Results 221 to 230 of about 121,287 (371)

Efficient Generation of Megakaryocyte Progenitors and Platelets From HSPCs via JAK2/STAT3 Signaling

Advanced Science, EarlyView.
This research presents a novel strategy employing the VGM cocktail, which combines HES7 overexpression with HDAC inhibitor and GABA, to enhance platelet production from hematopoietic stem and progenitor cells by promoting megakaryocyte progenitor (MkP) generation.
Huicong Liu, Lingna Wang, Jiaqing Liu, Haitao Yuan, Kaiqing Zhang, Yun Qiu, Fangfang Zhu   +6 more
wiley   +1 more source

The Role of MCPIP1 in Macrophage Polarization and Cardiac Function Post‐Myocardial Infarction

Advanced Science, EarlyView.
Following myocardial infarction, MCPIP1 deficiency in macrophages triggers ferroptosis, driving proinflammatory M1 dominance over reparative M2 phenotypes. This imbalance amplifies splenic monocyte release and sustains cardiac inflammation. Concurrently, excessive inflammatory mediators and insufficient TGF‐β impair fibroblast activation, delaying ...
Xingxu Zhang, Yuan Fang, Xiaoming Qin, Yiwei Zhang, Bo Kang, Li Zhong, Baoxin Liu, Jiachen Luo, Yidong Wei   +8 more
wiley   +1 more source

The Influences of Salivary Gland Hormone on the Hematopoiesis of Bone Marrow

, 1962
Masaaki Ugaki
openalex   +2 more sources

Effect of age on hematopoiesis in man [PDF]

, 1984
DA Lipschitz, KB Udupa, KY Milton, C. Thompson   +3 more
openalex   +1 more source

Optimization of Lipid Nanoparticles with Robust Efficiency for the Delivery of Protein Therapeutics to Augment Cancer Immunotherapy

Advanced Science, EarlyView.
This study develops lipid nanoparticles (LNPs) combining cationic and ionizable lipids for efficient cytosolic protein delivery. Optimized LNPs deliver functional proteins, including antibodies, enzymes, and Cas9, with high serum stability and albumin‐mediated endocytosis.
Lanfang Ren, Zeda Zhao, Yuqing Chao, Panting Yu, Zhoufang Mei, Bing Du, Yiyun Cheng   +6 more
wiley   +1 more source

In vitro restoration of polyclonal hematopoiesis in a chronic myelogenous leukemia after in vitro treatment with 4- hydroperoxycyclophosphamide [PDF]

, 1985
G Degliantoni, L Mangoni, Vittorio Rizzoli   +2 more
openalex   +1 more source

The Dynamic Landscape of 3′‐UTR Alternative Polyadenylation Across Mouse Fetal Development and Anatomy

Advanced Science, EarlyView.
This work maps 3′‐UTR APA across mouse fetal development and tissues, identifying conserved sequence determinants that influence pAS choice. In fetal brain tissues, complex APA dynamics during development are potentially regulated by RBPs like Rbm38, which restrict distal pAS usage.
Qin Wang, Xin Chen, Xiao‐Ou Zhang
wiley   +1 more source

Mutual Regulation of Cardiovascular and Hematopoietic Development. [PDF]

Curr Cardiol Rep
Liu N, Nakano H, Nakano A.
europepmc   +1 more source

RESTORATION OF HEMATOPOIESIS IN DOGS BY INFUSION OF CRYOPRESERVED AUTOLOGOUS PERIPHERAL WHITE CELLS FOLLOWING BUSULFAN-CYCLOPHOSPHAMIDE TREATMENT

, 1975
Kim M. Debelak-Fehir, Robert B. Epstein
openalex   +1 more source

Lithium stimulation of murine hematopoiesis in liquid culture: an effect mediated by marrow stromal cells [PDF]

, 1984
PJ Quesenberry, MA Coppola, RJ Gualtieri, PM Wade, Z Song, MA Doukas, CE Shideler, Baker Dg, EH McGrath   +8 more
openalex   +1 more source