Results 41 to 50 of about 3,386 (219)
Characterization of a globin-coupled oxygen sensor with a gene-regulating function [PDF]
, 2007 Globin-coupled sensors (GCSs) are multiple-domain transducers, consisting of a regulatory globin-like heme-binding domain and a linked transducer domain(s). GCSs have been described in both Archaea and bacteria. They are generally assumed to bind O2 (and
Alam, M +13 more
core +1 more source
Mechanism of Sulfide Binding by Ferric Hemeproteins
Inorganic Chemistry, 2018 The reaction of hydrogen sulfide (H2S) with hemeproteins is a key physiological reaction; still, its mechanism and implications are not completely understood. In this work, we propose a combination of experimental and theoretical tools to shed light on the reaction in model system microperoxidase 11 (MP11-FeIII) and myoglobin (Mb-FeIII), from the ...
Fernando M. Boubeta +5 more
openaire +3 more sources
Iron Metabolism: From Health to Disease [PDF]
, 2014 Background Iron is vital for almost all living organisms by participating in a wide range of metabolic processes. However, iron concentration in body tissues must be tightly regulated since excessive iron may lead to microbial infections or cause tissue
Fernandes, Rúben +2 more
core +1 more source
Journal of Lipid Research, 2018 The initial studies of the metabolism of arachidonic acid (AA) by the cytochrome P450 (P450) hemeproteins sought to: a) elucidate the roles for these enzymes in the metabolism of endogenous pools of the FA, b) identify the P450 isoforms involved in AA ...
Jorge H. Capdevila, John R. Falck
doaj +1 more source
Recent advances in column coatings for capillary electrophoresis of proteins [PDF]
, 2017 Capillary coatings effectively improve the separation performance of proteins in capillary electrophoresis, mainly by reducing protein adsorption onto the inner capillary wall and by regulating the electroosmotic flow (EOF) to accommodate the separation ...
Guttman, András, Hajba, László
core +1 more source
Fast ferrous heme-NO oxidation in nitric oxide synthases. [PDF]
, 2009 International audienceDuring catalysis, the heme in nitric oxide synthase (NOS) binds NO before releasing it to the environment. Oxidation of the NOS ferrous heme-NO complex by O2 is key for catalytic cycling, but the mechanism is unclear.
Santolini, J. +2 more
core +3 more sources
Heme on innate immunity and inflammation
Frontiers in Pharmacology, 2014 Heme is an essential molecule expressed ubiquitously all through our tissues. Heme plays major functions in cellular physiology and metabolism as the prostetic group of diverse proteins.
Fabianno Ferreira Dutra +1 more
doaj +1 more source
Characterisation of Bone Beneficial Components from Australian Wallaby Bone. [PDF]
, 2016 Background: Osteoporosis is a condition in which the bones become brittle, increasing the risk of fractures. Complementary medicines have traditionally used animal bones for managing bone disorders, such as osteoporosis.
Bishop, DP +9 more
core +2 more sources
Oxidation of Native and Modified Hemoglobin and Myoglobin by Sodium Nitrate. Effect of Inositol Hexaphosphate [PDF]
, 1981 Native and modified hemoglobin, myoglobin and a and phemoglobin subunits were oxidized by sodium nitrite at pH 6. The experiments were carried out under oxy and deoxy conditions with and without inositol hexaphosphate (IHP).
Mansouri, Ali
core +2 more sources
Density functional theory in transition-metal chemistry: a self-consistent Hubbard U approach
, 2006 Transition-metal centers are the active sites for many biological and inorganic chemical reactions. Notwithstanding this central importance, density-functional theory calculations based on generalized-gradient approximations often fail to describe ...
C. Rovira +5 more
core +1 more source