Results 211 to 220 of about 188,137 (274)

Differential Effects of Wild Blueberry (Poly)Phenol Metabolites in Modulating Lipid Metabolism and Oxidative Stress in 3T3‐L1 Adipocytes

Molecular Nutrition &Food Research, Volume 69, Issue 15, August 2025.
Metabolites derived from wild blueberry (poly)phenols, such as syringic (SA), vanillic (VA), and isoferulic acids (IA), can modulate lipid metabolism and oxidative stress markers in mature 3T3‐L1 adipocytes treated with free fatty acids (FFAs; oleic/palmitic acid, 750 µM, 2:1 ratio).
Samuele Venturi, Marco Rendine, Mirko Marino, Dorothy Klimis‐Zacas, Patrizia Riso, Cristian Del Bo'   +5 more
wiley   +1 more source

Heme Oxygenase-2 Is Neuroprotective in Cerebral Ischemia

, 1999
Sylvain Doré, Kenji Sampei, Shozo Goto, Nabil J. Alkayed, Daniel Guastella, Seth Blackshaw, Michela Gallagher, Richard J. Traystman, Patricia D. Hurn, Raymond C. Koehler, Solomon H. Snyder   +10 more
openalex   +1 more source

Heme Oxygenase‐1 and NADPH Cytochrome P450 Reductase Expression in Experimental Allergic Encephalomyelitis [PDF]

, 2000
Mitchell R. Emerson, Steven M. LeVine
openalex   +1 more source

Gastrodin plays a protective role in alleviating hepatic ischemia reperfusion injury by regulating heme oxygenase-1 expression. [PDF]

Braz J Med Biol Res
He SS, Huang HF, Shi SQ, Zhao JJ, Yuan B, Ji X, Zhang HB.   +6 more
europepmc   +1 more source

A Common Mutation in the Homeostatic Iron Regulatory Gene Alters Astrocyte Migration and Redox Profile

FASEB BioAdvances, Volume 7, Issue 8, August 2025.
H67D HFE astrocytes exhibited alterations in migration and redox profile at baseline that persisted after a physical challenge. These characteristics of H67D HFE astrocytes might be driven by an adaptive hormetic response to minor iron dysregulation. ABSTRACT Astrocytes play a vital role in maintaining homeostasis and function in the central nervous ...
Makenzie Nolt, Elizabeth Neely, Sina Kheirabadi, Arian Jaberi, Amir Sheikhi, James Connor   +5 more
wiley   +1 more source

Replacement of the Distal Glycine 139 Transforms Human Heme Oxygenase-1 into a Peroxidase [PDF]

, 2000
Yi Liu, Luke Koenigs Lightning, Hong-wei Huang, Pierre Moënne‐Loccoz, David J. Schuller, T.L. Poulos, Thomas M. Loehr, Paul R. Ortiz de Montellano   +7 more
openalex   +1 more source

Navigating heme pathways: the breach of heme oxygenase and hemin in breast cancer. [PDF]

Mol Cell Biochem
Consoli V, Sorrenti V, Gulisano M, Spampinato M, Vanella L.   +4 more
europepmc   +1 more source

Lipocalin‐2 Restores Soluble Guanylyl Cyclase‐Dependent Dilation of the Afferent Arteriole After Renal Transplantation or Ex Vivo Hypoxia/Reoxygenation in Mice

Acta Physiologica, Volume 241, Issue 8, August 2025.
ABSTRACT Aim Dilatory microvascular function is impaired in ischemia/reperfusion injury in the kidney. Nitric oxide independent activators of soluble guanylyl cyclase (sGC) provide renal protection by dilating microvessels and preserving perfusion, but their efficacy declines after severe hypoxia.
Liang Zhao, Minze Xu, Anna Maria Pfefferkorn, Cem Erdogan, Hubert Schwelberger, Pinchao Wang, Pratik Hemant Khedkar, Marc Eigen, Falk‐Bach Lichtenberger, Rusan Catar, En Yin Lai, Felix Aigner, Pontus B. Persson, Igor Maximilian Sauer, Andreas Patzak, Muhammad Imtiaz Ashraf   +15 more
wiley   +1 more source

Correction: Atorvastatin inhibits Lipopolysaccharide (LPS)-induced vascular inflammation to protect endothelium by inducing Heme Oxygenase-1 (HO-1) expression. [PDF]

PLoS One
Luo J, Zhu Q, Huang K, Wen X, Peng Y, Wei G, Chen G.   +6 more
europepmc   +1 more source

Artemisinins in autoimmune diseases: effects and mechanisms in systemic lupus erythematosus and rheumatoid arthritis

British Journal of Pharmacology, Volume 182, Issue 15, Page 3411-3427, August 2025.
Abstract Autoimmune diseases such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) result from immune self‐tolerance loss, causing tissue damage. Standard treatments targeting late‐stage inflammation often have serious side effects. Artemisinin, known for its antimalarial properties, shows potential immunomodulatory effects.
Fanchao Zhou, Guoming Li, Ruixiang Tan, Guodong Wu, Changsheng Deng   +4 more
wiley   +1 more source