Results 151 to 160 of about 42,175 (244)

Author Correction: Malaria parasite heme biosynthesis promotes and griseofulvin protects against cerebral malaria in mice. [PDF]

open access: yesNat Commun
Chandana M   +8 more
europepmc   +1 more source

The host transcriptional response to Candidemia is dominated by neutrophil activation and heme biosynthesis and supports novel diagnostic approaches. [PDF]

open access: yesGenome Med, 2021
Steinbrink JM   +10 more
europepmc   +1 more source

Ferroptosis: Newly Emerged Regulator for Human Disease

open access: yesMedComm, Volume 7, Issue 9, September 2026.
Ferroptosis is a key regulated cell death pathway closely involved in cancers, neurodegenerative disorders, acute organ injuries, and cardiovascular and chronic metabolic diseases, representing a promising therapeutic target for diverse human illnesses.
Dandan Xiao   +4 more
wiley   +1 more source

Oxidative and Antioxidant Systems in Ferroptosis of Cancer: Mechanisms, Regulations, and Therapeutic Targeting

open access: yesMedComm – Oncology, Volume 5, Issue 3, September 2026.
Ferroptosis is governed by the balance between reactive oxygen species (ROS)‐driven lipid peroxidation and a multi‐tiered antioxidant network. ROS sources include mitochondrial electron transport chain, voltage‐dependent anion channels, NADPH oxidases, and endoplasmic reticulum‐resident oxidoreductases, while antioxidant defenses span the primary GSH ...
Deepak K   +5 more
wiley   +1 more source

Nitric Oxide in Cancer: Mechanisms, Dual Role, and Therapeutic Strategies

open access: yesMedComm – Oncology, Volume 5, Issue 3, September 2026.
Nitric oxide exerts concentration‐dependent dual roles in cancer, functioning as either a tumor promoter or suppressor. This review comprehensively examines NO's multifaceted regulation of tumor biology, including S‐nitrosylation signaling, metabolic reprogramming, immunemodulation, and therapy resistance, and highlights emerging therapeutic strategies
Jia Shao   +8 more
wiley   +1 more source

Resveratrol: Advance on the Most Recent Research From 2021 to 2025

open access: yesPhytochemicals in Food and Medicine, Volume 1, Issue 3, September 2026.
This review summarizes recent progress in resveratrol research (2021–2025), highlighting its natural sources, bioactivities, clinical evidence, and safety profiles. Resveratrol exerts multi‐target effects through the regulation of oxidative stress, inflammation, mitochondrial function, and gut microbiota.
Quanyong Wu   +4 more
wiley   +1 more source

Evolutionary insights into bilin biosynthesis: Functional characterization of pre‐PcyA enzymes

open access: yesProtein Science, Volume 35, Issue 9, September 2026.
Abstract Biosynthesis of the linear tetrapyrrole phycocyanobilin (PCB) by the ferredoxin‐dependent bilin reductase (FDBR) PcyA is essential for light‐harvesting and regulatory processes in diverse photosynthetic organisms, yet its evolutionary origins are not fully understood. PcyA evolved from pre‐PcyA proteins found in diverse bacteria.
Federica Frascogna   +3 more
wiley   +1 more source

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