Heme oxygenase effect on mesenchymal stem cells action on experimental Alzheimer's disease [PDF]
, 2013 The objective is to evaluate the effect of heme oxygenase-1 (HO-1) enzyme inducer and inhibitor on Mesenchymal Stem Cells (MSCs) in Alzheimer disease. Materials and Methods: 70 female albino rats were divided equally into 7 groups as follows: group 1 ...
Abdel Aziz, M. T. +7 more
core
Endothelial HO-1 induction by model TG-rich lipoproteins is regulated through a NOX4-Nrf2 pathway [PDF]
, 2016 Circulating levels of chylomicron remnants (CMRs) increase postprandially and their composition directly reflects dietary lipid intake. These TG-rich lipoproteins likely contribute to the development of endothelial dysfunction, albeit via unknown ...
Botham, K M +3 more
core +1 more source
The Fate of Iron Released from Heme by Hemeoxygenase-1 [PDF]
, 2006 A strain of Escherichia coli was genetically modified to co-express human heme oxygenase-1 and ferritin. The E. coli were then grown with varying amounts of hemin to see if the iron released upon degradation of the hemin by heme oxygenase-1 is loaded ...
Gardner, Jonathan Mark
core +1 more source
Heme oxygenase is induced in nephrotoxic nephritis and hemin, a stimulator of heme oxygenase synthesis, ameliorates disease [PDF]
, 1998 Heme oxygenase is induced in nephrotoxic nephritis and hemin, a stimulator of heme oxygenase synthesis, ameliorates disease. Heme oxygenase (HO) catalyses degradation of heme to biliverdin, iron and carbon monoxide (CO).
Cattell, Victoria +3 more
core +1 more source
Regulation of T cell responses by Heme Oxygenase-1 [PDF]
, 2008 Tese de mestrado, Biologia (Biologia Molecular e Genética), 2008, Universidade de Lisboa, Faculdade de CiênciasMultiple sclerosis (MS) is a chronic inflammatory disease that affects the central nervous system (CNS).
Cortez, Eliane Cristina Monteiro
core
Subversion of the Heme Oxygenase-1 Antiviral Activity by Zika Virus
Viruses, 2018 Heme oxygenase-1 (HO-1), a rate-limiting enzyme involved in the degradation of heme, is induced in response to a wide range of stress conditions. HO-1 exerts antiviral activity against a broad range of viruses, including the Hepatitis C virus, the human ...
Chaker El Kalamouni +11 more
semanticscholar +1 more source
Nitric Oxide Mediates Biofilm Formation and Symbiosis in Silicibacter sp. Strain TrichCH4B. [PDF]
, 2015 UnlabelledNitric oxide (NO) plays an important signaling role in all domains of life. Many bacteria contain a heme-nitric oxide/oxygen binding (H-NOX) protein that selectively binds NO.
Marletta, Michael A +2 more
core +3 more sources
Heme Oxygenase 1 as a Therapeutic Target in Acute Kidney Injury.
American Journal of Kidney Diseases, 2017 A common clinical condition, acute kidney injury (AKI) significantly influences morbidity and mortality, particularly in critically ill patients. The pathophysiology of AKI is complex and involves multiple pathways, including inflammation, autophagy ...
Subhashini Bolisetty +2 more
semanticscholar +1 more source
An investigation into the feasibility of myoglobin-based single-electron transistors [PDF]
Nanotechnology 23, 395705 (2012), 2012 Myoglobin single-electron transistors were investigated using nanometer- gap platinum electrodes fabricated by electromigration at cryogenic temperatures. Apomyoglobin (myoglobin without heme group) was used as a reference. The results suggest single electron transport is mediated by resonant tunneling with the electronic and vibrational levels of the ...
arxiv +1 more source
A hem érfal komponensekre kifejtett közvetlen és közvetett patofiziológiai hatásai = Pathologic effects of heme on components of vessel wall via direct and indirect mechanisms [PDF]
, 2010 Kimutattuk, hogy az atheroma lipid magja prooxidáns környezetet teremt, ahol a vörösvértestek szétesnek, a hemoglobin ferri- és ferrylhemoglobinná oxidálódik, és a felszabaduló hem és vas lipidoxidációt indít el.
Balla, György +5 more
core