Results 11 to 20 of about 137,322 (324)
Neural Regeneration Research, 2023 [INLINE:1] Previous studies have reported upregulation of heme oxygenase-1 in different central nervous system injury models. Heme oxygenase-1 plays a critical anti-inflammatory role and is essential for regulating cellular redox homeostasis.
Zhihua Wang +4 more
doaj +2 more sources
Impairment of neutrophil oxidative burst in children with sickle cell disease is associated with heme oxygenase-1 [PDF]
Haematologica, 2015 Sickle cell disease is a risk factor for invasive bacterial infections, and splenic dysfunction is believed to be the main underlying cause. We have previously shown that the liberation of heme in acute hemolysis can induce heme oxygenase-1 during ...
Ceri Evans +6 more
doaj +6 more sources
Clinical Significance of Heme Oxygenase 1 in Tumor Progression
Antioxidants, 2021 Heme oxygenase 1 (HO-1) plays a key role in cell adaptation to stressors through the antioxidant, antiapoptotic, and anti-inflammatory properties of its metabolic products.
Mariapaola Nitti +3 more
doaj +2 more sources
Heme Oxygenase-1 as a Modulator of Intestinal Inflammation Development and Progression [PDF]
Frontiers in Immunology, 2018 Heme Oxygenase 1 (HMOX1) is an enzyme that catalyzes the reaction that degrades the heme group contained in several important proteins, such as hemoglobin, myoglobin, and cytochrome p450.
Valentina P. Sebastián +9 more
semanticscholar +4 more sources
Heme oxygenase-1 in osteosarcoma
Journal of Cancer Research and Therapeutics, 2020 Aim of Study: The present study was planned to analyze serum heme oxygenase-1 levels in osteosarcoma patients. Materials and Methods: Twenty five histopathologically confirmed cases of osteosarcoma localized without metastasis of all the ages attending ...
S. Kharb, M. Halder, Z. Kundu
semanticscholar +3 more sources
How Heme Oxygenase-1 Prevents Heme-Induced Cell Death. [PDF]
PLoS ONE, 2015 Earlier observations indicate that free heme is selectively toxic to cells lacking heme oxygenase-1 (HO-1) but how this enzyme prevents heme toxicity remains unexplained.
Lilibeth Lanceta +3 more
doaj +4 more sources
Targeting the Nrf2-Heme Oxygenase-1 Axis after Intracerebral Hemorrhage. [PDF]
Current pharmaceutical design, 2017 BACKGROUND: Injury to cells adjacent to an intracerebral hemorrhage (ICH) is likely mediated at least in part by toxins released from the hematoma that initiate complex and interacting injury cascades.
J. Chen‐Roetling, R. Regan
semanticscholar +3 more sources
Heme oxygenase-1 deletion affects stress erythropoiesis. [PDF]
PLoS ONE, 2011 BACKGROUND:Homeostatic erythropoiesis leads to the formation of mature red blood cells under non-stress conditions, and the production of new erythrocytes occurs as the need arises.
Yu-An Cao +5 more
doaj +4 more sources
Immune-Related Functions of Heme Oxygenase-1
Antioxidants, 2023 Heme oxygenase (HO)-1 is a well-known cytoprotective enzyme due to its enzymatic action, which involves the catalysis of heme into anti-apoptotic and antioxidant molecules such as bilirubin, biliverdin and CO [...]
Elias A. Lianos, Maria G. Detsika
doaj +4 more sources
Heme catabolism and heme oxygenase-1-expressing myeloid cells in pathophysiology [PDF]
Frontiers in ImmunologyAlthough the pathological significance of myeloid cell heterogeneity is still poorly understood, new evidence indicates that distinct macrophage subsets are characterized by specific metabolic programs that influence disease onset and progression. Within
Francesca Maria Consonni +10 more
doaj +2 more sources