Results 71 to 80 of about 43,983 (296)

Metal–Organic Frameworks: Unlocking New Frontiers in Cardiovascular Diagnosis and Therapy

Advanced Science, EarlyView.
Metal–organic frameworks (MOFs), are composed of metal ions and bridging organic ligands, are recognized as an excellent platform for host‐gust chemistry. Its rich structural composition, modifiable sites, and multilevel pore distribution can provide delivery and release of signaling molecules, probes, and therapeutic drugs, which exhibit great medical
Qilu Wu, Yuxiao Feng, Mathilde Lepoitevin, Meng Yu, Christian Serre, Jun Ge, Yuan Huang   +6 more
wiley   +1 more source

A Multi-channel EEG Data Analysis for Poor Neuro-prognostication in Comatose Patients with Self and Cross-channel Attention Mechanism [PDF]

arXiv, 2023
This work investigates the predictive potential of bipolar electroencephalogram (EEG) recordings towards efficient prediction of poor neurological outcomes. A retrospective design using a hybrid deep learning approach is utilized to optimize an objective function aiming for high specificity, i.e., true positive rate (TPR) with reduced false positives (<
arxiv  

In Situ Proliferating Peptide Nanoparticle Augments Multi‐Target Intervention of Secondary Brain Damage Following Subarachnoid Hemorrhage

Advanced Science, EarlyView.
This work designs an in situ proliferating peptide nanoparticle as a flexible resolution that modulates the neuro‐glia unit to enable enhanced multi‐target combinational therapy for secondary brain damage following subarachnoid hemorrhage. Abstract Subarachnoid hemorrhage (SAH), a lethal stroke subtype, involves complex pathological cascades triggered ...
Yibin Zhang, Peisen Yao, Fuxiang Chen, Shufa Zheng, Xuegang Niu, Haojie Wang, Yuanxiang Lin, Bin Gao, Dezhi Kang   +8 more
wiley   +1 more source

Engineered Tissue Models to Decode Host–Microbiota Interactions

Advanced Science, EarlyView.
Host–Microbiota interactions in the human body. Created in BioRender. Ghezzi, C. (2025) https://BioRender.com/ihivskg. Abstract A mutualistic co‐evolution exists between the host and its associated microbiota in the human body. Bacteria establish ecological niches in various tissues of the body, locally influencing their physiology and functions, but ...
Miryam Adelfio, Grace E. Callen, Xuesong He, Bruce J. Paster, Hatice Hasturk, Chiara E. Ghezzi   +5 more
wiley   +1 more source

Rapid and Precise Determination of Zero-Field Splittings by Terahertz Time-Domain Electron Paramagnetic Resonance Spectroscopy

, 2017
Zero-field splitting (ZFS) parameters are fundamentally tied to the geometries of metal ion complexes. Despite their critical importance for understanding the magnetism and spectroscopy of metal complexes, they are not routinely available through general
Belvin, Carina, Dincă, Mircea, Gedik, Nuh, Li, Xian, Lu, Jian, Nelson, Keith A., Ofori-Okai, Benjamin K., Ozel, I. Ozge, Skorupskii, Grigorii, Sun, Lei   +9 more
core   +1 more source

Interaction of hemin with quadruplex DNA [PDF]

Journal of Biological Physics, 2016
A DNA enzyme with peroxidase activity is a G-quadruplex-based DNAzyme formed by hemin and G-quadruplex DNA. Activity of peroxide DNAzymes can be influenced by the structure of quadruplex DNA. In this investigation, the interaction of hemin with T30695 G-quadruplex DNA is evaluated.
Sara Mohammadi Nejad, Leila Hassani, Maryam Ghahremani Nasab, Davood Norouzi   +3 more
openaire   +3 more sources

Cytotoxic effect of hemin in colonic epithelial cell line: Involvement of 18kDa translocator protein (TSPO). [PDF]

, 2014
Aims The aim of this study is to investigate the effect of hemin in colonic epithelial cells (Caco-2) cell proliferation and if this effect was due to a direct modulation of 18-kDa translocator protein (TSPO) and/or heme oxygenase type 1 (HO-1).
Corsi, Lorenzo, Dongmo, Bm, Ferrarini, F, Gemelli, Claudia, Grande, Alexis   +4 more
core   +1 more source

The Porphyromonas gingivalis ferric uptake regulator orthologue binds hemin and regulates hemin-responsive biofilm development.

PLoS ONE, 2014
Porphyromonas gingivalis is a Gram-negative pathogen associated with the biofilm-mediated disease chronic periodontitis. P. gingivalis biofilm formation is dependent on environmental heme for which P.
Catherine A Butler, Stuart G Dashper, Lianyi Zhang, Christine A Seers, Helen L Mitchell, Deanne V Catmull, Michelle D Glew, Jacqueline E Heath, Yan Tan, Hasnah S G Khan, Eric C Reynolds   +10 more
doaj   +1 more source

Human Listening and Live Captioning: Multi-Task Training for Speech Enhancement [PDF]

arXiv, 2021
With the surge of online meetings, it has become more critical than ever to provide high-quality speech audio and live captioning under various noise conditions. However, most monaural speech enhancement (SE) models introduce processing artifacts and thus degrade the performance of downstream tasks, including automatic speech recognition (ASR).
arxiv  

Genome-wide saturation mutagenesis of Burkholderia pseudomallei K96243 predicts essential genes and novel targets for antimicrobial development. [PDF]

, 2014
UNLABELLED: Burkholderia pseudomallei is the causative agent of melioidosis, an often fatal infectious disease for which there is no vaccine. B. pseudomallei is listed as a tier 1 select agent, and as current therapeutic options are limited due to its ...
Atkins, Bakshi, Baugh, Chong, Cuccui, Dance, Davidson, Dong, Doublet, Eckert, Figurski, Freiberg, Gallagher, Haque, Holden, Hu, Kang, Karlyshev, Langmead, Langridge, Lewenza, Lynch, Nandi, Ortega, Sadosky, Sarkar-Tyson, Shalom, Sim, Thibault, Tumapa, van Opijnen, van Opijnen, Wiersinga, Yu, Zhang   +34 more
core   +2 more sources