Results 31 to 40 of about 157,726 (359)

Enkephalins in hematopoiesis

Biomedicine & Pharmacotherapy, 1997
Recent data support the view that neuropeptide mediators, in particular opioid peptides, participate in the control of hematopoiesis. The main arguments are: neuropeptides modulate the functions of lymphoid cells, macrophages and mature granulocytes; they control cell proliferation and differentiation in many tissues, particularly during embryogenesis;
Jelka Gabrilovac, L Krizanac-Bengez, M Boranic, Breljak D, T Marotti   +4 more
openaire   +5 more sources

Bone Marrow Harbors a Unique Population of Dendritic Cells with the Potential to Boost Neutrophil Formation upon Exposure to Fungal Antigen

Cells, 2021
Apart from controlling hematopoiesis, the bone marrow (BM) also serves as a secondary lymphoid organ, as it can induce naïve T cell priming by resident dendritic cells (DC).
Marieke Goedhart, Edith Slot, Maria F. Pascutti, Sulima Geerman, Timo Rademakers, Benjamin Nota, Stephan Huveneers, Jaap D. van Buul, Katherine C. MacNamara, Carlijn Voermans, Martijn A. Nolte   +10 more
doaj   +1 more source

Differential Hox expression in murine embryonic stem cell models of normal and malignant hematopoiesis [PDF]

, 2011
The Hox family are master transcriptional regulators of developmental processes, including hematopoiesis. The Hox regulators, caudal homeobox factors (Cdx1-4), and Meis1, along with several individual Hox proteins, are implicated in stem cell expansion ...
Alexander Thompson, Belotti D, Buske C, Deschamps J, Edwina Dobbin, Glenda J. Dickson, Helen Wheadon, Joanne M. Ramsey, Lawrence HJ, Pamela M. Corrigan, Robin W. Freeburn   +10 more
core   +1 more source

Evolution of clonal hematopoiesis

Clinical and Translational Medicine, 2023
Contains fulltext : 300034.pdf (Publisher’s version ) (Open Access)
Isabelle A. van Zeventer, Aniek O. de Graaf, Joop H. Jansen, Gerwin Huls   +3 more
openaire   +5 more sources

In vitro human embryonic stem cell hematopoiesis mimics MYB-independent yolk sac hematopoiesis [PDF]

, 2014
Although hematopoietic precursor activity can be generated in vitro from human embryonic stem cells, there is no solid evidence for the appearance of multipotent, self-renewing and transplantable hematopoietic stem cells.
De Bleser, Dominique, De Mulder, Katrien, Kerre, Tessa, Lambrecht, Bart, Leclercq, Georges, Menten, Björn, Philippé, Jan, Taghon, Tom, Van Caeneghem, Yasmine, Van Roy, Nadine, Vandekerckhove, Bart, Vanhee, Stijn, Velghe, Imke, Verstichel, Greet   +13 more
core   +3 more sources

MEIS1 regulates early erythroid and megakaryocytic cell fate

Haematologica, 2014
MEIS1 is a transcription factor expressed in hematopoietic stem and progenitor cells and in mature megakaryocytes. This biphasic expression of MEIS1 suggests that the function of MEIS1 in stem cells is distinct from its function in lineage committed ...
Sabrina Zeddies, Sjoert B. G. Jansen, Franca di Summa, Dirk Geerts, Jaap J. Zwaginga, C. Ellen van der Schoot, Marieke von Lindern, Daphne C. Thijssen-Timmer   +7 more
doaj   +1 more source

RNA-Binding Protein Expression Alters Upon Differentiation of Human B Cells and T Cells

Frontiers in Immunology, 2021
B cells and T cells are key players in the defence against infections and malignancies. To exert their function, B cells and T cells differentiate into effector and memory cells. Tight regulation of these differentiation processes is key to prevent their
Nordin D. Zandhuis, Nordin D. Zandhuis, Benoit P. Nicolet, Benoit P. Nicolet, Monika C. Wolkers, Monika C. Wolkers   +5 more
doaj   +1 more source

The Shape Shifting Story of Reticulocyte Maturation

Frontiers in Physiology, 2018
The final steps of erythropoiesis involve unique cellular processes including enucleation and reorganization of membrane proteins and the cytoskeleton to produce biconcave erythrocytes. Surprisingly this process is still poorly understood.
Elina Ovchynnikova, Elina Ovchynnikova, Francesca Aglialoro, Francesca Aglialoro, Marieke von Lindern, Marieke von Lindern, Emile van den Akker, Emile van den Akker   +7 more
doaj   +1 more source

CREB is a critical regulator of normal hematopoiesis and leukemogenesis [PDF]

, 2008
The cAMP-responsive element binding protein (CREB) is a 43-kDa nuclear transcription factor that regulates cell growth, memory, and glucose homeostasis. We showed previously that CREB is amplified in myeloid leukemia blasts and expressed at higher levels
Akashi, Akashi, Bai, Bottazzi, Bruserud, Cheng, Christensen, Conkright, Crans-Vargas, Deepa B. Shankar, Dejah R. Judelson, Desdouets, Deshpande, Elliot M. Landaw, Fried, Fu, Hestdal, Impey, Ingrid Schmid, Jamieson, Jenny Chang, Jerry C. Cheng, Kathleen M. Sakamoto, Kentaro Kinjo, Kim, Kinjo, Kohn, Kondo, Koschmieder, Koya, Krishan, Kwon, Lee, Mayr, Mendoza, Miyoshi, Montminy, Ninomiya, Noriyuki Kasahara, Passegué, Ravi Bhatia, Rehemtulla, Renata Stripecke, Scherr, Shah, Shankar, Shankar, Shaywitz, Stripecke, Traver, Tuschl, Van Etten, Ventura, Winston S. Wu, Wong, Yuan   +55 more
core   +3 more sources

Osteoclasts and hematopoiesis [PDF]

BoneKEy Reports, 2012
The skeletal tissue is closely associated with the hematopoietic tissue lodged in its inner cavities. Besides the well-known role of the endosteal osteoblasts in the maintenance of the hematopoietic stem cell (HSC) niche, it is an emerging concept that osteoclasts are involved in the regulation of hematopoiesis as well, although published data are ...
openaire   +4 more sources