Results 171 to 180 of about 42,175 (244)

Erythroid Differentiation and Heme Biosynthesis Are Dependent on a Shift in the Balance of Mitochondrial Fusion and Fission Dynamics. [PDF]

open access: yesFront Cell Dev Biol, 2020
Gonzalez-Ibanez AM   +7 more
europepmc   +1 more source

PIEZO1 is Required for Acute Myeloid Leukemia Progression and Leukemia Stem Cell Maintenance via HIF1A‐SLC7A11 Axis‐Mediated Ferroptosis Defense

open access: yesAdvanced Science, Volume 13, Issue 44, 7 August 2026.
This study identifies the mechanosensor PIEZO1 as a key factor in promoting acute myeloid leukemia progression and uncovers a ferroptosis defense system mediated by PIEZO1‐HIF1A‐SLC7A11 axis that is essential for leukemia stem cell maintenance. This ferroptotic defense system may represent a unique vulnerability for leukemia stem cells, providing a ...
Tiantian Zhang   +10 more
wiley   +1 more source

Mapping Steroidogenic Perturbations Under Endocrine Disruptor Mixtures Across Demographic Subgroups: Structural and Metabolomic Insights

open access: yesAdvanced Science, Volume 13, Issue 46, 17 August 2026.
Population‐scale EDC–hormone association mapping among 4255 participants across demographic subgroups identifies phthalate metabolites as the most consistent signals associated with lower testosterone‐related markers in males. Integrative mechanistic validation prioritizes MCPP as a key phthalate metabolite linked to CYP17A1‐centered disruption of ...
Yanling Chen   +14 more
wiley   +1 more source

Nutritional Composition of African Catfish (Clarias gariepinus) in Ghana: Effects of Culture Conditions, Feed and Processing

open access: yesAquaculture, Fish and Fisheries, Volume 6, Issue 4, August 2026.
This review synthesizes current evidence on the nutritional composition of African catfish (Clarias gariepinus), with emphasis on Ghanaian aquaculture. The species is a valuable source of high‐quality protein, essential amino acids, minerals and vitamins, although lipid composition varies widely.
Amy Atter   +15 more
wiley   +1 more source

Uncovering Cystic Fibrosis Carrier: Insights From a Heterozygous CFTR‐F508del Rabbit Model

open access: yesInternational Forum of Allergy &Rhinology, Volume 16, Issue 8, Page 788-796, August 2026.
ABSTRACT Background Chronic rhinosinusitis (CRS) is a heterogeneous inflammatory disorder frequently associated with impaired mucociliary clearance and bacterial infection. Individuals carrying a single cystic fibrosis transmembrane conductance regulator (CFTR) mutation exhibit partial CFTR dysfunction and are increasingly recognized as being at risk ...
Do‐Yeon Cho   +9 more
wiley   +1 more source

5-Aminolevulinate synthase catalysis: The catcher in heme biosynthesis. [PDF]

open access: yesMol Genet Metab, 2019
Stojanovski BM   +5 more
europepmc   +1 more source

The power of many: when genetics met yeasts and high‐throughput

open access: yesBiological Reviews, Volume 101, Issue 4, Page 1662-1682, August 2026.
ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley   +1 more source

Overcoming Radiation Resistance: Ferroptosis Induction to Sensitize Solid Tumors to Radiation Therapy

open access: yesCancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Radiation therapy (RT) is a mainstay of treatment for a myriad of cancers, often utilized for tumors that are unable to be resected, as well as an adjunct to surgery and chemotherapy. Unfortunately, many cancers are resistant to RT‐induced damage and subsequent cell death.
Joseph Carmicheal   +4 more
wiley   +1 more source

Synthetic Sinapates: Antifungal, Molecular Docking, and ADMET Studies

open access: yesChemistry &Biodiversity, Volume 23, Issue 8, August 2026.
ABSTRACT The increasing incidence of diseases resulting from fungal infections is due to the high morbidity and mortality associated with these microorganisms. Sinapic acid is a plant‐derived phenolic compound with antifungal activity. Therefore, in this study, a collection of eleven sinapates (1‐11) was prepared and the antifungal activity of these ...
Fernando Emanuel de Sousa Ferreira   +7 more
wiley   +1 more source

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