Results 261 to 270 of about 416,052 (359)

Chimeric antigen receptor modified hematopoietic stem cells (CAR-HSCs) arm all immune forces for anti-tumor in mice. [PDF]

Exp Hematol Oncol
Wang T, Liu P, Zhang D, Song Z, Yu M, Feng D, Yu X, Liu N, Tang G, Yang J.   +9 more
europepmc   +1 more source

Sound‐Based Assembly of Magnetically Actuated Soft Robots Toward Enhanced Release of Extracellular Vesicles

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
Magnetic soft robots offer promise in biomedicine due to their wireless actuation and rapid response, but current fabrication methods are complex and have limited cellular compatibility. A new, contactless bioassembly strategy using hydrodynamic instabilities is introduced, enabling customizable, centimeter‐scale robots.
Wei Gao, Riccardo Tognato, Micaela Natta, Elena Della Bella, Alessandro Cianciosi, Tiziano Serra   +5 more
wiley   +1 more source

Microvesicles secreted by CoCl₂-primed mesenchymal stromal cells boost the functionality of hematopoietic stem cells cultured with them. [PDF]

Ann Hematol
Pendse S, Kale V, Vaidya A.
europepmc   +1 more source

Disentangling Coincident Cell Events Using Deep Transfer Learning and Compressive Sensing

Advanced Intelligent Systems, EarlyView.
Overlapping cells during detection distort single‐cell measurements and reduce diagnostic accuracy. A hybrid framework combining a fully convolutional neural network with compressive sensing to disentangle overlapping signals directly from raw time‐series data is presented.
Moritz Leuthner, Rafael Vorländer, Oliver Hayden   +2 more
wiley   +1 more source

A reference model of circulating hematopoietic stem cells across the lifespan with applications to diagnostics. [PDF]

Nat Med
Furer N, Rappoport N, Milman O, Tavor S, Lifshitz A, Bercovich A, Ben-Kiki O, Danin A, Kedmi M, Shipony Z, Lipson D, Meiri E, Yanai G, Shapira S, Arber N, Berdichevsky S, Tyner J, Joshi S, Landau D, Ganesan S, Dusaj N, Chamely P, Kaushansky N, Chapal-Ilani N, Shamir R, Tanay A, Shlush L.   +26 more
europepmc   +1 more source

Circulating hematopoietic stem/progenitor cell subsets contribute to human hematopoietic homeostasis

Pamela Quaranta, Luca Basso‐Ricci, Raisa Jofra Hernández, Guido Pacini, Matteo Maria Naldini, Matteo Barcella, Luca Seffin, Giulia Pais, Giulio Spinozzi, Fabrizio Benedicenti, Carlo Pietrasanta, Jin‐Gyu Cheong, Andrea Ronchi, Lorenza Pugni, Francesca Dionisio, Ilaria Monti, Stefania Giannelli, Silvia Darin, Federico Fraschetta, Graziano Barera, Francesca Ferrua, Valeria Calbi, Marco Ometti, Raffaella Di Micco, Fabio Mosca, Steven Z. Josefowicz, Eugenio Montini, Andrea Calabria, Maria Ester Bernardo, Maria Pia Cicalese, Bernhard Gentner, Ivan Merelli, Alessandro Aiuti, Serena Scala   +33 more
openalex   +1 more source

Randomized Comparison of Cardiotoxicity With 60 Versus 90 mg Daunorubicin in AML Induction Therapy

American Journal of Hematology, EarlyView.
Early cardiac biomarker monitoring in AML induction therapy showed significantly higher hsTnT levels after daunorubicin 90 mg/m2 compared with 60 mg/m2, indicating a dose‐dependent early myocardial effect. ABSTRACT Anthracyclines are an essential component of induction therapy for acute myeloid leukemia (AML), but their optimal dosing and the ...
Stefan Markus Dendorfer, Katharina Schmidt‐Brücken, Michael Kramer, Björn Steffen, Christoph Schliemann, Jan‐Henrik Mikesch, Nael Alakel, Regina Herbst, Mathias Hänel, Maher Hanoun, Martin Kaufmann, Barbora Weinbergerova, Kerstin Schäfer‐Eckart, Tim Sauer, Andreas Neubauer, Andreas Burchert, Claudia D. Baldus, Jolana Mertová, Edgar Jost, Dirk Niemann, Jan Novák, Stefan W. Krause, Sebastian Scholl, Andreas Hochhaus, Gerhard Held, Tomáš Szotkowski, Andreas Rank, Christoph Schmid, Lars Fransecky, Sabine Kayser, Markus Schaich, Frank Fiebig, Annett Haake, Johannes Schetelig, Jan Moritz Middeke, Friedrich Stölzel, Uwe Platzbecker, Christian Thiede, Carsten Müller‐Tidow, Wolfgang E. Berdel, Gerhard Ehninger, Jiri Mayer, Hubert Serve, Martin Bornhäuser, Christoph Röllig   +44 more
wiley   +1 more source

Clusterin drives myeloid bias in aged hematopoietic stem cells by regulating mitochondrial function. [PDF]

Nat Aging
Sun N, Lin CH, Li MY, Wang Y, Chen D, Ren X, Zhang F, Zhang Y.   +7 more
europepmc   +1 more source

Case report: Spontaneous remission of severe aplastic anemia mediated by mutant hematopoietic stem cells evading T-cell attack. [PDF]

Front Immunol
Shiroshita K, Zaimoku Y, Kudo H, Obara N, Hosomichi K, Kano Y, Kobayashi M, Morishita E, Takamatsu H, Toyama T, Nakao S.   +10 more
europepmc   +1 more source

Impact of Mutational Landscape and Burden on RBC Transfusion Response in Patients With Lower‐Risk Myelodysplastic Syndromes (LR‐MDS) in the COMMANDS Study

American Journal of Hematology, EarlyView.
ABSTRACT The COMMANDS trial established luspatercept as a first‐line treatment for anemia in transfusion‐dependent lower‐risk (LR) myelodysplastic syndromes (MDS). Here we report red blood cell (RBC) transfusion response analysis based on somatic mutations profile and disease risk for patients treated with luspatercept or epoetin alfa in the COMMANDS ...
Rami S. Komrokji, Sheida Hayati, Manuel Ugidos, Guillermo Garcia‐Manero, Matteo Giovanni Della Porta, Amer M. Zeidan, Valeria Santini, Uwe Platzbecker, Anita K. Gandhi, Rajasekhar N. V. S. Suragani   +9 more
wiley   +1 more source