Results 141 to 150 of about 416,052 (359)

Biocatalytic Nanoregulators Restore Joint Redox‐Immune Homeostasis in Rheumatoid Arthritis

open access: yesAdvanced Science, EarlyView.
Mesenchymal stem cell‐derived extracellular vesicles (EVs) coat ruthenium‐loaded metal‐organic frameworks (Ru@ZrMOF), creating a targeted therapeutic (Ru@ZrMOF/EVs). This platform scavenges ROS, generates oxygen, and polarizes macrophages from M1 to M2, alleviating inflammation, inhibiting pannus, promoting cartilage repair, and downregulating HIF‐1α ...
Xingheng Wang   +7 more
wiley   +1 more source

P093 | ASSESSING HEREDITARY MYELOID NEOPLASMS THROUGH TARGETED NEXT GENERATION SEQUENCING PANEL DESIGN AND DEFINITION OF CLINICAL CRITERIA: A PILOT STUDY

open access: yesHaematologica
Hereditary myeloid neoplasms with germline predisposition represent an emerging category within the spectrum of myelodysplastic and myeloproliferative syndromes.
E. Ronda   +6 more
doaj  

Engineered hematopoietic and immune cells derived from human pluripotent stem cells [PDF]

open access: bronze, 2023
Yun Chang   +5 more
openalex   +1 more source

Impaired bone marrow homing of cytokine-activated CD34+ cells in the NOD/SCID model [PDF]

open access: yes, 2004
The reduced engraftment potential of hematopoietic stem/progenitor cells (HSPCs) after exposure to cytokines may be related to the impaired homing ability of actively cycling cells. We tested this hypothesis by quantifying the short-term horning of human
Ahmed, F   +8 more
core  

BioCNTs Mediated Delivery of Systemically Mobile Small RNAs via Leaf Spray to Control Both Tomato DNA and RNA Viruses

open access: yesAdvanced Science, EarlyView.
A carbon nanotube‐based biopesticide system (BioCNTs) enables efficient delivery and systemic movement of RNAi molecules to control major tomato viruses. By integrating shRNA and tRNA‐like structures (TLS) with BioCNTs, this green and scalable approach achieves long‐term silencing and high antiviral efficacy through simple foliar spraying.
Xuedong Liu   +7 more
wiley   +1 more source

Sabotaged Integral HSC Heterogeneity Underlies Essential Thrombocythemia Development

open access: yesAdvanced Science, EarlyView.
Single‐cell RNA sequencing (scRNA‐seq) maps how distinct driver mutations remodel hematopoietic stem cell (HSC) programs across essential thrombocythemia (ET). Comparative analysis uncovers both shared and subtype‐specific molecular signatures, identifies a triple‐negative (TN)‐associated HSC population enriched with malignant traits, and reveals the ...
Jingyuan Tong   +21 more
wiley   +1 more source

A study of murine bone marrow cells cultured in bioreactors which create an environment which simulated microgravity [PDF]

open access: yes
Previous research indicated that mouse bone marrow cells could be grown in conditions of simulated microgravity. This environment was created in rotating bioreactor vessels. On three attempts mouse cells were grown successfully in the vessels.
Lawless, Brother Desales
core   +1 more source

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