Results 211 to 220 of about 575,997 (353)

Sympathetic Activation Promotes Kidney Fibrosis in Mice via Macrophage‐Derived N2ICD‐Enriched Extracellular Vesicles

open access: yesAdvanced Science, EarlyView.
Norepinephrine/α2B‐adrenoceptor axis promotes the secretion of Notch2 intracellular domain (N2ICD)‐enriched extracellular vesicles (EVs) from macrophages. These EVs deliver N2ICD into fibroblasts, thereby inducing their activation. Deletion of Notch2 or α2B‐AR in macrophages disrupts N2ICD‐enriched EV formation and alleviates kidney fibrosis in mice ...
Huiwen Ren   +14 more
wiley   +1 more source

Reducing emergency department length of stay for hematology patients of tikur anbessa specialized hospital: An improvement initiative. [PDF]

open access: yesPLoS One
Merahi MK   +9 more
europepmc   +1 more source

A Serum‐Stable Antimicrobial Peptide‐Based Delivery Platform for Selective Treatment of Nontargetable and Chemoresistant Tumors

open access: yesAdvanced Science, EarlyView.
A modular antimicrobial‐peptide‐based therapeutic system integrating membrane‐targeted selectivity, a conformation‐driven polyethylene glycolylated blocker, and serum‐stabilizing N‐cap is developed. The optimized conjugate 270 shows potent, rapid killing of the desired tumor cells, high serum stability, low off‐target toxicity, and broad applicability,
Tianxing Liu   +12 more
wiley   +1 more source

Alpha thalassemia and the hematology of homozygous sickle cell disease in childhood [PDF]

open access: bronze, 1986
M.C. Stevens   +9 more
openalex   +1 more source

GSK461364 Inhibits NLRP3 Inflammasome by Targeting NEK7 Phosphorylation

open access: yesAdvanced Science, EarlyView.
Schematic diagram of the mechanism by which GSK461364 inhibits NLRP3 inflammasome activation. GSK461364 inhibits the phosphorylation of NEK7 likely at serine 221 and serine 260 by suppressing the activity of PLK1, thereby restraining the formation of the NLRP3 inflammasome.
Ruiheng Luo   +13 more
wiley   +1 more source

Allogeneic haematopoietic cell transplantation in advanced systemic mastocytosis in new era: A CIBMTR study. [PDF]

open access: yesBr J Haematol
Ustun C   +33 more
europepmc   +1 more source

Hematology for Practitioners. [PDF]

open access: green, 1980
Marshall A. Lichtman
openalex   +1 more source

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