Results 141 to 150 of about 94,120 (279)
The Journal of Physiology, EarlyView.Abstract figure legend Graphical abstract of the proposed Ro5‐4864 mechanism of action via p62‐Keap1‐Nrf2 axis in heart failure. TSPO, the 18‐kDa mitochondrial translocator protein of the outer mitochondrial membrane, can directly interact with p62 (also known as SQSTM1), which is crucial for the degradation of damaged mitochondria by autophagy ...
Daphne A. Diloretto +7 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Sprint interval training (SIT) is a popular time‐efficient type of endurance training. Healthy young men performed nine SIT sessions (4–6 × 30 s all‐out cycling sprints) over 3 weeks while being supplemented with antioxidants (high doses of vitamins C and E) or placebo. Muscle biopsies taken before and after the first SIT session
Victoria L. Wyckelsma +12 more
wiley +1 more source
Diversity and conservation of interactions for binding heme in b-type heme proteins [PDF]
, 2007 Marles-Wright, Jon +3 more
core +1 more source
eFood, Volume 7, Issue 3, June 2026.Thinned apple polyphenols (TAP) extract reduced ferroptosis in acute and chronic lung injuries. TAP activated Nrf2 and modulated key biomarkers (MDA, NOX4, GPX4, FTH1), leading to decreased inflammation and fibrosis. These findings suggest TAP as a potential therapeutic approach for lung injury through ferroptosis regulation. ABSTRACT Acute and chronic
Rosalba Siracusa +8 more
wiley +1 more source
eFood, Volume 7, Issue 3, June 2026.Cubebene‐related sesquiterpenes, found across diverse biological sources, exhibit promising pharmacological activities, including anti‐inflammatory, neuroprotective, and anticancer effects. This review highlights their molecular diversity, ADME profiles, and predicted multitarget interactions, underscoring their therapeutic relevance and potential in ...
Khadija Boualam +4 more
wiley +1 more source
Postbiotic Supernatants From Psychobiotic Strains Modulate Antioxidant and Serotonergic Responses
eFood, Volume 7, Issue 3, June 2026.Cell‐free postbiotic supernatants obtained from psychobiotic strains exhibit strain‐dependent antioxidant and serotonergic effects. SCFA‐rich metabolites enhance antioxidant protection and modulate serotonin release in enterochromaffin cells, supporting their potential as functional ingredients for gut and brain health.
Cocean Ana‐Maria +6 more
wiley +1 more source
Various roles of heme oxygenase-1 in response of bone marrow macrophages to RANKL and in the early stage of osteoclastogenesis [PDF]
, 2018 Bukowska-Straková, Karolina +8 more
core +1 more source
Biomaterial Physical Cues as Gene Regulators for Cellular Agriculture
Advanced Genetics, Volume 7, Issue 2, June 2026.This review elucidates how biomaterial physical cues—ranging from matrix stiffness to remote electromagnetic fields—serve as extrinsic regulators of gene expression in cellular agriculture. By identifying central mechanotransduction pathways that bridge physical inputs to genetic remodeling, the authors propose the “Material Genome” concept: a ...
Jianuo Liu, Ye Liu
wiley +1 more source
GDNF modulates HO-1 expression in substantia nigra postnatal cell cultures [PDF]
, 1964 Heme oxygenase-1 (HO-1) has been strongly highlighted because of its induction in many cell types by toxic stimuli, including oxidative stress. The intense HO-1 immunostaining in the substantia nigra of Parkinson disease (PD) patients suggests its ...
Saavedra, Ana +3 more
core
Heme Oxygenase–1: A Cellular Hercules [PDF]
Hepatology, 2003 Brian S, Zuckerbraun, Timothy R, Billiar
openaire +2 more sources