Results 191 to 200 of about 42,175 (244)
Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.Chlorfenapyr reduces testicular weight, sperm quality, and reproductive hormones. This study highlights that RA within chitosan nanoparticles (RA‐CHNPs) are superior to Rosmarinic acid in mitigating CFP‐induced testicular damage. RA within chitosan nanoparticles leads to the reduction of NF‐κB and NLRP3 expression in seminiferous tubules and activates ...
Ahmad Najem Alshammari +6 more
wiley +1 more source
Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.Methotrexate (MTX) altered oxidative stress parameters, reduced Nrf2 and HO‐1 protein expression, increased intrinsic apoptosis‐associated protein markers, and decreased cell viability in OVCAR‐3 cells. Antioxidant co‐treatment partially modulated these protein responses and oxidative stress parameters.
Oya Korkmaz
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Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 4, August 2026.ABSTRACT Background Sarcopenia is a progressive skeletal muscle disorder prevalent in older adults, yet its role as a risk factor for acute postoperative cognitive decline—an early manifestation within the spectrum of perioperative neurocognitive disorders (PND)—remains underexplored.
Xingming Tang +9 more
wiley +1 more source
Metabolic Regulation of Macrophages in Health and Disease
MedComm, Volume 7, Issue 8, August 2026.Extracellular metabolites drive metabolic rewiring of glucose, lipid, and amino acid pathways in macrophages, steering their polarization toward pro‐ or anti‐inflammatory phenotypes and shaping a wide range of disease processes. Macrophages from different tissues display distinct metabolic signatures, and therapeutic strategies that target these ...
Shan Huang +6 more
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Macrophage: Biological Functions, Diseases, and Therapeutic Targets
MedComm, Volume 7, Issue 8, August 2026.Macrophages are sentinel innate immune cells that arise from embryonic precursors and bone marrow monocytes, displaying a functional continuum that transcends the classical M1 (pro‐inflammatory)/M2 (anti‐inflammatory) dichotomy. Under homeostatic conditions, balanced M1/M2 polarization preserves tissue integrity by coordinating immune surveillance ...
Bihang Sun +4 more
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MedComm, Volume 7, Issue 8, August 2026.Mycobacterium tuberculosis–host interactions and infection outcomes. Following initial infection, alveolar macrophages phagocytose the pathogen, prompting the recruitment of innate immune cells including neutrophils, NK cells, and interstitial macrophages.
Xiaojuan Zhang +3 more
wiley +1 more source
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Biological Chemistry, 2022
Abstract Heme (protoheme IX) is an essential cofactor for a large variety of proteins whose functions vary from one electron reactions to binding gases. While not ubiquitous, heme is found in the great majority of known life forms. Unlike most cofactors that are acquired from dietary sources, the vast majority of organisms that utilize ...
Harry A. Dailey, Amy E. Medlock
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Abstract Heme (protoheme IX) is an essential cofactor for a large variety of proteins whose functions vary from one electron reactions to binding gases. While not ubiquitous, heme is found in the great majority of known life forms. Unlike most cofactors that are acquired from dietary sources, the vast majority of organisms that utilize ...
Harry A. Dailey, Amy E. Medlock
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Heme biosynthesis in the heart
Biochemical Pharmacology, 1982The rates of biosynthesis of heme a and heme b in hearts of fed and fasted rats were measured using an isolated heart perfusion system. delta-Aminolevulinic acid synthetase activity was decreased in hearts of fasted rats to about 30% of values in hearts obtained from fed rats.
R, Sedman +3 more
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