Results 121 to 130 of about 161,635 (252)

Catalytic Amyloids: Turning Fibrils Into Biocatalysts

Chemistry – A European Journal, Volume 32, Issue 10, 9 March 2026.
Amyloids, traditionally associated with diseases, have emerged as versatile catalytic scaffolds. From natural amyloid sequences to bioinspired and de novo designs, we highlight strategies to construct catalytic active sites and anchor enzymes onto fibrils, creating versatile nanomaterials with tunable activities. ABSTRACT Amyloids have been regarded as
Alessandra Esposito, Linda Leone, Flavia Nastri, Angela Lombardi   +3 more
wiley   +1 more source

Photophysical Properties of a Mn(I) Tricarbonyl PhotoCORM With 8‐Aminoquinoline Ligand: Insights From Theory

Journal of Computational Chemistry, Volume 47, Issue 6, March 5, 2026.
The computation of the photophysical properties of the Mn(I) fac‐[MnBr(CO)3(AQ)] photoCORM shows how different solvents can influence structural and light‐triggered behavior for CO molecules release, very likely occurring from triplet states with MC character.
Daniele Belletto, Domenico Pisano, Ahmed M. Mansour, Gloria Mazzone, Tamer Shoeib, Emilia Sicilia   +5 more
wiley   +1 more source

Dysfunctional TRIM31 of POMC Neurons Provokes Hypothalamic Injury and Peripheral Metabolic Disorder under Long‐Term Fine Particulate Matter Exposure

Advanced Science, Volume 13, Issue 14, 9 March 2026.
Particulate matter ≤2.5 µm (PM2.5) elevates risks of neurological and chronic metabolic diseases, but the underlying mechanisms linking PM2.5‐induced central nervous system (CNS) injury to metabolic dysfunction remain unclear. Hypothalamic pro‐opiomelanocortin‐expressing (POMC+) neurons regulate systemic metabolic homeostasis, and tripartite motif ...
Chenxu Ge, Jiamao Lin, Changsheng Yang, Chuanwang Miao, Fengxiang Li, Shuqiang Zhao, Lei Zou, Xuedong Teng, Lina Liu, Tingguang Li, Yan Sun, Qiang Li, Deshuai Lou, Linfeng Hu, Xi Liu, Gang Kuang, Jing Luo, Minxuan Xu, Minghui Chang, Jun Tan, Yanrong Ren, Bochu Wang   +21 more
wiley   +1 more source

Heme Oxygenase 1 as a Therapeutic Target in Acute Kidney Injury.

American Journal of Kidney Diseases, 2017
Subhashini Bolisetty, Abolfazl Zarjou, A. Agarwal   +2 more
semanticscholar   +1 more source

Gallium‐Doped MXene Nanozymes Protect Liver Through Multi‐Death Pathway Blockade and Hepatocyte Regeneration

Advanced Science, Volume 13, Issue 14, 9 March 2026.
This study develops gallium‐doped V2C MXene nanozymes (Ga‐V2C) to treat acetaminophen‐induced liver injury through multi‐death pathway blockade and hepatocyte regeneration. Unlike conventional single‐target therapies like N‐acetylcysteine, Ga‐V2C nanozymes enable oxidative stress suppression, apoptosis, and ferroptosis inhibition, and enhanced ...
Xiaopeng Cai, Jingwen Deng, Liqing Wang, Junjie Su, Dongyi Xian, Yilang Yan, Xinyu Yang, Chuanbin Wu, Tingting Peng, Yuan Ding, Guilan Quan, Weilin Wang, Min Zhou, Chao Lu   +13 more
wiley   +1 more source

Reappraising heme oxygenase-1 as a ferroptosis modulator in atherosclerosis: a mechanism-focused review. [PDF]

Front Immunol
Xu J, Chen C, Yuan HY, Zhang YY, Wang CR, Xi X, Pan H, Li DH, Lu Y.   +8 more
europepmc   +1 more source

CRISPLD2 Attenuates Intervertebral Disc Degeneration by Suppressing Oxidative Stress‐Induced Ferroptosis through the miR‐548I‐IL17A Axis

Advanced Science, Volume 13, Issue 16, 18 March 2026.
This study identifies CRISPLD2 as a key protector against IVDD. By regulating ferroptosis through the CRISPLD2–miR‐548I–IL17A axis, CRISPLD2 maintains NPCs homeostasis and reduces oxidative stress. Restoring CRISPLD2 expression effectively alleviates disc degeneration and highlights a promising therapeutic strategy for discogenic low back pain ...
Yangyang Shi, Fudong Li, Tianyi Zhao, Kaiqiang Sun, Danying Zhang, Chen Yan, Ximing Xu, Jingchuang Sun, Xulin Hu, Xin Yong, Jiangang Shi, Yuan Wang   +11 more
wiley   +1 more source

Control of renal central carbon metabolism by heme oxygenase-1. [PDF]

iScience
Guerra J, Jentho E, Schäuble S, Scicluna BP, Vivas W, Martínez-Alarcón D, Groth M, King E, Röstel F, Hirth G, Soares MP, Wiech T, Panagiotou G, Bauer M, Hoerr V, Weis S.   +15 more
europepmc   +1 more source

Modulation of Antiviral Immunity by Heme Oxygenase-1.

American Journal of Pathology, 2017
Janyra A. Espinoza, P. González, A. Kalergis   +2 more
semanticscholar   +1 more source

Two Contrasting Cases of Early Viral Clearance of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS‐CoV‐2) Treated With Shosaikotokakikyosekko

Traditional &Kampo Medicine, Volume 13, Issue 1, April 2026.
Hidehiro Watanabe, Itaru Nakamura, Yoshihide Yakazu, Akihito Ichiki, Tetsuo Oikawa   +4 more
wiley   +1 more source