Results 181 to 190 of about 187,269 (312)

Crystal Structure and Conformational Dynamics of N─N Bond-Forming Piperazate Synthase. [PDF]

Chembiochem
Pal N, Schröder S, Sahrawat AS, Gruber CC, Hayes MA, Daniel B, Schmidt S, Gruber K.   +7 more
europepmc   +1 more source

Rationales for the Choice of Metals for Super‐Reduced Biological Metal Centers: Cobalt in Cobalamin Versus Nickel in F430

Chemistry – A European Journal, EarlyView.
DFT calculations on porphyrin, corrin, and corphin complexes of cobalt, rhodium, iron, manganese, or nickel, and QM/MM calculations on enzyme models, explore the factors controlling the availably of super‐reduced metal(I) states. True metal(I) states are seen in corrin only for cobalt, in corphin only for nickel, and not at all in porphyrin.
Radu‐Ioan Onija, Sergiu‐Raul Cosma, Adrian M. V. Brânzanic, Radu Silaghi‐Dumitrescu   +3 more
wiley   +1 more source

Russian Dolls of Heme Metabolism in Malaria-Infected Red Blood Cells: Nested Vulnerabilities and Therapeutic Opportunities. [PDF]

Pathogens
Adapa SR, Siddiqui FA, Jiang RHY.
europepmc   +1 more source

Role of selenium in the pathophysiology of cardiorenal anaemia syndrome

ESC Heart Failure, Volume 12, Issue 2, Page 770-780, April 2025.
Abstract Chronic kidney disease (CKD) and cardiovascular disease (CVD) have multiple bidirectional mechanisms, and anaemia is one of the critical factors that are associated with the progression of the two disorders [referred to as cardiorenal anaemia syndrome (CRAS)].
Shigeyuki Arai, Minoru Yasukawa, Shigeru Shibata   +2 more
wiley   +1 more source

Electron Bifurcation Arises from Emergent Features of Multicofactor Enzymes. [PDF]

ACS Omega
Wójcik-Augustyn A, Bujnowicz Ł, Osyczka A, Sarewicz M.   +3 more
europepmc   +1 more source

Increased calcification by erythrophagocytosis in aortic valvular interstitial cells

ESC Heart Failure, Volume 12, Issue 2, Page 1469-1473, April 2025.
Abstract Background Calcific aortic valve disease (CAVD) progresses over time to severe aortic stenosis and eventually heart failure. Recent evidence indicates that intraleaflet haemorrhage (ILH) strongly promotes CAVD progression. However, it remains poorly understood how it mechanistically contributes to valvular calcification.
Zihan Qin, Magnus Bäck, Anders Franco‐Cereceda, Sven‐Christian Pawelzik   +3 more
wiley   +1 more source

Transport of cytochrome c heme lyase [PDF]

, 1983
Neupert, Walter, Hennig, Bernd, Köhler, Helmut, Schweyen, Rudolf J.   +3 more
core   +1 more source

Dapagliflozin alleviates high‐fat‐induced obesity cardiomyopathy by inhibiting ferroptosis

ESC Heart Failure, Volume 12, Issue 2, Page 1358-1373, April 2025.
Abstract Aim: Dapagliflozin (Dapa) is a novel hypoglycaemic agent with multiple cardiovascular protective effects, and it is widely used in treatment of heart failure patients, but whether it can improve obese phenotype of heart failure and its mechanism is still unclear.
Di Chen, Jiahao Shi, Yue Wu, Lizhu Miao, Zilin Wang, Yixuan Wang, Siwei Xu, Yu Lou   +7 more
wiley   +1 more source

A cell-nonautonomous heme acquisition pathway enables erythroid hemoglobinization under stress. [PDF]

Science
Belot A, Rock A, Dutt S, Haemmerle G, Maros A, Yuan X, Otsuru S, Bodine D, Hamza I.   +8 more
europepmc   +1 more source

Mechanistic Dichotomy in Enantioselective Pd‐Catalyzed Alkylation of Pyrroles With Diazoesters

European Journal of Organic Chemistry, EarlyView.
Ligand‐controlled mechanistic divergence controls the Pd‐catalyzed asymmetric alkylation of pyrroles with diazoesters. While bipyridine ligands promote a conventional metal‐carbene pathway, bipyridine‐N,N′‐dioxide ligands redirect catalysis through electrophilic CH metalation before carbene transfer.
Vladimir Yu. Vaganov, Yasuaki Fukazawa, Svyatoslav M. Pechenkin, Vladimir S. Hein, Aleksandr E. Rubtsov, Andrei V. Malkov   +5 more
wiley   +1 more source