Results 71 to 80 of about 102,104 (304)
Extramedullary Hematopoiesis in Cerebellar Hemangioblastoma
, 1991 Extramedullary hematopoiesis and paraneoplastic erythrocytosis are uncommon in cerebellar hemangioblastoma, and their concomitant occurrence has not been reported.
Natasa Zec, Javad Towfighi, Peter Cera
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Antioxidant and Antityrosinase Activity of Extract
Natural Product Communications, 2013 The effects of Cissus quadrangularis Linn. extract on antioxidation and tyrosinase inhibition were investigated. The extract showed anti-oxidative activity with an IC 50 value of 522.0 μg/mL, and inhibitory effects on tyrosinase activity and melanin ...
Ikuko Suzu +6 more
doaj +1 more source
M-Sec facilitates intercellular transmission of HIV-1 through multiple mechanisms
Retrovirology, 2020 Background HIV-1 promotes the formation of tunneling nanotubes (TNTs) that connect distant cells, aiding cell-to-cell viral transmission between macrophages.
Sameh Lotfi +6 more
doaj +1 more source
The RUNX1b Isoform Defines Hemogenic Competency in Developing Human Endothelial Cells
Frontiers in Cell and Developmental Biology, 2021 The transcription factor RUNX1 is a master regulator of blood cell specification. During embryogenesis, hematopoietic progenitors are initially generated from hemogenic endothelium through an endothelium-to-hematopoietic transition controlled by RUNX1 ...
Sara Menegatti +8 more
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Biomedicine & Pharmacotherapy, 1997 Recent data support the view that neuropeptide mediators, in particular opioid peptides, participate in the control of hematopoiesis. The main arguments are: neuropeptides modulate the functions of lymphoid cells, macrophages and mature granulocytes; they control cell proliferation and differentiation in many tissues, particularly during embryogenesis;
Gabrilovac, Jelka +4 more
openaire +4 more sources
, 2023 International audienceThis article highlights the presentations from the 2021 scientific meeting of the Club Hematopoiesis and Oncogenesis. This annual meeting focuses on hematopoiesis and oncogenic mechanisms. Various topics were presented: expansion of
de Sepulveda, Paulo +10 more
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Pediatric Mediastinal Gray Zone Lymphoma With Germline TET2 Heterozygous Variant
Pediatric Blood &Cancer, EarlyView.
Matthew R. Schuelke +9 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source