Results 161 to 170 of about 64,501 (277)

Born early, age fast: Consequences of premature birth on chronic disease and accelerated ageing

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend ELGANs are exposed to several postnatal pro‐oxidant stressors, including ambient and supplemental oxygen, mechanical ventilation, infections, hyperalimentation, excessive glucocorticoids and intermittent hypoxia. Since endogenous antioxidant defences are underdeveloped, this imbalance promotes oxidative stress and inflammation ...
Estelle B. Gauda   +5 more
wiley   +1 more source

Resveratrol: Advance on the Most Recent Research From 2021 to 2025

open access: yesPhytochemicals in Food and Medicine, Volume 1, Issue 3, September 2026.
This review summarizes recent progress in resveratrol research (2021–2025), highlighting its natural sources, bioactivities, clinical evidence, and safety profiles. Resveratrol exerts multi‐target effects through the regulation of oxidative stress, inflammation, mitochondrial function, and gut microbiota.
Quanyong Wu   +4 more
wiley   +1 more source

The heme-heme oxygenase system in inflammation [PDF]

open access: yes, 2002
Contains fulltext : 146899.pdf (Publisher’s version ) (Open Access)
openaire  

Moutan Cortex Extract Mediates Diabetic Retinopathy by Blocking the ROS‑Triggered HIF‐1α/VEGF Axis in Retinal Pigment Epithelial Cells

open access: yeseFood, Volume 7, Issue 4, August 2026.
Schematic diagram of the mechanism by which Moutan Cortex extract (MCE) ameliorates DR. MCE alleviates retinal structural damage and reduces neovascular lesions by downregulating the ROS/HIF‐1α/VEGF signaling axis. ABSTRACT Moutan Cortex is a functional food ingredient with multiple health benefits, but its effects on diabetic retinopathy (DR) remain ...
Mei‐rong Li   +13 more
wiley   +1 more source

Natural History of Chronic Kidney Disease in Sickle Cell Disease

open access: yesAmerican Journal of Hematology, Volume 101, Issue 7, Page 1456-1477, July 2026.
ABSTRACT Kidney complications, referred to as nephropathy, develop early in sickle cell disease (SCD). In addition to its known morbidity, abundant data show that chronic kidney disease (CKD) is associated with an increased mortality risk in SCD. Increasing evidence suggests that the natural history of SCD nephropathy is progressive. Initial glomerular
Kenneth I. Ataga
wiley   +1 more source

A Novel Plasma Heme Assay Reveals Disease Severity in Beta‐Thalassemia and Sickle Cell Anemia

open access: yesAmerican Journal of Hematology, Volume 101, Issue 7, Page 1706-1716, July 2026.
ABSTRACT Anemia results from imbalanced hemoglobin or red blood cell production and clearance. Hemolytic anemia, caused by premature red blood cell removal, can be intravascular (in blood) or extravascular (erythrophagocytosis). Hemolysis is common in Sickle Cell Disease (SCD) and Beta‐Thalassemia anemia (β‐thalassemia), the most prevalent inherited ...
Laurent Kiger   +14 more
wiley   +1 more source

Impairment of Oxidative Stress-Induced Heme Oxygenase-1 Expression by the Defect of Parkinson-Related Gene of Pink1

open access: yes, 2012
P>Parkinsons disease PD is one of the most common neurodegenerative diseases. Mutation in the phosphatase and tensin homolog PTEN-induced putative kinase 1 PINK1 gene causes an autosomal recessive form of PD.
錢韋伶;李政叡;洪詩雅;康凱翔;李銘仁;符文美   +1 more
core  

Heme oxygenase-1 and malaria pathogenesis. [PDF]

open access: yesFront Immunol
Wakai T, Chinedu S, Afolabi I.
europepmc   +1 more source

Identification of PRKCB, NLRC4, and TNFSF10 as Key Regulators of the Lipid Metabolism‐Autophagy Network in Atherosclerosis

open access: yesCell Biochemistry and Function, Volume 44, Issue 7, July 2026.
ABSTRACT Background The occurrence and development of atherosclerosis (AS) are closely related to disorders of lipid metabolism and dysfunction of autophagy. However, the key regulatory genes and immune microenvironment characteristics require further exploration. Methods This study integrated the bulk transcriptome and single‐cell RNA sequencing data,
Min Li   +3 more
wiley   +1 more source

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