Results 201 to 210 of about 232,755 (310)

A Personal Perspective on Metalloprotein Structure and the Future of Macromolecular X‐Ray Crystallography

Journal of the Chinese Chemical Society, EarlyView.
While X‐ray crystallography has been the primary method for determining the structures of metalloproteins, cryoEM has taken over this role, illustrated by [4Fe4S]‐cluster containing proteins deposited in the Protein Data Bank. What will be the role for X‐ray crystallography as cryoEM and machine learning methods dominate the initial structural analysis?
Douglas C. Rees
wiley   +1 more source

Heme, copper, and a new way to kill cancer cells. [PDF]

EXO
Zhao X, Zhuang L, Gan B.
europepmc   +1 more source

Binuclear Copper‐Dependent Oxidative Enzymes Involved in Fungal Natural Product Modifications

Journal of the Chinese Chemical Society, EarlyView.
This article summarizes recent biochemical characterizations of a new enzyme family named by the authors as binuclear copper‐dependent oxidative enzymes (BiNCOs). Found in fungal natural product biosynthesis, BiNCOs catalyze diverse CH functionalization reactions, including C(sp3)H halogenation, C(sp3)H hydroxylation, C(sp3)O macrocyclization, and ...
Chen‐Yu Chiang, Masao Ohashi, Yi Tang
wiley   +1 more source

Visualizing the mechanism of quinol oxidation and inhibition of a <i>bd</i>-type oxidase using cryo-EM. [PDF]

Sci Adv
van der Velden TT, Kayastha K, Pelser F, Brünle S, Jeuken LJC.   +4 more
europepmc   +1 more source

Deep learning‐assisted design of nanozyme for immune regulation

Journal of Intelligent Medicine, EarlyView.
Overview of nanozyme‐based strategies for inflammatory bowel disease therapy, featuring metal‐based and non‐metallic nanozymes classified by structure, alongside multifunctional and engineered probiotic‐based nanozymes classified by function. Abstract Inflammatory bowel disease (IBD), with rising global incidence and disease burden, is a multifactorial
Ke Chen, Si Sun, Shaofang Zhang, Huanhuan Qiao   +3 more
wiley   +1 more source

Accuracy of Various Methods for the Surveillance of Hospital-acquired Venous Thromboembolism in a Children's Hospital. [PDF]

Pediatr Qual Saf
Huibonhoa RMT, Faustino EVS, Burkiewicz K, Oelkers P, Ravishankar S, Tripathi S.   +5 more
europepmc   +1 more source

Care transition from a pediatric intestinal rehabilitation program to adult care and the risk of all‐cause mortality: A retrospective cohort study

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Background As patients with intestinal failure reach adulthood, transitioning to adult care remains challenging because of a lack of specialized programs. This study evaluated outcomes of patients who transitioned care from a pediatric intestinal rehabilitation program.
Gillian R. Goddard, Stephanie Oliveira, Crystal Slaughter, Kim Klotz, Marilyn Stoops, Julie Schletker, Jackie Wessel, Michael Helmrath, Samuel Kocoshis, Monique Goldschmidt, Paul W. Wales   +10 more
wiley   +1 more source

Hole migration in cytochrome P450. [PDF]

QRB Discov
Gray H, Winkler J.
europepmc   +1 more source