Results 131 to 140 of about 133,631 (206)

Targeting Regulation of Macrophage to Treat Metabolic Disease: Role of Phytochemicals

Cell Proliferation, EarlyView.
One‐third of the world's population is affected by metabolic syndrome. Complicated pathogenesis and limited drugs cause the growing prevalence of metabolic syndrome. Macrophage‐mediated metaflammation is closely associated with the development of metabolic syndrome. The role of phytochemicals targeting macrophages in the treatment of metabolic syndrome
Zeting Ye, Yanlin Li, Xiaolin Yang, Chenglin Li, Rui Yu, Guangjuan Zheng, Zuqing Su   +6 more
wiley   +1 more source

Heme oxygenase/carbon monoxide system and development of the heart. [PDF]

Med Gas Res
Mahan VL.
europepmc   +1 more source

Translational Significance of Heme Oxygenase in Obesity and Metabolic Syndrome.

TIPS - Trends in Pharmacological Sciences, 2016
N. Abraham, Joshua M Junge, G. Drummond
semanticscholar   +1 more source

KYNA Ameliorates Hepatic Ischemia–Reperfusion Injury by Activating the Hippo Signalling Pathway via FTO‐Dependent m6A Demethylation of LATS1

Cell Proliferation, EarlyView.
Our study elucidates the cellular and molecular mechanisms underlying KYNA's protective effects against HIRI. It emphasises that KYNA modulates the methylation status of the Hippo signalling pathway through the activation of AHR, thereby mitigating damage by promoting LATS1 degradation and facilitating the nuclear translocation of YAP. ABSTRACT Hepatic
Wenjie Zheng, Xiaowen Wang, Haoqi Chen, Kaiming He, Xijing Yan, Yuan Zhang, Yang Yang, Peng Zhang, Wenfeng Zhu, Shuguang Zhu, Hua Li   +10 more
wiley   +1 more source

Severity of Repetitive Mild Traumatic Brain Injury Depends on Microglial Heme Oxygenase-1 and Carbon Monoxide. [PDF]

Eur J Neurosci
Kaiser S, Fritsch A, Jakob L, Schallner N.   +3 more
europepmc   +1 more source

Modulation of Antiviral Immunity by Heme Oxygenase-1.

American Journal of Pathology, 2017
Janyra A. Espinoza, P. González, A. Kalergis   +2 more
semanticscholar   +1 more source

Heme catabolism and heme oxygenase-1-expressing myeloid cells in pathophysiology. [PDF]

Front Immunol
Consonni FM, Incerti M, Bertolotti M, Ballerini G, Garlatti V, Sica A.   +5 more
europepmc   +1 more source

Malaria parasites require a divergent heme oxygenase for apicoplast gene expression and biogenesis. [PDF]

Elife
Blackwell AM, Jami-Alahmadi Y, Nasamu AS, Kudo S, Senoo A, Slam C, Tsumoto K, Wohlschlegel JA, Manuel Martinez Caaveiro J, Goldberg DE, Sigala PA.   +10 more
europepmc   +1 more source

Gastrodin plays a protective role in alleviating hepatic ischemia reperfusion injury by regulating heme oxygenase-1 expression. [PDF]

Braz J Med Biol Res
He SS, Huang HF, Shi SQ, Zhao JJ, Yuan B, Ji X, Zhang HB.   +6 more
europepmc   +1 more source

Achilles tenocytes from diabetic and non diabetic donors exposed to hyperglycemia respond differentially to inflammatory stimuli and stretch

Journal of Anatomy, EarlyView.
Scheme depicting the experimental set up of the study. Achilles tendons and tenocytes were isolated from heterozygous (fa/+, non diabetic: non DMT2) and homozygous (fa/fa, diabetic: DMT2) Zucker Diabetic Fatty (ZDF) rats. Tendon degeneration, collagen type 1 alpha 1 chain (COL1A1) and alpha smooth muscle actin (αSMA) expression was determined in rat ...
Nils Fleischmann, Sarah Hofmann, Clemens Gögele, Eva Frank, Christian Werner, Maria Kokozidou, Bernd Hoffmann, Jens Konrad, Gundula Schulze‐Tanzil   +8 more
wiley   +1 more source