Results 81 to 90 of about 109,190 (303)
Biomedicine & Pharmacotherapy, 1997 Recent data support the view that neuropeptide mediators, in particular opioid peptides, participate in the control of hematopoiesis. The main arguments are: neuropeptides modulate the functions of lymphoid cells, macrophages and mature granulocytes; they control cell proliferation and differentiation in many tissues, particularly during embryogenesis;
Gabrilovac, Jelka +4 more
openaire +4 more sources
Scientific ReportsUnderstanding how mechanical stress affects erythropoiesis is crucial to produce transfusable erythrocytes in fluid-turbulent bioreactors. We investigated the effects of shear-stress on differentiating CD49d+CD235a+ primary human erythroblasts (EBL) at ...
Giulia Iacono +14 more
doaj +1 more source
Stem Cell Research, 2017 Mobilized peripheral blood (MPB) CD34+ cells were differentiated to CD34+/CD41+ megakaryoblasts. Cells were sorted to obtain a pure megakaryoblast population which was reprogrammed with a hOKSM self-silencing polycistronic lentiviral vector.
Marten Hansen +6 more
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola +4 more
wiley +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa +7 more
wiley +1 more source
A novel hairless highly immunodeficient mice model optimized for in vivo imaging
Laboratory Animal ResearchBackground In vivo imaging is one of the analytical technologies that has been rapidly growing in demand in recent years to non-invasively observe the behavior of molecules such as genes and proteins in vivo and perform quantitative and qualitative ...
Kouki Matsuda +4 more
doaj +1 more source
Natural Product Communications, 2014 The purposes of this study were to investigate the inhibitory effects of Salacia reticulata Tul. root extract on cellular oxidants and melanogenesis in B16 melanoma cells. Cells treated with non-toxic doses of S. reticulata root extract were investigated
Prasit Sirwannalert +3 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
A New Transcription Factor in Hematopoiesis [PDF]
, 2020 Background: Hematopoiesis, is all the cells within the blood system being formed in a specific hierarchy from a small community of hematopoietic stem cells.
Kumru, Selahattin +3 more
core
Improved Human Erythropoiesis and Platelet Formation in Humanized NSGW41 Mice
Stem Cell Reports, 2016 Human erythro-megakaryopoiesis does not occur in humanized mouse models, preventing the in vivo analysis of human hematopoietic stem cell (HSC) differentiation into these lineages in a surrogate host.
Susann Rahmig +10 more
doaj +1 more source