Results 71 to 80 of about 109,190 (303)
Antioxidant and Antityrosinase Activity of Extract
Natural Product Communications, 2013 The effects of Cissus quadrangularis Linn. extract on antioxidation and tyrosinase inhibition were investigated. The extract showed anti-oxidative activity with an IC 50 value of 522.0 μg/mL, and inhibitory effects on tyrosinase activity and melanin ...
Ikuko Suzu +6 more
doaj +1 more source
Hemoglobin switching in mice carrying the Klf1Nan variant
Haematologica, 2020 Haploinsufficiency for transcription factor KLF1 causes a variety of human erythroid phenotypes, such as the In(Lu) blood type, increased HbA2 levels, and hereditary persistence of fetal hemoglobin. Severe dominant congenital dyserythropoietic anemia IV
Anne Korporaal +7 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Purpose To explore caregivers' experiences and perceptions of the nutritional challenges faced by children and adolescents undergoing cancer treatment, including oral intake and the use of nutritional support. Methods This was a qualitative study based on focus groups with parents and caregivers at a Brazilian pediatric oncology hospital ...
Danyelle Apparecida Balsamão Marques +5 more
wiley +1 more source
M-Sec facilitates intercellular transmission of HIV-1 through multiple mechanisms
Retrovirology, 2020 Background HIV-1 promotes the formation of tunneling nanotubes (TNTs) that connect distant cells, aiding cell-to-cell viral transmission between macrophages.
Sameh Lotfi +6 more
doaj +1 more source
The RUNX1b Isoform Defines Hemogenic Competency in Developing Human Endothelial Cells
Frontiers in Cell and Developmental Biology, 2021 The transcription factor RUNX1 is a master regulator of blood cell specification. During embryogenesis, hematopoietic progenitors are initially generated from hemogenic endothelium through an endothelium-to-hematopoietic transition controlled by RUNX1 ...
Sara Menegatti +8 more
doaj +1 more source
Extramedullary Hematopoiesis Niche in the Spleen [PDF]
, 2017 Hematopoiesis is a process in which the Hematopoietic stem cells (HSC’s) differentiate to give rise to all lineages of blood cells. In normal adults, HSC’s reside in the bone marrow (BM) and their cell niche (microenvironment) in the BM is well-studied ...
Mohamed, Asmaa, +2 more
core +1 more source
Clinical & Translational Immunology, 2022 Objectives High‐magnitude CD8+ T cell responses are associated with mild COVID‐19 disease; however, the underlying characteristics that define CD8+ T cell‐mediated protection are not well understood.
Jet van denDijssel +15 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Central nervous system (CNS) relapse of neuroblastoma carries a poor prognosis, and craniospinal irradiation (CSI) poses substantial long‐term toxicity in young children. We report a toddler with MYCN‐amplified neuroblastoma harboring somatic ALK R1275Q who developed extensive leptomeningeal relapse with paraplegia.
Jinwoo Kim +11 more
wiley +1 more source
The role of survivin2 in primitive hematopoiesis during zebrafish development
, 2009 Survivin is an inhibitor of apoptosis and its role in embryonic development is not completely understood. In zebrafish, survivin undergoes gene duplication. Survivin1 (sur1) has been shown to mediate angiogenesis but not hematopoiesis.
Chung, MIS +3 more
core +1 more source
Hematopoiesis: a Brief Overview [PDF]
, 2022 Hematopoiesis represents the continuous process of formation of all the blood cells, that occurs throughout life, starting from the hematopoietic stem cells (HSCs).
Victoria BUZA +3 more
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