Results 201 to 210 of about 732,679 (273)

Integrating Transcriptomic and Proteome Analysis to Understand Muscle Qualities and Related Regulatory Factors of Holstein Beef Under Transportation Stress

open access: yesFood Science &Nutrition, Volume 14, Issue 10, October 2026.
In Holstein steers subjected to 15 h of long‐distance transportation, beef exhibited marked differences in meat quality, myofibrillar structure, and flavor components compared with cattle slaughtered without prior transport. These differences included significantly increased shear force, water loss rate, and drip loss, shortened sarcomere length, and ...
Zhaomin Lei   +5 more
wiley   +1 more source

THE RÔLE OF ACETIC ACID IN THE BIOSYNTHESIS OF HEME

open access: yesJournal of Biological Chemistry, 1950
N S, RADIN, D, RITTENBERG, D, SHEMIN
openaire   +2 more sources

Markers of Systemic Metabolic Dysfunction in Vitiligo and Their Potential Role in Disease Pathogenesis: A Narrative Review

open access: yesHealth Science Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background Vitiligo is a chronic autoimmune disease characterized by the progressive destruction of melanocytes, resulting in depigmented skin macules. While traditionally viewed as a cutaneous disorder driven by a specific CD8+ T cell‐mediated interferon‐γ (IFN‐γ) signature, emerging research suggests that vitiligo may be a systemic condition
Federica Papaccio   +2 more
wiley   +1 more source

Rev‐erb‐α in Skeletal Muscle Adaptation: Integrating Circadian Control Mechanisms and Exercise Dynamic Responses

open access: yesJournal of Cellular Physiology, Volume 241, Issue 10, October 2026.
ABSTRACT Circadian rhythms orchestrate a host of biological processes in a time‐dependent manner to maintain homeostasis in response to exercise. Within this framework, Rev‐erb‐α, an intracellular nuclear receptor and transcriptional regulator, transcends its role in circadian rhythms to drive myogenesis, muscle remodeling, primary metabolism, and ...
Ivo Vieira de Sousa Neto   +7 more
wiley   +1 more source

Bacterial Cytochrome C Orchestrates Larval Metamorphosis Through Bioelectrical Control of Extracellular Vesicles Biogenesis

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 10, October 2026.
The ccmH‐encoded CytC serves as a bioelectrical driver, facilitating EV production and orchestrating biofilm‐mediated larval metamorphosis. ABSTRACT Beyond the well‐established roles in biomedical processes, extracellular vesicles (EVs) from Gram‐negative bacteria are now identified as potent inducers of larval metamorphosis in marine invertebrates, a ...
Yu Tao   +6 more
wiley   +1 more source

CRISPR/Cas9‐Mediated Correction of the SLC25A38 Mutation in a Patient With Sideroblastic Anemia

open access: yesThe Journal of Gene Medicine, Volume 28, Issue 10, October 2026.
In this study, the identity of fibroblast cells isolated from the patient was identified using several methods. Then, the sgRNA3‐pX459 plasmid together with ssODN was transfected into fibroblast cells with a transfection efficiency of 49.64%. Finally, the entry of ssODN donor into fibroblast cells was confirmed using PCR‐RFLP and PAGE methods. ABSTRACT
Shokoufeh Yazdanparast   +4 more
wiley   +1 more source

Multifaceted Suppression of Staphylococcal Virulence Phenotypes: In Vitro Study of a Cellular Status With Reduced Agr Activity and Impaired Biofilm

open access: yesMicrobiologyOpen, Volume 15, Issue 5, October 2026.
Finding of in vitro S. aureus status with reduced Agr activity and impaired biofilm. ABSTRACT Anti‐quorum sensing (QS) therapy has been focused on to reduce the virulence of pathogenic bacteria. However, there is a risk that suppression of the staphylococcal QS Agr system might promote biofilm formation.
Nghi Bao Nguyen   +4 more
wiley   +1 more source

First Report of blaCTX‐M‐15 in a Marine Thermotolerant Enterobacter Isolate From Bangladesh: Genomic Insights Into Halotolerance and Antimicrobial Resistance

open access: yesMicrobiologyOpen, Volume 15, Issue 5, October 2026.
Marine‐derived Enterobacter kobei, exhibiting thermotolerance and salt tolerance, is ESBL‐producing and harbors AMR genes (blaCTX‐M‐15, qnrS1) and mobile genetic elements, indicating environmental spread of antimicrobial resistance. ABSTRACT Marine ecosystems are becoming important reservoirs for antimicrobial resistance (AMR). However, genomic data on
Md. Arifur Rahman   +5 more
wiley   +1 more source

Osteomyelitis: Epidemiology, Classification, Pathophysiology, Clinical Features, Diagnosis, and Management

open access: yesMedComm, Volume 7, Issue 10, October 2026.
The immunosuppressive in OM Staphylococcus aureus employs multiple physical barriers to evade host immunity during skeletal infection, including biofilm formation on implant surfaces and necrotic bone tissues, invasion into the osteocyte lacuno‐canalicular network (OLCN), intracellular persistence within osteoblasts, osteoclasts, and osteocytes, and ...
Qingqiang Lei   +7 more
wiley   +1 more source

Ischemic Stroke and Traumatic Brain Injury: Epidemiology, Molecular Pathways, and Emerging Therapies

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Schematic overview of secondary brain injury after ischemic stroke and traumatic brain injury. Both conditions trigger endothelial cell dysfunction, pericyte contraction, and upregulated AQP4 expression in astrocytic end‐feet, leading to blood–brain barrier disruption.
Mengzhao Feng   +7 more
wiley   +1 more source

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