Results 171 to 180 of about 232,755 (310)

Increased calcification by erythrophagocytosis in aortic valvular interstitial cells

ESC Heart Failure, Volume 12, Issue 2, Page 1469-1473, April 2025.
Abstract Background Calcific aortic valve disease (CAVD) progresses over time to severe aortic stenosis and eventually heart failure. Recent evidence indicates that intraleaflet haemorrhage (ILH) strongly promotes CAVD progression. However, it remains poorly understood how it mechanistically contributes to valvular calcification.
Zihan Qin, Magnus Bäck, Anders Franco‐Cereceda, Sven‐Christian Pawelzik   +3 more
wiley   +1 more source

Value of functional iron parameters in diagnostic re-assessment of MPN: refinement of iron-deficiency markers by zinc protoporphyrin (ZPP). [PDF]

Ann Hematol
Manz K, Kobrosly M, Crodel CC, Al-Ali H, Isfort S, Kleppe D, Neubert M, Schnöder TM, Rogalski I, Jilg S, Stauch T, Hoffmann W, Krüger WH, Krönke J, Hochhaus A, Homann C, Heidel FH.   +16 more
europepmc   +1 more source

Dapagliflozin alleviates high‐fat‐induced obesity cardiomyopathy by inhibiting ferroptosis

ESC Heart Failure, Volume 12, Issue 2, Page 1358-1373, April 2025.
Abstract Aim: Dapagliflozin (Dapa) is a novel hypoglycaemic agent with multiple cardiovascular protective effects, and it is widely used in treatment of heart failure patients, but whether it can improve obese phenotype of heart failure and its mechanism is still unclear.
Di Chen, Jiahao Shi, Yue Wu, Lizhu Miao, Zilin Wang, Yixuan Wang, Siwei Xu, Yu Lou   +7 more
wiley   +1 more source

Impact of heme on the therapeutic efficacy of anti-CD20 antibodies. [PDF]

J Biol Chem
Marey-Jarossay A, Tavares A, Lacombe RV, Delcourt H, Lecerf M, Cruz-Aguirre AS, Lassouani TH, Gilardin L, Tareste D, Kaveri SV, Lacroix-Desmazes S, Siberil S, Teillaud JL, Dimitrov JD.   +13 more
europepmc   +1 more source

Trends in Structural and Spectroscopic Signatures of Iron(II) Complexes Supported by Systematically Varied Tetra‐N‐Heterocyclic Carbene Macrocycles

European Journal of Inorganic Chemistry, EarlyView.
The effects of ligand ring size and peripheral substitution on geometric and electronic structures as well as electrochemical and spectroscopic properties of a family of iron(II) complexes with macrocyclic tetracarbene ligands, often called organometallic heme analogues, have been analyzed, to provide structure/property correlations as a basis for ...
Isabelle Becker, Allyssa A. Massie, Xian Zhang, Massimiliano Morganti, Alisa Denisiuk, Marcel E. Baumert, Sebastian Dechert, Franc Meyer   +7 more
wiley   +1 more source

A cell-nonautonomous heme acquisition pathway enables erythroid hemoglobinization under stress. [PDF]

Science
Belot A, Rock A, Dutt S, Haemmerle G, Maros A, Yuan X, Otsuru S, Bodine D, Hamza I.   +8 more
europepmc   +1 more source

Mechanisms of cell protection by heme oxygenase-1.

Annual Review of Pharmacology and Toxicology, 2010
R. Gozzelino, V. Jeney, M. Soares
semanticscholar   +1 more source

1,1‐Disubstituted Vinylbromides: Versatile Building Blocks for the Synthesis of Nitrogen‐Containing Heterocycles

European Journal of Organic Chemistry, EarlyView.
1,1‐Disubstituted vinylbromides are key intermediates for constructing nitrogen‐containing heterocycles. This review provides an overview of the synthetic applications of 1,1‐disubstituted vinylbromides and summarizes recent developments in reaction methodologies, mechanistic insights, and the structural diversity of N‐heterocyclic compounds accessible
Anne Westermeyer, Jun Fang, Chonghuo Liu, Guillaume Lefèvre, Gérard Guillamot, Phannarath Phansavath, Virginie Ratovelomanana‐Vidal   +6 more
wiley   +1 more source

A Review on Carbon‐Based and Metal‐Based Anode Materials of Microbial Fuel Cells

Energy Science &Engineering, EarlyView.
Reviews a wide range of anode materials used in microbial fuel cells (MFCs) and evaluates their performance and suitability for scalable energy recovery from wastewater. Defines the essential characteristics of an ideal anode, including high surface area, excellent electrical conductivity, strong biocompatibility, and cost‐effectiveness, while ...
Md. Hamidur Rahman, A. N. M. Mominul Islam Mukut   +1 more
wiley   +1 more source

Engineering a Hybrid Heme Pathway for Hemoprotein‐Based Dye‐Decolorizing Peroxidase in Escherichia coli

Food Bioengineering, EarlyView.
In this study, the heme content and enzymatic activity of the RhDypB mutant strain RhDypB‐R80 were enhanced through optimized heme uptake and pathway integration. This engineered host presents a promising platform for hemoprotein engineering and holds potential for applications in controlling mycotoxin contamination in food products.
Yue Sun, Jin‐Ping Chen, Nan‐Kai Wang, Chang Su, Heng Li, Jin‐Song Gong, Zheng‐Hong Xu, Jin‐Song Shi   +7 more
wiley   +1 more source