Results 171 to 180 of about 153,280 (319)

An Oxoiron(IV) Complex Supported by an N‐Alkylated Cyclam Ligand System Containing a Pendant Alcohol Moiety

Chemistry – A European Journal, EarlyView.
Depending on the pendant atom present in the N‐alkylated cyclam (1,4,8,11‐tetraazacyclotetradecane) based ligand framework, substantially altered conformations of the non‐heme iron(IV)‐oxo intermediates are revealed. Abstract The effect of a pendant neutral alcohol moiety in the N‐alkylated cyclam (1,4,8,11‐tetraazacyclotetradecane) ligand backbone is ...
Dibya Jyoti Barman, Thomas Lohmiller, Sagie Katz, Michael Haumann, Peter Hildebrandt, Wonwoo Nam, Kallol Ray   +6 more
wiley   +1 more source

The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression

Hepatology, EarlyView., 2022
Loss of NOX4 in HCC tumor cells induces metabolic reprogramming in a Nrf2/MYC‐dependent manner to promote HCC progression. Abstract Background and Aims The NADPH oxidase NOX4 plays a tumor‐suppressor function in HCC. Silencing NOX4 confers higher proliferative and migratory capacity to HCC cells and increases their in vivo tumorigenic potential in ...
Irene Peñuelas‐Haro, Rut Espinosa‐Sotelo, Eva Crosas‐Molist, Macarena Herranz‐Itúrbide, Daniel Caballero‐Díaz, Ania Alay, Xavier Solé, Emilio Ramos, Teresa Serrano, María L. Martínez‐Chantar, Ulla G. Knaus, José M. Cuezva, Antonio Zorzano, Esther Bertran, Isabel Fabregat   +14 more
wiley   +1 more source

Photoinduced Electron Transfer in Ruthenium‐Polypyridyl‐Modified Laccases: Probing Pathways From the Surface to the Metal Centers

Chemistry – A European Journal, EarlyView.
This study investigates photoinduced electron transfer (PIET) within a multicopper oxidase by grafting a ruthenium‐polypyridyl photosensitizer onto different positions on its surface. We uncover alternative ET pathways to the enzyme's copper centers, in which the trinuclear cluster is photoreduced directly without first passing through the Type 1 ...
Iago de Assis Modenez, Annamaria Quaranta, Elise Courvoisier‐Dezord, Yasmina Mekmouche, A. Jalila Simaan, Winfried Leibl, Thierry Tron   +6 more
wiley   +1 more source

Studies on the Control of Hemoglobin Synthesis: The in vitro Stimulating Effect of a 5β-H Steroid Metabolite on Heme Formation in Human Bone Marrow Cells [PDF]

, 1969
Thomas F. Necheles, Uma Shanmugasundaram
openalex   +1 more source

Hybrid Molecules as Efficient Drugs against Multidrug‐Resistant Malaria Parasites

ChemMedChem, EarlyView.
Among hybrid molecules currently developed as antimalarial drug candidates, emoquine‐1 exhibits high activity against all the multidrug‐resistant Plasmodium strains tested up to now, including artemisinin‐resistant quiescent parasites, critical parameters for promising antimalarial drugs. It is also curative in mouse malaria.
Anne Robert, Lucie Paloque, Jean‐Michel Augereau, Flore Nardella, Michel Nguyen, Bernard Meunier, Françoise Benoit‐Vical   +6 more
wiley   +1 more source

Exploring Bonding in Bioinorganic Chemistry: Ab Initio Valence Bond Calculations of Iron(II)‐CO and Iron(IV)‐Oxo Units in Cytochrome P450 under Oriented External Electric Fields

Chemistry–Methods, EarlyView.
Ab initio valence bond calculations under oriented electric fields along the bond axis of Fe(II)‐CO and Fe(IV)‐oxo units in cytochrome P450 enzymes highlight their effectiveness in probing complex bonding characteristics and ligand effects in bioinorganic systems.
Enhua Zhang, Hajime Hirao
wiley   +1 more source

The role of heme in sepsis induced Kupffer cell PANoptosis and senescence. [PDF]

Cell Death Dis
Li T, Adams J, Zhu P, Zhang T, Tu F, Gravitte A, Zhang X, Liu L, Casteel J, Yakubenko V, Williams DL, Li C, Wang X.   +12 more
europepmc   +1 more source

Editorial: Metal Biology Takes Flight: The Study of Metal Homeostasis and Detoxification in Insects

Frontiers in Genetics, 2018
Stephanie E. Mohr, David W. Killilea
doaj   +1 more source

Heme and iron limitation in a GI-tract foundation species leads to a reshuffling of the metalloproteome and a shift toward manganese usage. [PDF]

Front Chem
Rodrigues da Silva R, Larson J, Bothner B, DuBois JL.   +3 more
europepmc   +1 more source

Isolation and Properties of Two Soluble Heme Proteins in Extracts of the Photoanaerobe Chromatium

, 1960
Robert Bartsch, Martin D. Kamen
openalex   +1 more source