Results 21 to 30 of about 3,392 (222)
Mechanisms of Neuronal Damage in Acute Hepatic Porphyrias
Porphyrias are a group of congenital and acquired diseases caused by an enzymatic impairment in the biosynthesis of heme. Depending on the specific enzyme involved, different types of porphyrias (i.e., chronic vs. acute, cutaneous vs.
Andrea Ricci +3 more
doaj +1 more source
Femtosecond imaging of giant-hemeprotein with XFEL pulses
Published by Biophysical Soc., Bethesda, Md.
Lourdu Xavier, Paulraj +14 more
openaire +2 more sources
Optimization of Hnox Protein Production in Escherichia Coli
Hemeproteinscarry a variety of different functions in organisms ranging from steroidbiosynthesis to respiration, signaling to drug metabolism. In industry,hemeproteins are used for production of drugs such as: pravastatin for loweringcholesterol ...
Nur Başak Sürmeli
doaj +1 more source
Hypoxic Regulation of the Large-Conductance, Calcium and Voltage-Activated Potassium Channel, BK
Hypoxia is a condition characterized by a reduction of cellular oxygen levels derived from alterations in oxygen balance. Hypoxic events trigger changes in cell-signaling cascades, oxidative stress, activation of pro-inflammatory molecules, and growth ...
Sara V. Ochoa +9 more
doaj +1 more source
Hydrogen Sulfide and Hemeproteins: Knowledge and Mysteries [PDF]
Historically, hydrogen sulfide (H(2)S) has been regarded as a poisonous gas, with a wide spectrum of toxic effects. However, like ·NO and CO, H(2)S is now referred to as a signaling gas involved in numerous physiological processes. The list of reports highlighting the physiological effects of H(2)S is rapidly expanding and several drug candidates are ...
Ruth, Pietri +2 more
openaire +2 more sources
Abstract De novo purine biosynthesis is required for the incorporation of fixed nitrogen in ureide exporting nodules, as formed on soybean [Glycine max (L.) Merr.] roots. However, in many cases, the enzymes involved in this pathway have been deduced strictly from genome annotations with little direct genetic evidence, such as mutant studies, to confirm
Cuong X. Nguyen +5 more
wiley +1 more source
New insights into the role of heme oxygenase-1 in acute kidney injury
Acute kidney injury (AKI) is attended by injury-related biomarkers appearing in the urine and serum, decreased urine output, and impaired glomerular filtration rate.
Meryl Nath, Anupam Agarwal
doaj +1 more source
Encapsulation of sugar beet phytoglobin BvPgb 1.2 and myoglobin in a lipid sponge phase system
Globins are usually associated with oxygen carriage in vertebrates. However, plants also contain similar heme-containing proteins, called phytoglobins (Pgbs).
Jennifer Gilbert +7 more
doaj +1 more source
Label-free photoacoustic microscopy of cytochromes [PDF]
Photoacoustic microscopy (PAM) has achieved submicron lateral resolution in showing subcellular structures; however, relatively few endogenous subcellular contrasts have so far been imaged. Given that the hemeprotein, mostly cytochromes in general cells,
Wang, Lihong V. +4 more
core +1 more source
The effects of nitroxyl (HNO) on soluble guanylate cyclase activity: interactions at ferrous heme and cysteine thiols [PDF]
It has been previously proposed that nitric oxide (NO) is the only biologically relevant nitrogen oxide capable of activating the enzyme soluble guanylate cyclase (sGC). However, recent reports implicate HNO as another possible activator of sGC.
Adrian J. Hobbs +85 more
core +2 more sources

