Clinical features and outcomes of myelodysplastic syndrome patients with iron overload: a single-center retrospective study. [PDF]
Huang L+7 more
europepmc +1 more source
Chipping in on clonal hematopoiesis
Eric Padron, Nancy K. Gillis
openaire +3 more sources
Metabolic Programming Drives Protective and Inflammatory Monocyte Fates in Viral Encephalitis
Bone marrow monocytes infiltrate the West Nile virus‐infected brain and differentiate into HIF1‐α⁺ monocyte‐derived cells (MCs) that diverge into protective, antigen‐presenting or inflammatory, iNOS⁺ MCs with distinct metabolic programs and functions.
Claire L. Wishart+4 more
wiley +1 more source
Extramedullary Hematopoiesis Presenting as Pleural Thickening in a Patient With Choroidal Melanoma. [PDF]
Li S, Mubin A, Cantu D.
europepmc +1 more source
Manipulating Unisexual–Sexual Reproduction Transition to Engineer Genome‐Reconstructed Polyploids
This study developed an efficient approach to generate genome‐reconstructed polyploids involving unisexual gynogenetic Carassius gibelio, sexual C. auratus, and sexual C. cuvieri. The selected superior clone inherited gynogenesis ability of C. gibelio and herpesvirus resistance of wild C.
Meng Lu+9 more
wiley +1 more source
A Network‐Driven Framework for Drug Response Precision Prediction of Acute Myeloid Leukemia
A network‐based precision medicine platform, named NetAML is offered for personalized treatment of AML. It combines network analysis and machine learning to develop 87 models predicting drug sensitivity for clinical drugs. NetAML identifies interpretable gene signatures that drive differential drug responses, enabling the prediction of individual ...
Yinyin Wang+7 more
wiley +1 more source
Inferred clonal hematopoiesis from tumor DNA sequencing among men with prostate cancer: correlation with somatic tumor alterations and outcomes. [PDF]
Iranmanesh Y+14 more
europepmc +1 more source
This study identifies the RUNX1/SLAMF3 axis as a key driver of colorectal cancer liver metastasis (CRLM). SLAMF3 suppresses macrophage phagocytosis and depletes C1QC⁺ tumor‐associated macrophages, promoting an immunosuppressive microenvironment. Targeting this axis restores macrophage and CD8⁺ T cell activity and reduces metastasis.
Yinheng Luo+10 more
wiley +1 more source
Extramedullary Hematopoiesis in the Appendix Associated With Myelodysplastic Syndrome: A Case Report. [PDF]
Kinjo N+4 more
europepmc +1 more source