Results 11 to 20 of about 154,498 (360)
Trends in Immunology, 2021 Hematopoiesis is a dynamic process in which stem and progenitor cells give rise to the ~1013 blood and immune cells distributed throughout the human body. We argue that a quantitative description of hematopoiesis can help consolidate existing data, identify knowledge gaps, and generate new hypotheses.
Cosgrove, Jason +3 more
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Cold Spring Harbor Perspectives in Biology, 2012 Enormous numbers of adult blood cells are constantly regenerated throughout life from hematopoietic stem cells through a series of progenitor stages. Accessibility, robust functional assays, well-established prospective isolation, and successful clinical application made hematopoiesis the classical mammalian stem cell system. Most of the basic concepts
Rieger, M., Schroeder, T.
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Development, 2013 Hematopoiesis – the process by which blood cells are formed – has been studied intensely for over a century using a variety of model systems. There is conservation of the overall hematopoietic process between vertebrates, although some differences do exist.
Madhumita, Jagannathan-Bogdan +1 more
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Studies on reticuloendothelial system and hemaotpoiesis. I. Studies of extramedullary hematopoiesis [PDF]
, 1965 The author studied the hematopoietic disturbances of rabbit induced by saponin injection and drew the following conclusions: 1) By saponin injection, the structure of bone marrow is disintegrated and hematopoietic cells are released into the circulating ...
Matsuoka, Kenichi
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MGST1, a GSH transferase/peroxidase essential for development and hematopoietic stem cell differentiation. [PDF]
, 2018 We show for the first time that, in contrast to other glutathione transferases and peroxidases, deletion of microsomal glutathione transferase 1 (MGST1) in mice is embryonic lethal.
Abe, Hiroshi +10 more
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Epigenetics & Chromatin, 2018 Background Enhancers and promoters are cis-acting regulatory elements associated with lineage-specific gene expression. Previous studies showed that different categories of active regulatory elements are in regions of open chromatin, and each category is
Elisabeth F. Heuston +7 more
doaj +1 more source
BMC Biology, 2021 Background Hematopoietic stem cells (HSCs) are the guarantor of the proper functioning of hematopoiesis due to their incredible diversity of potential.
Léonard Hérault +5 more
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BMC Biology, 2021 An amendment to this paper has been published and can be accessed via the original article.
Léonard Hérault +5 more
doaj +1 more source
Fludarabine as a cost-effective adjuvant to enhance engraftment of human normal and malignant hematopoiesis in immunodeficient mice [PDF]
, 2018 There is still an unmet need for xenotransplantation models that efficiently recapitulate normal and malignant human hematopoiesis. Indeed, there are a number of strategies to generate humanized mice and specific protocols, including techniques to ...
A Rambaldi +17 more
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