Results 121 to 130 of about 43,983 (296)

Crystal structural analysis of human serum albumin complexed with hemin and fatty acid [PDF]

open access: yes, 2003
BACKGROUND: Human serum albumin (HSA) is an abundant plasma protein that binds a wide variety of hydrophobic ligands including fatty acids, bilirubin, thyroxine and hemin.
Eishun Tsuchida   +5 more
core   +3 more sources

Towards an ab initio theory for metal L-edge soft X-ray spectroscopy of molecular aggregates [PDF]

open access: yesarXiv, 2016
The Frenkel exciton model was adapted to describe X-ray absorption and resonant inelastic scattering spectra of polynuclear transition metal complexes by means of restricted active space self-consistent field method. The proposed approach allows to substantially decrease the requirements to computational resources if compared to a full supermolecular ...
arxiv  

Rapid Amplification and Detection of Single‐Stranded Nucleic Acids for Point‐of‐Care Diagnosis

open access: yesSmall Methods, EarlyView.
A rapid, point‐of‐care nucleic acid test can greatly benefit healthcare system by providing timely diagnosis for effective treatment and patient management, as well as supporting diseases surveillance for emerging pandemic diseases. Recent advancements in nucleic acids technology have led to rapid assays for single‐stranded nucleic acids that can be ...
Jinglin Fu   +6 more
wiley   +1 more source

Receptor sites involved in posttranslational transport of apocytochrome c into mitochondria [PDF]

open access: yes, 1983
Assembly of cytochrome c involves a series of steps: synthesis of apocytochrome c on free ribosomes, specific binding of apocytochrome c to the mitochondrial surface, transfer across the outer membrane, covalent addition of protoheme, refolding of the ...
Hennig, Bernd   +2 more
core  

Gut microbiota metabolism of branched‐chain amino acids and their metabolites can improve the physiological function of aging mice

open access: yesAging Cell, Volume 24, Issue 4, April 2025.
Parabacteroides merdae in gut microbiota metabolizes branched‐chain amino acids into isovalerate, 2‐methylbutyrate, and isobutyrate, with key gene porA being less abundant in unhealthy elderly. Parabacteroides merdae and its three BSCFAs improve physiological functions in aging mice, with preliminary mechanism exploration through microbiome ...
Hongchao Wang   +5 more
wiley   +1 more source

High‐throughput screen identifies MAS9 as a novel inhibitor of the C‐type lectin receptor‐2 (CLEC‐2)–podoplanin interaction

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose The C‐type lectin‐like receptor‐2 (CLEC‐2) is a platelet receptor for the endogenous ligand podoplanin. This interaction contributes to several (patho)physiological processes, such as lymphangiogenesis, preservation of blood and lymphatic vessel integrity organ development, and tumour metastasis.
Marcin A. Sowa   +8 more
wiley   +1 more source

Effect of Hemin on Brain Alterations and Neuroglobin Expression in Water Immersion Restraint Stressed Rats

open access: yesScientifica, 2016
In the brain, the heme oxygenase (HO) system has been reported to be very active and its modulation seems to play a crucial role in the pathophysiology of neurodegenerative disorders.
Merhan Ragy, Fatma Ali, Maggie M. Ramzy
doaj   +1 more source

‘Eat, Sleep, School, Repeat’: The Influence of the Dutch Asylum System on the Capabilities and Aspirations of Unaccompanied Asylum‐Seeking Adolescents During Their Transition to Adulthood

open access: yesChildren &Society, EarlyView.
ABSTRACT This study examines the transition to adulthood of unaccompanied asylum‐seeking adolescents in the context of the Dutch asylum system. We thereby focus on adolescents' capabilities and their perceptions of the enabling or hampering role of the system, the laws and policies which constitute it, and the ways in which these are implemented and ...
K. Winkens   +3 more
wiley   +1 more source

Characterization of a Putative Hemolysin Expressed by Sneathia amnii, a Preterm Birth-associated Pathogen [PDF]

open access: yes, 2017
The gram-negative bacteria Sneathia amnii is a poorly-characterized commensal of the female urogenital tract frequently associated with adverse clinical outcomes such as bacterial vaginosis (BV), amnionitis, and preterm labor.
Carrasco, Lizette, Jefferson, Kimberly
core   +1 more source

RIP1 and RIP3 mediate hemin-induced cell death in HT22 hippocampal neuronal cells

open access: yesNeuropsychiatric Disease and Treatment, 2018
Xingfen Su,1 Handong Wang,2 Yuanxiang Lin,1 Fuxiang Chen1 1Department of Neurosurgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, Fujian, People’s Republic of China; 2Department of Neurosurgery, Jinling Hospital ...
Su X, Wang H, Lin Y, Chen F
doaj  

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