Shujuan Huang, Fenglin Li, Jiansong Huang, Xia Li, Qing Ling, Wenle Ye, Yungui Wang, Wenjuan Yu, Jie Jin +10 moredoaj +1 more sourceDeubiquitinases in hematological malignancies [PDF]
Biomarker Research, 2021 AbstractDeubiquitinases (DUBs) are enzymes that control the stability, interactions or localization of most cellular proteins by removing their ubiquitin modification. In recent years, some DUBs, such as USP7, USP9X and USP10, have been identified as promising therapeutic targets in hematological malignancies.Hu Lei, Jiaqi Wang, Jiacheng Hu, Qian Zhu, Yingli Wu +4 moreopenaire +3 more sourcesImmunochemotherapy plus lenalidomide for high-risk mantle cell lymphoma with measurable residual disease evaluation
Haematologica, 2023
Chemoimmunotherapy followed by consolidative high-dose therapy with autologous stem cell rescue was a standard upfront treatment for fit patients with mantle cell lymphoma (MCL) in first remission; however, treatment paradigms are evolving in the era of Zachary D. Epstein-Peterson, Esther Drill, Umut Aypar, Connie Lee Batlevi, Philip Caron, Ahmet Dogan, Pamela Drullinsky, John Gerecitano, Paul A. Hamlin, Caleb Ho, Allison Jacob, Ashlee Joseph, Leana Laraque, Matthew J. Matasar, Alison J. Moskowitz, Craig H. Moskowitz, Chelsea Mullins, Colette Owens, Gilles Salles, Heiko Schöder, David J. Straus, Anas Younes, Andrew D. Zelenetz, Anita Kumar +23 moredoaj +1 more sourceHematologic Malignancies
The Oncologist, 2001 Abstract This article reviews highlights in the field of hematologic malignancies presented at the 2001 annual meeting of the American Society of Clinical Oncology. Targeted therapies continue to proceed from the laboratory to the clinic.M, Petryk, M L, Grossbardopenaire +4 more sources“Waitlist mortality” is high for myeloma patients with limited access to BCMA therapy
Frontiers in Oncology, 2023 BackgroundThe first-in-class approved BCMA CAR-T therapy was idecabtagene vicleucel (ide-cel), approved in March 2021, for RRMM patients who progressed after 4 or more lines of therapy.Nausheen Ahmed, William Wesson, Muhammad Umair Mushtaq, Rajat Bansal, Haitham AbdelHakim, Sarah Bromert, Allison Appenfeller, Batool Abu Ghazal, Anurag Singh, Sunil Abhyankar, Siddhartha Ganguly, Siddhartha Ganguly, Joseph McGuirk, Al-Ola Abdallah, Leyla Shune +14 moredoaj +1 more sourceImpact of race and ethnicity on early mortality in multiple myeloma: a SEER analysis
Haematologica, 2023
Over the past two decades, there have been significant advances in the treatment of multiple myeloma which has led to an improvement in overall survival.1,2 However, a notable proportion of patients continue to experience early mortality (EM), defined ...John X. Wei, Aditi Shastri, R. Alejandro Sica, Ioannis Mantzaris, Noah Kornblum, Urvi Shah, Murali Janakiram, Kira Gritsman, Amit Verma, Mendel Goldfinger, Dennis Cooper, Nishi Shah +11 moredoaj +1 more sourceMetabolism in hematologic malignancy [PDF]
Cancer, 1988 The authors used isotopic infusions of 6-3H-glucose, U-14C-glucose, and 14C-urea and calorimetry to investigate energy expenditure and metabolic profiles in 19 patients with hematologic malignancy. The average age of these patients was 62 years. Eleven patients had either leukemia or myeloproliferative disorders (LEMP).D A, Humberstone, J H, Shawopenaire +2 more sourcesCOVID-19 Severity and Survival over Time in Patients with Hematologic Malignancies: A Population-Based Registry Study
, 2023 Mortality rates for COVID-19 have declined over time in the general population, but data in patients with hematologic malignancies are contradictory. We identified independent prognostic factors for COVID-19 severity and survival in unvaccinated patients Martos Martinez, Rafael, Sebrango, Ana, Cristian Escolano Escobar, López-Jiménez, Javier, Javier De la Cruz, José Luis Diez-Martín, Cedillo, Ángel, Miguel Canales, Pedro Sanchez Godoy, Canales, Miguel, Asociación Madrileña de Hematología y Hemoterapia (AMHH), Víctor Jiménez-Yuste, Callejas-Charavia, Marta, Matilla García, Arturo, Isabel González-Gascón, Bastos Oreiro, Mariana Beatriz, Mi Kwon, Estival Monteliu, Pablo, Mariana Bastos, Herráez, Regina, Adrián Alegre, Martínez López, Joaquín, Ángel Cedillo, Yolanda Martínez, Hernández-Rivas, José-Ángel, López Jiménez, Javier, Ruiz, Elena, García-Suárez, Julio, Pérez Oteyza, Jaime, Joaquín Martínez-López, Juan Francisco Del Campo, Elena Ruiz, Diez-Martín, José Luis, Núñez Martín Buitrago, Lucía, Ana Sebrango, Rodrigo Gil-Manso, María Concepción Aláez-Usón, Adolfo de la Fuente, Clara González-Santillana, García Roa, María, Duarte, Rafael, Arroyo Barea, Andrés, Quiroz-Cervantes, Keina, Alonso, Arancha, Martínez-López, Joaquín, Gil Manso, Rodrigo, Matilla, Arturo, Celina Benavente, Jiménez Yuste, Víctor, Belén Rosado Sierra, Herrera Puente, Pilar, de la Fuente, Adolfo, Keina Quiroz-Cervantes, Benavente Cuesta, Celina, Canales Albendea, Miguel Ángel, Pérez-Oteyza, Jaime, Herrera, Pilar, Callejas Charavia, Marta, Fuente, Adolfo de la, Del Campo, Juan Francisco, García Suárez, Julio, Eriel Alexis Marcheco-Pupo, Hernández Rivas, José Ángel, Pablo Estival Monteliu, Cristina Jacome Yerovi, Pascual, Adriana, María García Roa, González Gascón y Marín, Isabel, Martínez-Barranco, Pilar, Marta Callejas-Charavia, Pilar Herrera, Maria Calbacho, Alegre Amor, Adrián, Martínez, Yolanda, Rafael Duarte, Adriana Pascual, Kwon, Mi, Arancha Alonso, Martos-Martinez, Rafael, Pilar Martínez-Barranco, Ortiz, Javier, Rosado Sierra, Belén, Bustelos-Rodriguez, Rosalía, Susana Valenciano, Rafael Martos-Martinez, Quiroz Cervantes, Keina, Pilar Llamas, Carmen Martínez-Chamorro, Ruiz Mediavilla, Elena, Martínez Díez, Yolanda, Javier Ortiz, Llamas, Pilar, González Santillana, Clara, Martínez Barranco, Pilar, Bustelos Rodriguez, Rosalía, Andrés Arroyo Barea, Aláez Usón, María Concepción, Lumbreras Bermejo, Carlos Juan, José Manuel Casas-Rojo, Sánchez Godoy, Pedro, Martínez-Chamorro, Carmen, Lumbreras, Carlos, Jaime Pérez-Oteyza, Casas Rojo, Jose Manuel, Arturo Matilla, Rosalía Bustelos-Rodriguez, Aláez-Usón, María Concepción, José-Ángel Hernández-Rivas, Javier López-Jiménez, Martínez Chamorro, Carmen, González-Santillana, Clara, Julio García-Suárez, Jacome Yerovi, Cristina, Lucía Núñez Martín-Buitrago, Carlos Grande, Díez Martín, José Luis, Regina Herráez, Kwon Kim, Mi, Escolano Escobar, Cristian, Benavente, Celina, Marcheco-Pupo, Eriel Alexis, De La Cruz, Javier, Carlos Lumbreras, Calbacho, Maria, Bastos, Mariana, González-Gascón, Isabel, Casas-Rojo, José Manuel, Grande, Carlos, Gil-Manso, Rodrigo, Alegre, Adrián, Calbacho Robles, Maria, Jiménez-Yuste, Víctor, Núñez Martín-Buitrago, Lucía, Valenciano, Susana +133 morecore +1 more source
