Results 191 to 200 of about 732,679 (273)

New FLU mutant alleles point to new insights into singlet oxygen‐mediated signal transduction

open access: yes
New Phytologist, Volume 252, Issue 4, Page 1354-1356, November 2026.
Bernhard Grimm
wiley   +1 more source

Spray‐Dried Engineered Escherichia coli Whole‐Cell Biocatalysts Enable Cell Recycling and In Vivo α‐Ketoglutarate and NADPH Regeneration for Efficient Codeine Manufacture

open access: yesBiotechnology and Bioengineering, Volume 123, Issue 10, Page 2629-2642, October 2026.
ABSTRACT A recombinant whole‐cell biocatalytic approach provides several advantages over isolated enzymes, such as improved enzyme stability, in vivo cofactor regeneration, and the facilitation of cascade reactions within a single cell. Whole‐cell biocatalysis has gained attention in medicinal opioid production, due to its technical and economic ...
Ali Jahanian   +4 more
wiley   +1 more source

Interplay Between Epigenetics and Reactive Oxygen Species in Tumor Radioresistance: Mechanisms and Therapeutic Strategies for Radiotherapy

open access: yesCancer Medicine, Volume 15, Issue 10, October 2026.
ABSTRACT Radiotherapy efficacy is constrained by tumor radioresistance, which arises in part from the interplay between reactive oxygen species (ROS) and epigenetic regulation. This review systematically synthesizes the bidirectional “epigenetics‐ROS interactive network” that governs tumor radiosensitivity. We propose that this network operates through
Zhengmao Yang   +5 more
wiley   +1 more source

Phytochemistry, Pharmacological Potential, and Future Prospects of Abietane‐Type Diterpenoids From Salvia rosmarinus

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
The review delves into the findings on abietane diterpenes from Salvia rosmarinus. It comprises the phytochemistry, biological activities, biosynthesis, degradation studies, semisynthesis, and pharmacokinetic studies of these compounds. The potential of these compounds for future development has also been highlighted.
Rida Siddiqui, Vipin Singh, Kapil Dev
wiley   +1 more source

Chemical Composition, Antioxidant and Antimicrobial Activities of Moroccan Equisetum ramosissimum Essential Oil and Butanolic Extract

open access: yesChemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Moroccan Equisetum ramosissimum essential oil showed a distinct pulegone‐eudesmol‐rich profile and strain‐dependent antimicrobial activity, including against resistant isolates. The butanolic extract displayed stronger antioxidant activity in DPPH and β‐carotene bleaching assays, while docking suggested plausible interactions with selected microbial ...
Saida Sissi   +7 more
wiley   +1 more source

Cordycepin Regulates the Nrf2/Hmox1 Signaling Pathway to Inhibit Ferroptosis and Improve AKI‐CKD

open access: yesCell Biochemistry and Function, Volume 44, Issue 10, October 2026.
ABSTRACT Cordycepin (COR) exerts pharmacological effects in various diseases, yet its role in tissue repair following acute kidney injury (AKI) remains to be fully elucidated. This study aimed to investigate whether COR delays the progression from acute kidney injury to chronic kidney disease (AKI‐CKD) and to explore its underlying mechanisms.
Luming Xi   +4 more
wiley   +1 more source

Metabolomics Analysis Revealed That SXZ Ameliorates Cognitive Impairment in Naturally Aged Rats by Promoting Glutathione Metabolism and Inhibiting the Ferroptosis Pathway

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
In aged rats, 6‐month SXZ treatment reversed spatial memory deficits and preserved hippocampal integrity. Mechanistic assays show that SXZ promotes glutathione metabolism and inhibits ferroptosis via p53/SLC7A11/GPX4 and Keap1/Nrf2/HO‐1 pathways. SXZ is a novel neuroprotective agent against age‐related cognitive decline.
Mengya Liu   +6 more
wiley   +1 more source

Population Genomic Analysis in Wild Medaka Populations: Identifying Candidate Loci for Balancing Selection

open access: yesEcology and Evolution, Volume 16, Issue 10, October 2026.
We explored genomic signatures of balancing selection and selective sweep in the northern medaka, Oryzias sakaizumii in Japan by performing whole‐genome resequencing of wild individuals. In addition, we reevaluated the population genetic structure and admixture of Oryzias latipes and O.
Shingo Fujimoto   +9 more
wiley   +1 more source

Phytochemicals and Health Benefits of American Ginseng (Panax quinquefolius L.): Current Knowledge and Future Perspectives

open access: yesFood Safety and Health, Volume 4, Issue 4, Page 762-770, October 2026.
This review summarizes the chemical constituents and functional characteristics of American ginseng, aiming to provide references for its development and application. ABSTRACT American ginseng, a perennial herbaceous plant, is recognized for its significant medicinal properties and has attracted considerable attention due to its diverse phytochemical ...
Wei Geng   +5 more
wiley   +1 more source

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