Results 161 to 170 of about 146,694 (331)

Achilles tenocytes from diabetic and non diabetic donors exposed to hyperglycemia respond differentially to inflammatory stimuli and stretch

Journal of Anatomy, EarlyView.
Scheme depicting the experimental set up of the study. Achilles tendons and tenocytes were isolated from heterozygous (fa/+, non diabetic: non DMT2) and homozygous (fa/fa, diabetic: DMT2) Zucker Diabetic Fatty (ZDF) rats. Tendon degeneration, collagen type 1 alpha 1 chain (COL1A1) and alpha smooth muscle actin (αSMA) expression was determined in rat ...
Nils Fleischmann, Sarah Hofmann, Clemens Gögele, Eva Frank, Christian Werner, Maria Kokozidou, Bernd Hoffmann, Jens Konrad, Gundula Schulze‐Tanzil   +8 more
wiley   +1 more source

Induction of heme oxygenase in rat liver. Increase of the specific mRNA by treatment with various chemicals and immunological identity of the enzymes in various tissues as well as the induced enzymes.

, 1983
S. Ishizawa, Tadashi Yoshida, Goro Kikuchi   +2 more
openalex   +1 more source

Raised levels of exhaled carbon monoxide are associated with an increased expression of heme oxygenase-1 in airway macrophages in asthma: a new marker of oxidative stress [PDF]

, 1998
Ildikó Horváth, Louise Donnelly, András Kiss, Paolo Paredi, Sergei A. Kharitonov, Peter J. Barnes   +5 more
openalex   +1 more source

Genome‐Wide Analysis of DtxR and HrrA Regulons Reveals Novel Targets and a High Level of Interconnectivity Between Iron and Heme Regulatory Networks in Corynebacterium glutamicum

Molecular Microbiology, EarlyView.
Iron is essential for life, yet excessive levels can quickly lead to cellular damage via oxidative stress, underscoring the need for global regulators of iron and heme homeostasis. In this study, we present a genome‐wide analysis of the binding patterns of DtxR and HrrA in Corynebacterium glutamicum.
Aileen Krüger, Ulrike Weber, Julia Frunzke   +2 more
wiley   +1 more source

Mechanism of action of heme oxygenase. A study of heme degradation to bile pigment by 18O labeling.

, 1984
John C. Docherty, Brent Schacter, G D Firneisz, Stanley B. Brown   +3 more
openalex   +1 more source

A Review of the Mechanisms of Action of the Herbal Medicine, STW 5‐II, Underlying Its Efficacy in Disorders of Gut–Brain Interaction

Neurogastroenterology &Motility, EarlyView.
The pathophysiology of functional dyspepsia and irritable bowel syndrome includes altered motility, secretion, sensitivity to sensory signals, impaired epithelial barrier function, inflammation, and gut dysbiosis. The phytomedicine, STW 5‐II, represents a multi‐targeted approach, addressing these pathophysiologies.
Anita Annaházi, Rudolf Bauer, Thomas Efferth, Mohamed T. Khayyal, Michael Schemann, Gudrun Ulrich‐Merzenich, Christine Feinle‐Bisset   +6 more
wiley   +1 more source

Transcriptional control of the rat heme oxygenase gene by a nuclear protein that interacts with adenovirus 2 major late promoter

, 1989
Maria Notomi Sato, Yoshiyuki Fukushi, S. Ishizawa, Shoji Okinaga, Rolf Müller, Shigeki Shibahara   +5 more
openalex   +1 more source

Oxygen toxicity and iron accumulation in the lungs of mice lacking heme oxygenase-2. [PDF]

, 1998
Phyllis A. Dennery, Douglas R. Spitz, Gangyi Yang, Arthur Tatarov, C S Lee, Mychelle Shegog, Kenneth D. Poss   +6 more
openalex   +1 more source

Expression of a constitutively active nitrate reductase increases SARS‐CoV‐2 Spike protein production in Nicotiana benthamiana leaves that otherwise show traits of senescence

Plant Biotechnology Journal, EarlyView.
Summary The production of coronavirus disease 2019 vaccines can be achieved by transient expression of the Spike (S) protein of Severe Acute Respiratory Syndrome Coronavirus 2 in agroinfiltrated leaves of Nicotiana benthamiana, a process promoted by the co‐expression of viral silencing suppressor P19.
Louis‐Philippe Hamel, Marie‐Ève Paré, Francis Poirier‐Gravel, Rachel Tardif, Marc‐André Comeau, Pierre‐Olivier Lavoie, Andréane Langlois, Marie‐Claire Goulet, Marc‐André D'Aoust, Dominique Michaud   +9 more
wiley   +1 more source

Hemodynamic forces induce the expression of heme oxygenase in cultured vascular smooth muscle cells. [PDF]

, 1997
Carina Wagner, William Durante, Nicolaos Christodoulides, J. D. Hellums, AI Schafer   +4 more
openalex   +1 more source