Results 121 to 130 of about 85,853 (215)

Designing Enzymatic Reactivity with an Expanded Palette

open access: yesChemBioChem, Volume 26, Issue 11, June 3, 2025.
Innovation in biocatalysis is rapidly increasingly the diversity of catalytic reactivity that can be mediated by enzymes, addressing a key bottleneck for their widespread adoption in industrial chemical synthesis. A key approach to this is building enzymes with unnatural catalytic components that provide an expanded palette with new possibilities for ...
Reuben B. Leveson‐Gower
wiley   +1 more source

Transforming a Historical Chemical Synthetic Route for Vanillin Starting from Renewable Eugenol to a Cell‐Free Bi‐Enzymatic Cascade

open access: yesChemSusChem, Volume 18, Issue 11, June 2, 2025.
An artificial enzymatic cascade to access natural vanillin from eugenol/clove oil was developed by revisiting the very first vanillin synthetic process from 19th century. The biosynthetic route consists of just two biocatalysts used as cell‐free preparation and molecular oxygen as oxidizing agent, outperforming also the natural microbial pathway which ...
Elisa Lanfranchi   +12 more
wiley   +1 more source

Multicargo Porous Cochlear Electrode Coating for Antifibrosis After Cochlear Implantation

open access: yesAdvanced Science, Volume 12, Issue 21, June 5, 2025.
This study presents a novel porous drug‐loading coating for cochlear electrodes, utilizing MA‐PDMS infused with GelMA hydrogel containing dexamethasone and MXene nanoparticles. The coating enhances biocompatibility, enables sustained drug release, reduces fibrosis, and preserves residual hearing post‐CI.
Lei Ren   +15 more
wiley   +1 more source

Anti‐Inflammatory and Antioxidant Activities of Polyphenols From Loquat (Eriobotrya japonica Lindl.) Leaf Hair in Lipopolysaccharide‐Induced In Vitro and In Vivo Models

open access: yeseFood, Volume 6, Issue 3, June 2025.
This study identifies polyphenols in loquat leaf hair with potent antioxidant and anti‐inflammatory activities, demonstrating their efficacy in mitigating LPS‐induced oxidative stress and inflammation In Vitro and In Vivo via modulation of the Jak2–Stat3 and Nrf2–Keap1 pathways.
Can Hu   +10 more
wiley   +1 more source

NADPH-Independent Fluorescent Probe for Live-Cell Imaging of Heme Oxygenase-1. [PDF]

open access: yesACS Sens
Li L   +7 more
europepmc   +1 more source

Influence of α‐Linolenic Acid on the Intestinal Barrier Integrity and Intestinal Antioxidant Status in Broilers

open access: yesFood Science &Nutrition, Volume 13, Issue 6, June 2025.
A summary of the findings and proposed mechanism of dietary α‐linolenic acid on the intestinal barrier integrity and intestinal antioxidant status in broilers. In this study, we discovered that the administration of ALA effectively enhances intestinal barrier function and improves intestinal antioxidant status in broilers. These effects were attributed
Ao Kang   +6 more
wiley   +1 more source

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