Results 171 to 180 of about 64,501 (277)

Heme oxygenase-like dimetal oxidases and oxygenases. [PDF]

open access: yesBiochem Soc Trans
Skirboll SS, Ledinina AE, Makris TM.
europepmc   +1 more source

α7nAChR agonist GTS‐21 ameliorates sepsis‐induced acute kidney injury via MEF2/PGC‐1α/HO‐1 axis in mice

open access: yesClinical and Translational Medicine, Volume 16, Issue 7, July 2026.
This diagram illustrates opposing pathways regulating AKI (acute kidney injury). The left pathway shows LPS/TLR4 triggering mitochondrial damage (low MMP, Cyt C release, ROS) leading to apoptosis. The right pathway shows α7nAChR agonists activating MEF2 to upregulate PGC‐1α/HO‐1, promoting mitochondrial biogenesis and inhibiting injury, highlighting ...
Yu‐Jia Tang   +15 more
wiley   +1 more source

Redox mechanisms of the beneficial effects of heme oxygenase in hypertension

open access: yes, 2014
Heme oxygenases, namely heme oxygenase-1 and heme oxygenase-2, have important biological functions in vascular homeostasis. Heme oxygenase and its catabolic products, including bilirubin and carbon monoxide, have been implicated in blood pressure ...
Dusting, GJ (15629489)   +3 more
core  

Heme oxygenase-1 activation in mononuclear phagocytes in acute Kawasaki disease. [PDF]

open access: yesFront Pediatr
Zeng J   +8 more
europepmc   +1 more source

Therapeutic Potential of Berberis vulgaris in Modulating Metabolic Syndrome Biomarkers: Mechanistic Insights and Functional Food Implications

open access: yesFood Frontiers, Volume 7, Issue 4, July 2026.
ABSTRACT Barberry (Berberis vulgaris) has emerged as a promising functional food candidate for the management of metabolic syndrome due to its diverse bioactive constituents, particularly berberine. This review synthesizes current experimental and clinical evidence regarding its effects on glycemic control, lipid metabolism, blood pressure regulation ...
Fakhar Shahid   +5 more
wiley   +1 more source

Apple Pomace Pectin for Gastroprotective Nutraceutical Delivery: Structure–Function Relationships and Nano/Microencapsulation Strategies for Gastric Ulcer Management

open access: yesFood Frontiers, Volume 7, Issue 4, July 2026.
Apple pomace pectin is explored as a sustainable and multifunctional biomaterial for gastric ulcer management. Its unique structural features confer mucoadhesive, anti‐inflammatory, antioxidant, and anti‐Helicobacter pylori activities while enabling nano/microencapsulation of therapeutic agents.
Akash Dhiman   +6 more
wiley   +1 more source

Advances in the Neurotoxic Mechanisms of Acrylamide and Multitarget Intervention Strategies of Natural Products

open access: yesFood Frontiers, Volume 7, Issue 4, July 2026.
This review summarizes recent advances in acrylamide neurotoxicity mechanisms and highlights the multitarget neuroprotective effects of diverse natural products while also addressing current challenges and future translational research directions.
Wen Du   +7 more
wiley   +1 more source

Research on the Mechanism of Natural Products Acting on Chronic Obstructive Pulmonary Disease

open access: yesFood Science &Nutrition, Volume 14, Issue 7, July 2026.
This figure illustrates that approximately 80 natural compounds exert therapeutic effects against chronic obstructive pulmonary disease by targeting pathological mechanisms such as airway inflammation, oxidative stress, airway remodeling, mucus hypersecretion, emphysema, protease–antiprotease imbalance, apoptosis, and autophagy.
Shuna Wei, Xiaoju Liu
wiley   +1 more source

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