Results 241 to 250 of about 146,694 (331)

Catalase‐Encapsulated Nanoparticles via Surface Radical Polymerization for Periodontitis Therapy

Macromolecular Materials and Engineering, Volume 310, Issue 6, June 2025.
This study introduces catalase‐encapsulated nanoparticles (CAT NPs) designed to target the Nrf‐2/HO‐1 pathway for the treatment of periodontitis. CAT NPs demonstrate potent antioxidative and anti‐inflammatory properties, significantly reducing reactive oxygen species (ROS) and cytokine levels.
Tongtong Yan, Xiang Li, Shiqun Sun, Yuchao Luo, Haotian Shi, Nan Yang, Xue Ren, Wenjing Tian, Zhihui Liu, Bin Xu   +9 more
wiley   +1 more source

Inhibition of 11β-hydroxysteroid dehydrogenase 1 alleviates pulmonary fibrosis through inhibition of endothelial-to-mesenchymal transition and M2 macrophage polarization by upregulating heme oxygenase-1. [PDF]

Cell Death Dis
Lee SY, Kim JH, Song Y, Kim S, Kang HJ, Kim J, Lee YJ, Seo HR.   +7 more
europepmc   +1 more source

Structural basis for the electron transfer from an open form of NADPH-cytochrome P450 oxidoreductase to heme oxygenase

Proceedings of the National Academy of Sciences of the United States of America, 2014
M. Sugishima, Hideaki Sato, Y. Higashimoto, J. Harada, K. Wada, K. Fukuyama, M. Noguchi   +6 more
semanticscholar   +1 more source

The Nasal–Brain Drug Delivery Route: Mechanisms and Applications to Central Nervous System Diseases

MedComm, Volume 6, Issue 6, June 2025.
Τhe BBB restricts CNS drug delivery. NBDD bypasses the BBB via olfactory/trigeminal routes, enabling CNS delivery of therapeutic (small molecules, biologics, nucleic acids) for neurodegenerative/psychiatric disorders and brain tumors using advanced NBDD delivery systems (e.g nanocarriers) to enhance targeting and bioavailability.
Yi Qiu, Shiyuan Huang, Li Peng, Li Yang, Guosong Zhang, Tao Liu, Fang Yan, Xi Peng   +7 more
wiley   +1 more source

Heme oxygenase 1‑overexpressing bone marrow mesenchymal stem cell‑derived exosomes suppress interleukin‑1 beta‑induced apoptosis and aging of nucleus pulposus cells. [PDF]

Mol Med Rep
Zhang H, Zhang D, Wang H, Liu Y, Ding W, Fan G, Meng X.   +6 more
europepmc   +1 more source

Resveratrol: Molecular Mechanisms, Health Benefits, and Potential Adverse Effects

MedComm, Volume 6, Issue 6, June 2025.
As a polyphenol substance with important potential, resveratrol has important potential in degenerative diseases, cardiovascular diseases, cancer, neurological diseases, etc. However, it is still necessary to pay attention to its bioavailability and potential adverse effects.
Zhuo‐qun Ren, Sheng‐yuan Zheng, Zhengcheng Sun, Yan Luo, Yu‐tong Wang, Ping Yi, Yu‐sheng Li, Cheng Huang, Wen‐feng Xiao   +8 more
wiley   +1 more source

Heme Oxygenase-1 and Prostate Cancer: Function, Regulation, and Implication in Cancer Therapy. [PDF]

Int J Mol Sci
Salloom RJ, Ahmad IM, Sahtout DZ, Baine MJ, Abdalla MY.   +4 more
europepmc   +1 more source

INDUCTION OF HEME OXYGENASE AND NITRIC OXIDE SYNTHASE IN AN EXPERIMENTAL TUMOR IN RAT AND ITS IMPLICATION FOR TUMOR GROWTH

, 1997
Koichi Doi, Takaaki Akaike, Shin‐ichiro Fujii, Norisato Ikebe, Toru Beppu, Minetaro Ogawa, Shigeki Shibahara, Hiroshi Maeda   +7 more
openalex   +1 more source

Heme oxygenase-1 and acute kidney injury

Current opinion in nephrology and hypertension, 2014
K. Nath
semanticscholar   +1 more source

Role and Mechanisms of the mTOR Signalling Pathway in the Synthesis of Milk Components

Modern Agriculture, Volume 3, Issue 1, June 2025.
The regulatory network system of mTOR regulates lactose, milk fat, and milk protein. Milk is urgently needed for the strong development of the dairy industry to meet the growing demand and ensure that the nutritional needs of the world's population are met.
RongNuo Li, YiNing Zheng, HuiJun Geng, Lu Deng   +3 more
wiley   +1 more source