Results 131 to 140 of about 416,052 (359)

Hydrogel Confinement Strategies for 3D Cell Culture in Microfluidic Systems

Advanced Materials Technologies, EarlyView.
Hydrogel confinement structures are key to organizing 3D cell cultures in microfluidic devices. This review classifies five structural strategies (micropillar, phaseguide, porous membrane, stepped‐height, and support‐free) and examines their trade‐offs alongside fabrication methods.
Soohyun Kim, Min Seok Lee, Sung Kyun Lee
wiley   +1 more source

Association of dietary patterns with all-cause and cardiovascular disease mortality in cardiovascular-kidney-metabolic syndrome: a cohort study

Nutrition Journal
Background Cardiovascular-kidney-metabolic (CKM) syndrome, defined by the coexistence of cardiovascular disease (CVD), chronic kidney disease, and metabolic disorders, significantly increases mortality risk.
Ya Shao, Yu Wang, Desheng Luo, Xu Zhou, Maoqian Chen, Longti Li, Huiqin Zhong   +6 more
doaj   +1 more source

Engineered Microfluidic Organoid Systems: New Paradigms for Menopause Mechanism Research and Personalized Medicine

Advanced Materials Technologies, EarlyView.
This review explores the integration of microfluidic technology with organoid systems as an innovative platform for studying menopausea complex multi‐organ condition. By enabling precise simulation of inter‐organ communication and hormone responses, microfluidic organoids offer a physiologically relevant model for investigating menopausal syndrome and ...
Qianyi Zhang, He Huang, Hongliang Dong, Qiang Ma, Hongyan Jin   +4 more
wiley   +1 more source

P402: MUTATIONS IN BONA FIDE ONCOGENES KRAS AND DNMT3A ARE NOT RELATED TO DEPENDENCY IN ESTABLISHED TUMORS, IN PDX MODELS OF ACUTE LEUKEMIA IN VIVO

HemaSphere, 2022
Y. Gao, M. Ghalandary, M. Becker, D. Amend, M. Rothenberg-Thurley, K. Metzeler, I. Jeremias   +6 more
doaj   +1 more source

Hematopoietic Stem Cell Gene-Addition/Editing Therapy in Sickle Cell Disease [PDF]

, 2022
Paula Germino-Watnick, Malikiya Hinds, Anh‐Tuan Le, Rebecca Chu, Xiong Liu, Naoya Uchida   +5 more
openalex   +1 more source

Pre‐Administration of Akkermansia Muciniphila Prevents the Development of Severe Acute Graft‐Versus‐Host Disease in Systemic Organs

Advanced Science, EarlyView.
Akkermansia muciniphila, a next‐generation probiotic, alleviates acute graft‐versus‐host disease (aGvHD) following allogeneic hematopoietic stem cell transplantation (HSCT) by providing protective effects across multiple organs. Pre‐colonization with A.
Jeong‐Eun Han, Dae‐Seong Lee, Su‐Won Jeong, Ji‐Hyun Yun, Seomin Kang, Seoyoung Jang, EunAh Lee, Ju Hye Baek, Che Ok Jeon, Jin‐Woo Bae   +9 more
wiley   +1 more source

P1332: PROMISING OUTCOME OF PATIENTS OLDER THAN 70 YEARS WHO UNDERWENT PERIPHERAL BLOOD HAPLOIDENTICAL HEMATOPOIETIC STEM CELL TRANSPLANTATION FOR ACUTE MYELOID LEUKEMIA OR HIGH RISK MYELODYSPLASTIC SYNDROME

, 2022
S. Harbi, Louison Brac de la Perriere, Sylvain Garciaz, T. Pagliardini, B. Calmels, M. Cecile, Y. Hicheri, B. Bouchacourt, A. Calleja, F. Dachy, S. Fürst, C. Lemarie, C. Braticevic, G. Morel, F. Legrand, E. Bekrieva, A. Granata, P. J. Weiller, C. Chabannon, Norbert Vey, Didier Blaise, R. Devillier   +21 more
openalex   +1 more source

Training the Fetal Immune System Through Maternal Inflammation-A Layered Hygiene Hypothesis. [PDF]

, 2020
Over the last century, the alarming surge in allergy and autoimmune disease has led to the hypothesis that decreasing exposure to microbes, which has accompanied industrialization and modern life in the Western world, has fundamentally altered the immune
Apostol, April C, Beaudin, Anna E, Jensen, Kirk DC   +2 more
core  

ROS Activated NETosis of Bone Marrow CD55+ Intermediate Mature Neutrophils Through HIF1α‐PADI4 Pathway to Initiate Bone Aging

Advanced Science, EarlyView.
In this study, we find CD55+ neutrophils show activated NETosis within bone marrow, induce BMSC senescence and osteogenesis inhibition, finally leading to bone aging initiation. Mechanistically, ROS synergizes with the CD55‐driven HIF1α‐PADI4 pathway to promote NETosis.
Yutong Guo, Shengjie Cui, Xi Wen, Yidi Wang, Ben Wu, Yixiang Wang, Yan Gu   +6 more
wiley   +1 more source

Left Ventricular Systolic Function in Long-Term Survivors of Allogeneic Hematopoietic Stem Cell Transplantation

, 2020
Richard Massey, Phoi Phoi Diep, Ellen Ruud, Marta Maria Burman, Anette Borger Kvaslerud, Lorentz Brinch, Svend Aakhus, Lars Gullestad, Jan Otto Beitnes   +8 more
openalex   +2 more sources