Results 131 to 140 of about 85,853 (215)

Heme oxygenase 1 confers gilteritinib resistance in FLT3-ITD acute myeloid leukemia in a STAT6-dependent manner. [PDF]

Cancer Cell Int
Zhang T, Wei D, Zhan Y, Long Z, Lu T, Zhao P, Gao R, Kang Q, Zhang L, Liu M, Yang X, Wang J.   +11 more
europepmc   +1 more source

Role and Mechanisms of the mTOR Signalling Pathway in the Synthesis of Milk Components

Modern Agriculture, Volume 3, Issue 1, June 2025.
The regulatory network system of mTOR regulates lactose, milk fat, and milk protein. Milk is urgently needed for the strong development of the dairy industry to meet the growing demand and ensure that the nutritional needs of the world's population are met.
RongNuo Li, YiNing Zheng, HuiJun Geng, Lu Deng   +3 more
wiley   +1 more source

Heme oxygenase-1: potential therapeutic targets for periodontitis. [PDF]

PeerJ
Lv W, Hu S, Yang F, Lin D, Zou H, Zhang W, Yang Q, Li L, Chen X, Wu Y.   +9 more
europepmc   +1 more source

Oxidative Stress in Antigen Processing and Presentation

MedComm – Oncology, Volume 4, Issue 2, June 2025.
Reactive oxygen species (ROS) play a crucial role in antigen processing and presentation, essential for linking innate and adaptive immunity. While balanced ROS levels promote immune function, excess ROS can disrupt antigen recognition, resulting in immune dysfunction.
Qinxia Chang, Yaying Zhang, Xiaojun Liu, Peng Miao, Wenbing Pu, Shanshan Liu, Jing Zhang, Yuan Tian, Guobo Shen, Na Xie   +9 more
wiley   +1 more source

Heme oxygenase/carbon monoxide system and development of the heart. [PDF]

Med Gas Res
Mahan VL.
europepmc   +1 more source

An Overview of Heme Oxygenase

Experimental Biology and Medicine, 2003
openaire   +2 more sources

Burdock Fructooligosaccharide Protects Against Diabetic Nephropathy in Mice by Regulating Nrf2 Signaling

Pharmacology Research &Perspectives, Volume 13, Issue 3, June 2025.
In short, this study found that BFO could protect DN mice against renal injury induced by a high‐fat diet combined with STZ. Its protective effect may depend on the Nrf2/HO‐1 signaling pathway. ABSTRACT Diabetic nephropathy (DN) is a common complication of diabetes mellitus, with oxidative stress playing a critical role in its development.
Lei Zhu, Mengru Ding, Lina Liu, Pingchuan Yuan, Taili Shao, Chunyan Liu, Chuanhu Xi, Jun Han, Yuyan Zhou, Donglin Zhang, Guodong Wang   +10 more
wiley   +1 more source

Severity of Repetitive Mild Traumatic Brain Injury Depends on Microglial Heme Oxygenase-1 and Carbon Monoxide. [PDF]

Eur J Neurosci
Kaiser S, Fritsch A, Jakob L, Schallner N.   +3 more
europepmc   +1 more source

Colo‐Protective Effects of Pentoxifylline Alone or in Combination With Mesalamine in Colitis Through Sphingosine Kinase 1/Sphingosine 1 Phosphate, and Zonula Occuldin 1 Pathways: New Molecular Approach

Pharmacology Research &Perspectives, Volume 13, Issue 3, June 2025.
ABSTRACT Multiple signaling pathways have been implicated in the pathogenesis of ulcerative colitis (UC), including Sphingosine Kinase 1 (SPHK)/Sphingosine‐1‐Phosphate (S1P), AMP‐activated protein kinase (AMPK)/mammalian target of rapamycin (mTOR)/NLR family pyrin domain‐containing 3 (NLRP3), zonula occludens‐1 (ZO‐1), and signal transducer and ...
Fatemah A. Alherz, Mahmoud S. Abdallah, Esraa M. Mosalam, Mostafa M. Bahaa, Thanaa A. Elmasry, Mohamad A. El‐Gammal, Walaa A. Negm, AyaIbrahim Elberri, Nora Elshorbagi, Hend E. Abo Mansour, Amir O. Hamouda, Muhammed M. Salahuddin, Mohamed Yasser, Mamdouh Eldesoqui, Sarah Alrubia, Amsha S. Alsegiani, Eman El‐Khateeb, Mohamed Kh. ElMahdy, Eman Wahsh   +18 more
wiley   +1 more source

Heme catabolism and heme oxygenase-1-expressing myeloid cells in pathophysiology. [PDF]

Front Immunol
Consonni FM, Incerti M, Bertolotti M, Ballerini G, Garlatti V, Sica A.   +5 more
europepmc   +1 more source