Results 161 to 170 of about 3,474 (201)

[Hematoporphyrin derivative-induced tumor fluorescence].

Zeitschrift fur Erkrankungen der Atmungsorgane, 1988
Detection of HpD-sensitized tumour was successful by use of HBO 200 mercury lamp, Argon ion laser, as well as for N2-pumped dye laser. After 20 hours period of HpD application the localization of the Ehrlich ascites tumour in mice was identified macroscopically and by spectroscopy.
E, Knoth, K, König, W, Graszme, W, Dietel, K H, Donnerhacke   +4 more
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Resonance Raman spectra of hematoporphyrin derivative

SPIE Proceedings, 1991
The results of the study of resonance Raman (RR) spectra for the solutions of hematoporphyrin derivative (HPD) are presented. The dependence of spectrum structure on the excitation wavelength and the influence of nature of the solvent on HPD RR lines were studied.
N. G. Golubeva, Litszin Wang
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Bactericidal Effects of Photoradiation Therapy With Hematoporphyrin Derivative

Journal of Infectious Diseases, 1985
Hematoporphyrin derivative (Hpd) localizes selectively in malignant and rapidly metabolizing tissues and undergoes a cytotoxic reaction when exposed to light of a specific wavelength. Hpd has been studied extensively with regard to the diagnosis and treatment of tumors but not with regard to bactericidal activity. This investigation assessed the effect
F R, Venezio, C, DiVincenzo, R, Sherman, M, Reichman, T C, Origitano, K, Thompson, O H, Reichman   +6 more
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Hematoporphyrin Derivative: Chemical Composition, Photochemical and Photosensitizing Properties

1983
“Hematoporphyrin derivative” (HPD) is a product prepared by treating acetylated hematoporphyrin (HPA) with alkali. Acetylated hematoporphyrin is prepared by treating hematoporphyrin dihydrochloride with a mixture of sulphuric acid and acetic acid (Lipson et al. 1961).
J, Moan, S, Sandberg, T, Christensen, S, Elander   +3 more
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Membrane photosensitization by hematoporphyrin and hematoporphyrin derivative.

Progress in clinical and biological research, 1985
HPD-A, the putative active biologic component of HPD, photosensitized lysis of large phosphatidylcholine liposomes and lipid peroxidation in small liposomes with oxygen enhancement ratios from 4 to 5. Unambiguous proof was obtained that this damage was mediated by singlet oxygen.
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Hematoporphyrin‐Derivative and Photoradiation Therapy of Malignant Tumors

Lasers in Surgery and Medicine, 1983
AbstractKodak projectors with #2418 red Corning filters were used as a light source to treat cutaneous and subcutaneous malignancies in five patients who previously had been given hematoporphyrin derivative (HpD). An argon dye laser system was used to treat malignancies in patients who also were given the HpD.
J S, McCaughan, J T, Guy, P, Hawley, W, Hicks, W, Inglis, L, Laufman, E, May, T A, Nims, R, Sherman   +8 more
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Hyperthermal Effects in Phototherapy with Hematoporphyrin Derivative Sensitization

Tumori Journal, 1984
Although the photochemical reaction of hematoporphyrin derivative (HpD) appears to play a major role in cytotoxic activity, the hyperthermal contribution to tumor destruction has not yet been clarified. We investigated its role in the effectiveness of laser photoradiation therapy using MS-2 sarcoma transplanted into the hind pad of BALB/c mice as the ...
E, Melloni, R, Marchesini, H, Emanuelli, G, Fava, L, Locati, G, Pezzoni, G, Savi, F, Zunino   +7 more
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Hematoporphyrin derivative for detection and management of cancer

Cancer, 1967
Hematoporphyrin derivative has been evaluated as a means of detecting malignancy in 121 patients suspected of having cancer. Areas examined included the cervix, vagina, tracheobronchial tree, esophagus, peritoneum and rectum. Dysplastic and neoplastic tissue was identified by red fluorescence whereas nonneoplastic tissue appeared grayish white to black.
R L, Lipson, E J, Baldes, M J, Gray
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Exposure (dose) tables for hematoporphyrin derivative photoradiation therapy

Lasers in Surgery and Medicine, 1984
AbstractTwo sets of tables are presented that permit the rapid determination of (1) milliwatts per centimter2 based upon known site diameter and power output from fiber optic and (2) time of exposure (minutes and seconds) based upon known site diameter and power output from fiber optic.
M W, Berns, G S, Berns, J, Coffey, A G, Wile   +3 more
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A Chromatographic Study of Hematoporphyrin Derivatives

1984
Hematoporphyrin derivative (Hpd), a porphyrin mixture first introduced as a tumorlocalizer by Lipson et al. is the most widely used drug in clinical trials for photoradiation therapy (PRT) of cancer. Furthermore, due to its fluorescence and tumorlocalizing properties, it may be used in cancer diagnosis1–5.
Stein Sommer, Johan Moan, Terje Christensen, Jan F. Evensen   +3 more
openaire   +1 more source