Results 51 to 60 of about 732,679 (273)

Distributions of particulate Heme b in the Atlantic and Southern Oceans - implications for electron transport in phytoplankton [PDF]

, 2013
Concentrations of heme b, the iron-containing component of b-type hemoproteins, ranged from  500). High chl a:heme b ratios resulted from relative decreases in heme b, suggesting proteins such as cytochrome b6f, the core complex of photosystem II, and ...
Nielsdottir, Maria C., Micha J. A. Rijkenberg, Achterberg, Eric P., David J. Honey, Rijkenberg, Micha J.A., Eric P. Achterberg, Maria C. Nielsdottir, Honey, David J., Gledhill, Martha, Martha Gledhill, Achterberg, E.P., Nielsdottir, M.C., Rijkenberg, M.J.A., Honey, D.J., Gledhill, M.   +14 more
core   +1 more source

Generation and characterization of human U-2 OS cell lines with the CRISPR/Cas9-edited protoporphyrinogen oxidase IX gene

Scientific Reports, 2022
In humans, disruptions in the heme biosynthetic pathway are associated with various types of porphyrias, including variegate porphyria that results from the decreased activity of protoporphyrinogen oxidase IX (PPO; E.C.1.3.3.4), the enzyme catalyzing the
Zora Novakova, Mirko Milosevic, Zsofia Kutil, Marketa Ondrakova, Barbora Havlinova, Petr Kasparek, Cristian Sandoval-Acuña, Zuzana Korandova, Jaroslav Truksa, Marek Vrbacky, Jakub Rohlena, Cyril Barinka   +11 more
doaj   +1 more source

Microbial Synthesis of Heme b: Biosynthetic Pathways, Current Strategies, Detection, and Future Prospects

Molecules, 2023
Heme b, which is characterized by a ferrous ion and a porphyrin macrocycle, acts as a prosthetic group for many enzymes and contributes to various physiological processes. Consequently, it has wide applications in medicine, food, chemical production, and
Qiuyu Yang, Juntao Zhao, Yangyang Zheng, Tao Chen, Zhiwen Wang   +4 more
doaj   +1 more source

Mutation in a chlorophyll-binding motif of Brassica ferrochelatase enhances both heme and chlorophyll biosynthesis.

Cell Reports, 2022
The heme branch of tetrapyrrole biosynthesis contributes to the regulation of chlorophyll levels. However, the mechanism underlying the balance between chlorophyll and heme synthesis remains elusive.
Meng-Yang Liu, Wei Ma, Xiangjie Su, Xiao-meng Zhang, Yin Lu, Shao-Wei Zhang, Jing-Hui Yan, Da-Ling Feng, Lisong Ma, Aoife Taylor, Yun-Jia Ge, Qi Cheng, Ke-Dong Xu, Yan-Hua Wang, Na Li, Ai-Xia Gu, Ju Zhang, Shuang-Xia Luo, Shu-Xin Xuan, Xue-Ping Chen, N. Scrutton, Cheng-Wei Li, Jian-Jun Zhao, Shu-Xing Shen   +23 more
semanticscholar   +1 more source

Update on heme biosynthesis, tissue-specific regulation, heme transport, relation to iron metabolism and cellular energy

Liver international (Print)
Heme is a primordial macrocycle upon which most aerobic life on Earth depends. It is essential to the survival and health of nearly all cells, functioning as a prosthetic group for oxygen‐carrying proteins and enzymes involved in oxidation/reduction and ...
A. Belot, Hervé Puy, I. Hamza, H. Bonkovsky   +3 more
semanticscholar   +1 more source

Heme A biosynthesis

Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2012
Respiration in plants, most animals and many aerobic microbes is dependent on heme A. This is a highly specialized type of heme found as prosthetic group in cytochrome a-containing respiratory oxidases. Heme A differs structurally from heme B (protoheme IX) by the presence of a hydroxyethylfarnesyl group instead of a vinyl side group at the C2 position
openaire   +2 more sources

Proteomic Analysis of Ferrochelatase Interactome in Erythroid and Non-Erythroid Cells

Life, 2023
Heme is an essential cofactor for multiple cellular processes in most organisms. In developing erythroid cells, the demand for heme synthesis is high, but is significantly lower in non-erythroid cells.
Chibuike David Obi, Harry A. Dailey, Yasaman Jami-Alahmadi, James A. Wohlschlegel, Amy E. Medlock   +4 more
doaj   +1 more source

Heme acquisition and tolerance in Gram-positive model bacteria: An orchestrated balance

Heliyon, 2023
As a nutrient, heme is important for various cellular processes of organism. Bacteria can obtain heme via heme biosynthesis or/and uptake of exogenous heme from the host. On the other side, absorption of excess heme is cytotoxic to bacteria.
Mengying Wang, Yuwei Wang, Mingshu Wang, Mafeng Liu, Anchun Cheng   +4 more
doaj   +1 more source

A Novel Pathway for the Biosynthesis of Heme in Archaea: Genome-Based Bioinformatic Predictions and Experimental Evidence [PDF]

, 2010
Heme is an essential prosthetic group for many proteins involved in fundamental biological processes in all three domains of life. In Eukaryota and Bacteria heme is formed via a conserved and well-studied biosynthetic pathway.
Rolfes, Sarah, Evelyne Raux-Deery, Gunhild Layer, Warren, Martin J., Sonja Storbeck, Raux-Deery, Evelyne, Dieter Jahn, Martin J. Warren, Layer, Gunhild, Jahn, Dieter, Storbeck, Sonja, Sarah Rolfes   +11 more
core   +1 more source

Development and validation of a method for porphyrins quantification using HPLC-UV in urine

Фармакокинетика и Фармакодинамика, 2022
Porphyrias are the group of orphan diseases, related to pathological disruptions of heme biosynthesis. These diseases are hard to diagnose timely and existing methods lack universality.
D. A. Kildyushkin, A. E. Petukhov, E. A. Litvin   +2 more
doaj   +1 more source