Results 31 to 40 of about 43,983 (296)

Biological Oxidations and Nitrations Promoted by the Hemin–Aβ₁₆ Complex

Antioxidants, 2023
Both β-amyloid (Aβ) peptides and oxidative stress conditions play key roles in Alzheimer’s disease. Hemin contributes to the development of the disease as it possesses redox properties and its level increases in pathological conditions or traumatic brain
Silvia De Caro, Giulia De Soricellis, Simone Dell’Acqua, Enrico Monzani, Stefania Nicolis   +4 more
doaj   +1 more source

Automatic Colon Polyp Detection using Region based Deep CNN and Post Learning Approaches [PDF]

IEEE Access 6 (2018): 40950-40962, 2019
Automatic detection of colonic polyps is still an unsolved problem due to the large variation of polyps in terms of shape, texture, size, and color, and the existence of various polyp-like mimics during colonoscopy. In this study, we apply a recent region based convolutional neural network (CNN) approach for the automatic detection of polyps in images ...
arxiv   +1 more source

Dysbiosis by neutralizing commensal mediated inhibition of pathobionts [PDF]

, 2016
Dysbiosis in the periodontal microbiota is associated with the development of periodontal diseases. Little is known about the initiation of dysbiosis.
Bernaerts, Kristel, Boon, Nico, Hernandez Sanabria, Emma, Herrero, Esteban Rodriguez, Quirynen, Marc, Slomka, Vera, Teughels, Wim   +6 more
core   +3 more sources

Evaluating the Patient-Reported Outcomes Measurement Information System scales in acute intermittent porphyria. [PDF]

, 2020
PurposeAcute intermittent porphyria (AIP) is a rare inborn error of heme biosynthesis characterized by life-threatening acute attacks. Few studies have assessed quality of life (QoL) in AIP and those that have had small sample sizes and used tools that ...
Anderson, Karl E, Balwani, Manisha, Bissell, D Montgomery, Bonkovsky, Herbert L, Desnick, Robert J, Erwin, Angelika, Keel, Siobán, Levy, Cynthia, McGuire, Brendan, Montgomery, Guy H, Naik, Hetanshi, Overbey, Jessica R, Phillips, John D, Wang, Bruce, Winkel, Gary   +14 more
core   +1 more source

Polyp Detection and Segmentation using Mask R-CNN: Does a Deeper Feature Extractor CNN Always Perform Better? [PDF]

2019 13th International Symposium on Medical Information and Communication Technology (ISMICT), 2019
Automatic polyp detection and segmentation are highly desirable for colon screening due to polyp miss rate by physicians during colonoscopy, which is about 25%. However, this computerization is still an unsolved problem due to various polyp-like structures in the colon and high interclass polyp variations in terms of size, color, shape, and texture. In
arxiv   +1 more source

Effects of heme oxygenase isozymes on Leydig cells steroidogenesis [PDF]

, 2009
In the present study, we demonstrate the expression of heme oxygenase (HO) isozymes, HO-1 and HO-2 (listed as HMOX1 and HMOX2 in the MGI Database), in MA-10 Leydig tumor cells and its effect on steroidogenesis. The well-known HO inducer, hemin, increased
Besio Moreno, Marcos Alberto, Cymeryng, Cora Betriz, Monzón, Casandra Margarita, Pagotto, Romina María del Luján, Pignataro, Omar Pedro, Piotrkowski, Barbara, Reche, Cecilia   +6 more
core   +1 more source

Structure and function of the bacterial heterodimeric ABC transporter CydDC: stimulation of ATPase activity by thiol and heme compounds. [PDF]

, 2014
In Escherichia coli, the biogenesis of both cytochrome bd-type quinol oxidases and periplasmic cytochromes requires the ATP-binding cassette-type cysteine/GSH transporter, CydDC.
Baldwin, SA, Booth, WI, Bullough, PA, Nyathi, Y, Poole, RK, Postis, V, Shepherd, M, Tzokov, SB, Xie, H, Yamashita, M   +9 more
core   +3 more sources

Import of cytochrome c into mitochondria [PDF]

, 1987
The import of cytochrome c into mitochondria can be resolved into a number of discrete steps. Here we report on the covalent attachment of heme to apocytochrome c by the enzyme cytochrome c heme lyase in mitochondria from Neurospora crassa. A new method
Basile G., Burnette W. N., Chance B., Dumont M. E., Ernst V., Estabrook R. W., Freitag H., Gasser S. M., Hackenbrock C. R., Hay R., Heller J., Hennig B., Hennig B., Hennig B., Kanarek L., Korb H., Laemmli U. K., Lederer F., Matner R. R., Matsuura S., Means G. E., Mihara K., Nicholson D. W., Nozaki M., Pelham H. R. B., Rietveld A., Rietveld A., Rietveld A., Rietveld A., Scarpulla R. C., Schmidt B., Sherman F., Stewart J. W., Taniuchi H., Taniuchi H., Towbin H., Veloso D., Visco C., Yuan P.-M., Zimmermann R., Zimmermann R., Zimmermann R., Zitomer R. S.   +42 more
core   +1 more source

Hepcidin Protects Neuron from Hemin-Mediated Injury by Reducing Iron

Frontiers in Physiology, 2017
Hemin plays a key role in mediating secondary neuronal injury after intracerebral hemorrhage (ICH) and the cell toxicity of hemin is thought to be due to iron that is liberated when hemin is degraded.
Yu-Fu Zhou, Chao Zhang, Chao Zhang, Guang Yang, Zhong-Ming Qian, Meng-Wan Zhang, Meng-Wan Zhang, Juan Ma, Juan Ma, Fa-Li Zhang, Fa-Li Zhang, Ya Ke   +11 more
doaj   +1 more source

General Magnetic Transition Dipole Moments for Electron Paramagnetic Resonance [PDF]

Phys. Rev. Lett. 114, 010801 (2015), 2014
We present general expressions for the magnetic transition rates in beam Electron Paramagnetic Resonance (EPR) experiments of anisotropic spin systems in the solid state. The expressions apply to general spin centers and arbitrary excitation geometry (Voigt, Faraday, and intermediate).
arxiv   +1 more source