Results 131 to 140 of about 395,898 (355)

P402: MUTATIONS IN BONA FIDE ONCOGENES KRAS AND DNMT3A ARE NOT RELATED TO DEPENDENCY IN ESTABLISHED TUMORS, IN PDX MODELS OF ACUTE LEUKEMIA IN VIVO

HemaSphere, 2022
Y. Gao, M. Ghalandary, M. Becker, D. Amend, M. Rothenberg-Thurley, K. Metzeler, I. Jeremias   +6 more
doaj   +1 more source

Prolonged hematopoiesis in a primate bone marrow culture system: characteristics of stem cell production and the hematopoietic microenvironment [PDF]

, 1979
M A Moore, AP Sheridan, TD Allen, TM Dexter   +3 more
openalex   +1 more source

Microneedles From Shape‐Preserving Crosslinked Poly(Vinyl Alcohol) Hydrogels: Minimising Interference in Transdermal Proteomics

Advanced Materials Technologies, EarlyView.
Hydrogel‐forming microneedle patches are developed using shape‐preserving PVA‐PVP hydrogels, with and without chitosan, for minimally invasive transdermal protein biomarker sampling. The optimised patches enable efficient interstitial fluid uptake and proteomic analysis, while minimising interference.
Achmad Himawan, Robert Graham, Fabiana Volpe‐Zanutto, Huanhuan Li, Anjali K. Pandya, Andi Nur Aisyah, Rina Agustina, Juan L. Paris, Juan Dominguez‐Robles, Lalitkumar K. Vora, Andi D. Permana, Christopher J. Scott, Ryan F. Donnelly   +12 more
wiley   +1 more source

Mechanical Interactions Impact the Functions of Immune Cells and Their Application in Immunoengineering

Advanced Therapeutics, EarlyView.
This review covers the mechanical forces experienced by immune cells through cell–cell and cell–extracellular matrix interactions and how these forces influence their receptors and functions. These relationships between forces and cellular functions can be exploited using engineering techniques to modify the physical properties of materials for novel ...
Yu‐Chang Chen, Nghi M. Tran, Kyle H. Vining   +2 more
wiley   +1 more source

Autologous peripheral hematopoietic stem cell transplantation restores hematopoietic function following marrow ablative therapy [PDF]

, 1988
Anne Kessinger, JO Armitage, JD Landmark, DM Smith, DD Weisenburger   +4 more
openalex   +1 more source

Preclinical Evaluation of Thrombopoietin and Flt-3 ligand Treatment [PDF]

, 2003
The hematopoietic system is a cell renewal system in which mature peripheral blood cells with a limited life span are continuously replenished by proliferation and differentiation of lineage-specific progenitor cells derived from scarce pluripotent ...
Hartong, S.C.C. (Simone)
core   +1 more source

Microphysiological Systems in Cancer Research: Advancing Immunotherapy through Tumor Microenvironment‐Integrated Organ‐On‐Chip Models

Advanced Therapeutics, EarlyView.
Emerging microphysiological systems reproduce the spatial, biochemical, and cellular complexity of the tumor microenvironment, surpassing 2D cultures and murine models. By integrating patient‐derived tumors, perfusable vasculature, and immune trafficking, these organ‐on‐chip platforms reveal mechanisms of immune evasion, predict therapeutic responses ...
Fabiana Moresi, Francesco Noto, Jyothsna Vasudevan, Xavier Bisteau, Giulia Adriani, Andrea Pavesi   +5 more
wiley   +1 more source

Retrovirus-mediated gene transfer of human adenosine deaminase: expression of functional enzyme in murine hematopoietic stem cells in vivo. [PDF]

, 1987
Bing Lim, David A. Williams, Stuart H. Orkin   +2 more
openalex   +1 more source

Loss of NR2F6 Protects from Salmonella Typhimurium Infection

Advanced Science, EarlyView.
Loss of nuclear receptor NR2F6 reduces tissue‐resident macrophage populations. Nr2f6‐deficient mice are protected from weight loss and bacterial load during infection with Salmonella Typhimurium. Pro‐inflammatory cytokines and iron levels are altered in infected Nr2f6‐deficient mice.
Johannes Woelk, Christa Pfeifhofer‐Obermair, Julia Benz, Natascha Brigo, Milena Bamberger, Alexeja Kleiter, Martin Hermann, Guenter Weiss, Natascha Hermann‐Kleiter   +8 more
wiley   +1 more source

Synergism between erythropoietin and interleukin-3 in the induction of hematopoietic stem cell proliferation and erythroid burst colony formation [PDF]

, 1988
Giovanni Migliaccio, AR Migliaccio, JW Visser   +2 more
openalex   +1 more source