Results 211 to 220 of about 732,679 (273)

Fumarate and Its Esters: Physiology, Pathology, Molecular Mechanisms, Diseases, and Therapy

MedComm, Volume 7, Issue 10, October 2026.
Fumarate is an endogenous immunometabolite that regulates metabolism, redox homeostasis, and inflammation. Although fumaric acid esters (FAEs) share several molecular targets with fumarate, their distinct physicochemical properties confer unique biological activities and therapeutic applications.
Peng Zhu, Mengling You, Yi Zeng, Jinglin Zhang, Si Chen, Rong Rong, Xiaobo Xia   +6 more
wiley   +1 more source

Snapshots From the Catalytic Landscape of Chalcone Isomerase

Plant Direct, Volume 10, Issue 10, October 2026.
ABSTRACT Chalcone isomerase (CHI) catalyzes the cyclization of three‐ring scaffolds of flavonoids, a class of plant‐based natural products important for nutrition and disease prevention. A persistent question has been whether the enzyme uses protein dynamics to facilitate conformational rearrangements of substrates within the active site.
Jason R. Burke, Matthew A. Rangel, Vanessa I. Vasquez Meza, Hailey N. Mims, Thomas O. Darko, Kelwyn Ixcoy, Alfredo Ruiz Rivera, Jason Zhang, Emma R. Wolf‐Saxon, Chad C. Moorman   +9 more
wiley   +1 more source

Universal and Lineage‐Specific Patterns in the Distribution of ECOD Domain Homology Groups Across Superkingdoms

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 10, Page 1644-1657, October 2026.
ABSTRACT Proteins are built from modular domains that serve as fundamental units of structure and evolution. While individual domains have been extensively cataloged, their collective distribution across the lineages of life has remained poorly resolved.
Rui Guo, Jimin Pei, Jing Zhang, Qian Cong, Nick V. Grishin, R. Dustin Schaeffer   +5 more
wiley   +1 more source

Persistence of PPO mutations and dynamics of Amaranthus palmeri resistance to PPO‐inhibitor herbicides in a decade

Pest Management Science, Volume 82, Issue 10, Page 10185-10191, October 2026.
Over a decade, Arkansas Amaranthus palmeri populations maintained resistance to PPO‐inhibiting herbicides. PPO2 mutations relate to shifts in herbicide resistance patterns over time. Abstract BACKGROUND Amaranthus is a highly troublesome weed genera globally.
Prakriti Dhaka, Gulab Rangani, Aimone Porri, Ingo Meiners, Robert C Scott, Nilda Roma‐Burgos   +5 more
wiley   +1 more source

Macrophages Contribute to Pulmonary Hypertension Associated With Sickle Cell Disease

Pulmonary Circulation, Volume 16, Issue 4, October 2026.
This study investigated proteomic and metabolomic differences in pulmonary macrophages and the lung microenvironment to determine molecular pathways involved in Sickle Cell Disease associated pulmonary hypertension. We concluded that macrophages play a critical role in disease pathology by decrease pulmonary arterial muscularization. ABSTRACT Pulmonary
Christina Lisk, Francesca Cendali, Natalie Westover, Delaney Swindle, Daniel Colon Hidalgo, Caitlin Lewis, Melissa J. Lucero, Nishant K. Rana, Gemlyn George, Saini Setua, Monika Dzieciatkowska, Kathryn Hassel, Christy S. Niemeyer, Kurt Stenmark, Eva Nozik, Angelo D'Alessandro, Paul W. Buehler, David C. Irwin   +17 more
wiley   +1 more source

Diving Deeper Into Mechanisms of Acrylamide‐Induced Toxicity: RNA Sequencing Reveals Transcriptomic Alteration and Retrotransposon Expression in Drosophila melanogaster

Environmental Toxicology, Volume 41, Issue 10, Page 1105-1118, October 2026.
ABSTRACT Given the inevitability of human and animal exposure to acrylamide, there is increasing concern regarding its potential health risks. While a number of molecular mechanisms have been proposed, the complexity of acrylamide toxicological pathways and interactions remains incompletely characterized.
Oluwabukola Mary Farodoye, Titilayomi Ayomide Otenaike, Daniela Moreira Mombach, Monica Medeiros Silva, Amos Olalekan Abolaji, Elgion Lucio Da Silva Loreto   +5 more
wiley   +1 more source

Microbially‐Induced Corrosion of Cobalt by Pseudomonas chlororaphis subspecies aureofaciens Is Driven by the Complex Interplay Between Abiotic and Biotic Processes That Control Cobalt Solubility

Environmental Microbiology, Volume 28, Issue 10, October 2026.
Cobalt undergoes microbially‐induced corrosion by the bacterium Pseudomonas chlororaphis subspecies aureofaciens. The reaction is initiated by oxygen or redox‐active metabolites that generate cobalt ions that interact with the cell. Corrosion is subsequently driven by unidentified cell‐derived ligands that keep cobalt in solution and inhibit the ...
Annika DeJager, Anna Kirkland, Aaron Hinz, David R. McMullin, Katherine Marczenko, Ichiko Sugiyama, Daniel S. Grégoire   +6 more
wiley   +1 more source

Functional Metagenomics Reveals Gut Microbial Biosynthetic Potential for Essential Nutrients in Juvenile Chum Salmon

Environmental Microbiology, Volume 28, Issue 10, October 2026.
At 35 days posthatching, the gut microbiome of juvenile chum salmon (Oncorhynchus keta) encodes complete biosynthetic pathways for essential amino acids (threonine, leucine, valine/isoleucine and lysine) and B‐vitamins (thiamine, riboflavin and biotin) that are absent or incomplete in the host genome. Bacterial taxa, including Bartonella, Acinetobacter
Subrata Kumar Ghosh, Mai A. Wassel, Marty Kwok‐Shing Wong, Susumu Hyodo, Koji Hamasaki   +4 more
wiley   +1 more source

Edible Rose and Roselle: A Critical Review of Nutritional Composition, Safety, and Regulatory Considerations for Product Development

Journal of Food Science, Volume 91, Issue 10, October 2026.
ABSTRACT The growing demand for sustainable and health‐promoting products has increased scientific and industrial interest in edible flowers as functional ingredients. Rose (Rosa spp.) and roselle (Hibiscus sabdariffa L.) have gained attention for their traditional use, diverse phytochemical composition, and emerging applications in functional foods ...
Temilola Dada, Susanne Neugart, Layla Engelhardt   +2 more
wiley   +1 more source

About heme biosynthesis.

Postepy higieny i medycyny doswiadczalnej, 2000
openaire   +1 more source