Results 21 to 30 of about 54,391 (157)

P/Q-type calcium-channel blockade in the periaqueductal gray facilitates trigeminal nociception: a functional genetic link for migraine? [PDF]

, 2002
The discovery of mis-sense mutations in the alpha1A subunit of the P/Q-type calcium channel in patients with familial hemiplegic migraine indicates the potential involvement of dysfunctional ion channels in migraine.
Goadsby, PJ, Yolande E. Knight, Knight, Yolande E., Knight, YE, Goadsby, Peter J., Bartsch, Thorsten, Peter J. Goadsby, Kaube, Holger, Holger Kaube, Kaube, H, Thorsten Bartsch, Bartsch, T   +11 more
core   +1 more source

CACNA1A-p.Thr501Met mutation associated with familial hemiplegic migraine: a family report

The Journal of Headache and Pain, 2021
Background and aims Hemiplegic migraine (HM) is a rare form of migraine characterized by the presence of a motor and other types of aura. HM can be sporadic or familial.
Marina Romozzi, Guido Primiano, Eleonora Rollo, Lorena Travaglini, Paolo Calabresi, Serenella Servidei, Catello Vollono   +6 more
doaj   +1 more source

Diagnostic challenges in sporadic hemiplegic migraine: a case report [PDF]

, 2022
Case Presentation Female, 62 years old, history previous of hypertension and multiple cavernomatosis, admitted to our service emergency room with hypothesis of stroke. The patient presented headache associated with nausea and phosphenes in the right eye,
Pozzobon, Pedro Machry, Sousa-Santos, Patrick Emanuell, Baston , Ana Beatriz, Teixeira, Igor de Lima e, Alvarenga, Tarcísio Nunes, Santos, Itamar Meireles   +5 more
core   +1 more source

Serial magnetic resonance imaging findings during severe attacks of familial hemiplegic migraine type 2: a case report

BMC Neurology, 2021
Background Hemiplegic migraines represent a heterogeneous disorder with various presentations. Hemiplegic migraines are classified as sporadic or familial based on the presence of family history, but both subtypes have an underlying genetic etiology ...
David Fear, Misha Patel, Ramin Zand
doaj   +1 more source

Changes in Plasma Lipid Levels Following Cortical Spreading Depolarization in a Transgenic Mouse Model of Familial Hemiplegic Migraine

Metabolites, 2022
Metabolite levels in peripheral body fluids can correlate with attack features in migraine patients, which underscores the potential of plasma metabolites as possible disease biomarkers.
Inge C. M. Loonen, Isabelle Kohler, Mohan Ghorasaini, Martin Giera, Arn M. J. M. van den Maagdenberg, Oleg A. Mayboroda, Else A. Tolner   +6 more
doaj   +1 more source

Hemiplegic Migraine

Current Neurology and Neuroscience Reports, 2023
Arathi Nandyala, Jessica Ailani
exaly   +1 more source

Imaging the inflammatory phenotype in migraine

The Journal of Headache and Pain, 2022
Several preclinical and clinical lines of evidence suggest a role of neuroinflammation in migraine. Neuroimaging offers the possibility to investigate and localize neuroinflammation in vivo in patients with migraine, and to characterize specific ...
Rune Häckert Christensen, Cédric Gollion, Faisal Mohammad Amin, Michael A. Moskowitz, Nouchine Hadjikhani, Messoud Ashina   +5 more
doaj   +1 more source

Familial Hemiplegic Migraine Type 3 (FHM3) With an SCN1A Mutation in a Chinese Family: A Case Report

Frontiers in Neurology, 2018
Familial hemiplegic migraine (FHM) is a rare, monogenic, autosomal dominant subtype of migraine, in which three genes, CACNA1A, ATP1A2, and SCN1A, are currently known to be involved.
Na Shao, Haining Zhang, Xue Wang, Wuqiong Zhang, Miaomiao Yu, Hongmei Meng   +5 more
doaj   +1 more source

New CACNA1A deletions are associated to migraine phenotypes

The Journal of Headache and Pain, 2018
Background Familial hemiplegic migraine type 1 (FHM1) is a form of migraine with aura caused by heterozygous mutations in 4 genes: CACNA1A, ATP1A2, SNC1A and PRRT2, but further heterogeneity is expected.
G. S. Grieco, S. Gagliardi, I. Ricca, O. Pansarasa, M. Neri, F. Gualandi, G. Nappi, A. Ferlini, C. Cereda   +8 more
doaj   +1 more source

Neurovascular changes in magnetic resonance imagining and single-photon emission computed tomography during migraine attack in patients with FHM2 mutations

Cephalalgia Reports, 2020
The aim of this article is to provide neuroimaging data on cases with familial hemiplegic migraine (FHM). A 14-year-old male presented normal diffusion-weighted magnetic resonance imaging (DWI) and fluid-attenuated inversion recovery (FLAIR) findings ...
Azusa Nagai, Daiki Tanaka, Kiyomi Kuroshima, Shigehisa Ura, Kazuto Yoshida, Yuji Takahashi, Ichiro Yabe   +6 more
doaj   +1 more source