Results 21 to 30 of about 159,775 (264)

Identification of stromal cells in spleen which support myelopoiesis [PDF]

open access: yes, 2019
Stromal cells in spleen organize tissue into red pulp, white pulp and marginal zone, and also interact with hematopoietic cells to regulate immune responses.
Lim, Hong, O'Neill, Helen C
core   +2 more sources

Single-cell RNA-seq reveals a concomitant delay in differentiation and cell cycle of aged hematopoietic stem cells

open access: yesBMC Biology, 2021
Background Hematopoietic stem cells (HSCs) are the guarantor of the proper functioning of hematopoiesis due to their incredible diversity of potential.
Léonard Hérault   +5 more
doaj   +1 more source

Studies on reticuloendothelial system and hemato-poiesis, III. Relationship between differentiation of erythroblast and oxygen tension [PDF]

open access: yes, 1965
For the purpose to clarify the control mechanism of erythroid cell differentiation, the author observed morphologic changes in bone-marrow cells and circulating red cells in phenylhydrazine anemia of rabbits by introducing a mass of red cells into vein ...
Matsuoka, Kenichi
core   +1 more source

CSF1R regulates the dendritic cell pool size in adult mice via embryo-derived tissue-resident macrophages

open access: yesNature Communications, 2018
Dendritic cells (DC) are important regulators of both innate and adaptive immunity, but how the DC pool is homeostatically maintained in vivo is unclear.
Gulce Itir Percin   +6 more
doaj   +1 more source

Comprehensive network modeling from single cell RNA sequencing of human and mouse reveals well conserved transcription regulation of hematopoiesis

open access: yesBMC Genomics, 2020
Background Presently, there is no comprehensive analysis of the transcription regulation network in hematopoiesis. Comparison of networks arising from gene co-expression across species can facilitate an understanding of the conservation of functional ...
Shouguo Gao   +5 more
doaj   +1 more source

The Potential of Tissue-Resident Memory T Cells for Adoptive Immunotherapy against Cancer

open access: yesCells, 2021
Tissue-resident memory T cells (TRM) comprise an important memory T cell subset that mediates local protection upon pathogen re-encounter. TRM populations preferentially localize at entry sites of pathogens, including epithelia of the skin, lungs and ...
Ammarina Beumer-Chuwonpad   +3 more
doaj   +1 more source

Haemogenic endocardium contributes to transient definitive haematopoiesis. [PDF]

open access: yes, 2013
Haematopoietic cells arise from spatiotemporally restricted domains in the developing embryo. Although studies of non-mammalian animal and in vitro embryonic stem cell models suggest a close relationship among cardiac, endocardial and haematopoietic ...
Arshi, Armin   +14 more
core   +1 more source

CD82 expression marks the endothelium to hematopoietic transition at the onset of blood specification in human

open access: yesiScience, 2023
Summary: During embryonic development, all blood progenitors are initially generated from endothelial cells that acquire a hemogenic potential. Blood progenitors emerge through an endothelial-to-hematopoietic transition regulated by the transcription ...
Sara Menegatti   +5 more
doaj   +1 more source

Modelling hematopoiesis mediated by growth factors with applications to periodic hematological diseases [PDF]

open access: yes, 2006
Hematopoiesis is a complex biological process that leads to the production and regulation of blood cells. It is based upon differentiation of stem cells under the action of growth factors.
Adimy, Mostafa   +2 more
core   +5 more sources

Aging and Hematopoiesis

open access: yesClinics in Geriatric Medicine, 2019
In hematopoiesis, mature blood cells, granulocytes, erythrocytes, and megakaryocytes originate from hematopoietic stem cells. With age, changes in hematopoiesis may have clinical consequences: defective immune responses, cytopenias (most commonly anemia and lymphopenia), hematological malignancy, and effects mediated by hematopoietic cells in other ...
Emma M, Groarke, Neal S, Young
openaire   +3 more sources

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